Synthetic Chemistry

🎄 𝙈𝙚𝙧𝙧𝙮 𝘾𝙝𝙧𝙞𝙨𝙩𝙢𝙖𝙨 𝙩𝙤 𝙚𝙫𝙚𝙧𝙮𝙤𝙣𝙚!🎄 We wish you a very special Christmas and relaxing holidays!  Enjoy quality time with your loved ones and stay healthy! 🍀🎅 We will take some time off ourselves and are excited to dive back into the world of Microwave Synthesis next year.  Stay tuned until January 7th, 2025 ! #microwavedigestion #microwavesynthesis #happyholidays #Christmas #AntonPaar

𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁: 𝗖𝗼𝗯𝗮𝗹𝘁 𝗧𝗲𝗹𝗹𝘂𝗿𝗶𝗱𝗲 𝗡𝗮𝗻𝗼𝗳𝗶𝗯𝗲𝗿𝘀 Last we heard about the properties of tellurium and its meaning in chemistry. In synthesis, the metalloid was not very common until it gained attraction in nanomaterial synthesis. Nowadays, tellurium is often used as a dopant  for electrocatalysts or nanophosphors to modify the properties of these nanoparticles.  In a recent study, a Czech group presented the synthesis of tunable cobalt telluride nanofibers in aqueous media. By varying the shape directing agent, different morphologies of the nanoparticles can be obtained. Highly effective fibrous particles were obtained with simple HCl in catalytic amounts. The obtained nanofibers are excellent photoelectrocatalysts and were used for the generation of 3D-printed electrodes for oxygen evolution reactions Reference:  S. Subhadarshini et al., Mater. Today 2024, 74, 34 Sounds interesting? Find various protocols for microwave-assisted synthesis of tunable nanoparticles in our free application database:  https://bit.ly/3PlMuHt #microwavesynthesis #nanomaterials #chemistrythatmatters #Monowave #AntonPaar

𝗪𝗵𝗮𝘁'𝘀 𝘀𝗼 𝘀𝗽𝗲𝗰𝗶𝗮𝗹 𝗮𝗯𝗼𝘂𝘁 𝗧𝗲𝗹𝗹𝘂𝗿𝗶𝘂𝗺? Tellurium is a rare, brittle, greyish metalloid of the chalcogen group, which forms several telluride and oxide ores. Sometimes it occurs even in native form, typically accompanying gold and silver. The element was discovered in 1782, when Austrian mineralogist Müller von Reichenstein, evaluated gold ores for unexpected low gold levels. Pure tellurium is obtained as a byproduct in copper refining, where it can be recovered from the anode sludge. Its industrial relevance  is rather minor, due to the toilsome and expensive isolation. In recent years, the synthesis of CdTe and similar nanoparticles has attracted interest for applications in photovoltaic and thermoelectric devices. Microwave irradiation facilitates the development and synthesis of these compounds to enhance the performance of solar panels. Our microwave reactors from the Monowave series are the best tools to serve the research for novel nanomaterials: https://loom.ly/Xi2NEI4  #microwavesynthesis #nanomaterials #chemistrythatmatters #Monowave #AntonPaar

𝗜𝘁'𝘀 𝗡𝗼𝗯𝗲𝗹 𝗗𝗮𝘆! On December 10th, the world celebrates scientific excellence with the Nobel Prize ceremony, and this year, chemistry is once again in the spotlight. The famous award acknowledges not only individual achievements but the power of chemistry to address global challenges and advance human knowledge. From pioneering new materials to breakthroughs in molecular biology and sustainable synthesis, Nobel-winning research in chemistry shapes the future of technology, healthcare, and the environment. Each laureate reminds us of the creative potential within molecules and reaction - providing solutions that are vital for a sustainable and healthy world. After several awards for synthesis techniques in recent years, the 2024 Nobel Prize in chemistry was awarded for computational design and protein structure prediction by the aid of AI. Let's honor all the groundbreaking scientists contributing to innovative research  🍾 Fun fact: so far, only 5 persons have been awarded the Nobel Prize twice - four of them received at least one Nobel Prize in Chemistry! Picture credit: This image was originally posted to Flickr by AlphaTangoBravo / Adam Baker at https://loom.ly/4UN0aog #chemistrythatmatters #NobelPrize #proteindesign  #AntonPaar

𝗔 𝘀𝗽𝗲𝗰𝗶𝗮𝗹 𝗱𝗮𝘆 𝗰𝗼𝗺𝗶𝗻𝗴 𝘂𝗽! Do you know Percy L. Spencer?  The American physicist is credited for  the invention of microwave oven in the 1940s His initial patent application was filed in1945 and a decade later the first microwave kitchen oven appeared on the scene. But not before the late 1960s these devices became reasonably sized and affordable. In the 1970s microwave irradiation was used the first time for chemical laboratory purpose. After experiences in sample preparation, syntheses were condcuted not before 1986. The initial steps in microwave synthesis happened in domestic ovens, but the breakthrough required dedicated instruments. These specific synthesis instruments appeared on the scene 25 years ago, establishing the new class of monomode reactors. Nowadays, microwave synthesiis is a well-acknowledged add-on to the chemist's tool box, speeding up R&D and opening new pathways in material science In appreciation of the 60th anniversary of Percy Spencers's patent filing, National Microwave Day was established on December 6th, 2005. Join us in celebrating this day for the 20th time tomorrow! 🎇🎆🍾 #chemistrythatmatters #microwavesynthesis #monowave #microwaveovenday #AntonPaar

𝗧𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗯𝗲𝗵𝗶𝗻𝗱 𝘀𝗽𝗮𝗿𝗸𝗹𝗲𝗿𝘀: 𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆 𝗹𝗶𝗴𝗵𝘁𝗶𝗻𝗴 𝘂𝗽 𝘄𝗶𝗻𝘁𝗲𝗿𝘁𝗶𝗺𝗲! It's this special time of the year, when it get's darker outside and people create cozy atmospheres with illuminations, candles and sparklers. Have you ever wondered how sparklers create those mesmerizing sparks? Here’s a quick breakdown of the chemistry behind them. Sparklers use powdered metals - often aluminum or magnesium - to create bright, white sparks. The sparkler stick is coated with a pyrotechnic mix of an oxidizer (like barium nitrate), sulfur, charcoal, and metal powder, with a combustible binder to hold it all together. For golden sparks, iron or titanium is added, and if you’ve seen colored sparks, that’s caused by different metal salts. All it takes is a lighter to set off the reaction, and there you go - your personal handheld light show! 🌟 Remember, though, sparks can also occur in your microwave reactor! But this is certainly where you don't want them! Thus, when using metal catalysts make sure to use fine powders and carefully calculate the required amount to prevent this effect.🎇 #chemistryinreallife #chemistrythatmatters #Christmas #Monowave #AntonPaar

𝗔𝗻𝘁𝗼𝗻 𝗣𝗮𝗮𝗿 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗗𝗮𝘁𝗮𝗯𝗮𝘀𝗲 - 𝗿𝗲𝗮𝗰𝗵𝗶𝗻𝗴 𝗻𝗲𝘄 𝗵𝗲𝗶𝗴𝗵𝘁𝘀! We are excited to share that we’ve hit a major benchmark in our microwave synthesis application database! 🍾 With a fascinating publication from a Serbian research team on synthesizing tunable doped strontium fluoride nanoparticles, which can be used in detection probes for heavy metal contaminations in water, our collection now includes 𝟯.𝟬𝟬𝟬 different synthesis examples! The data is extracted from 𝗼𝘃𝗲𝗿 𝟰.𝟬𝟬𝟬 Peer-reviewed publications featuring microwave synthesis protocols using Anton Paar reactors. Our database continues to grow day by day, thanks to the groundbreaking work of our diligent clients. It covers a diverse range of applications - from classic organic synthesis transformations in pharmaceutical research to nanomaterials for batteries and solar cells, metal-organic frameworks, polymers, and much more. Stay current with the latest research trends and explore our ever-growing, free application database here: https://bit.ly/3PlMuHt Follow us for regular updates and highlights from our database! #microwavesynthesis #applicationdatabase #worldofsynthesis #chemistrythatmatters #Monowave #AntonPaar

𝗪𝗵𝘆 𝗺𝗼𝗻𝗼𝗺𝗼𝗱𝗲 𝗿𝗲𝗮𝗰𝘁𝗼𝗿𝘀 𝗹𝗲𝗮𝗱 𝘁𝗵𝗲 𝘄𝗮𝘆 𝗶𝗻 𝗺𝗶𝗰𝗿𝗼𝘄𝗮𝘃𝗲 𝘀𝘆𝗻𝘁𝗵𝗲𝘀𝗶𝘀! In literature, the vast majority of microwave synthesis examples are conducted in monomode reactors. Have you ever wondered, why these instruments are THE choice for microwave synthesis? The answer lies in their efficiency and simplicity. After initial steps with domestic ovens and cumbersome multimode instruments during the 1980s, the real interest in microwave synthesis  emerged in the late 1990s. This happened, when monomode reactors were specifically designed for the task. Their single-vessel, small-scale setup makes them perfect for R&D, allowing for quick cycle times and high precision - key factors in research labs. Unlike larger, multi-vessel rotors in multimode instruments, monomode reactors offer ease and flexibility without the hassle of complex, parallel setups. Compact and efficient, they save valuable lab space and can be customized with specialized accessories to meet diverse synthesis needs. Anton Paar’s Monowave series takes these advantages to the next level, offering an ideal solution for fast, efficient research in synthesis. Find out how on our website: https://loom.ly/Xi2NEI4 #microwavesynthesis #chemistrythatmatters #Monowave #AntonPaar

𝗠𝗶𝗰𝗿𝗼𝘄𝗮𝘃𝗲𝘀 𝗮𝗻𝗱 𝗰𝗼𝗺𝗯𝗶𝗻𝗮𝘁𝗼𝗿𝗶𝗮𝗹 𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆 - 𝗮𝗰𝗰𝗲𝗹𝗲𝗿𝗮𝘁𝗶𝗻𝗴 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵! Combinatorial chemistry is a collective term for synthesis techniques increasing chemical diversity. By utilizing parallel setups or automated synthesis it allows to accelerate discovery and find more needles in the haystack by creating promising product libraries in short time. Especially in pharmaceutical industry the concept is widely used. As microwave synthesis also contributes to the acceleration of R&D, even with enhanced yields and purity, it is a perfect add-on to combinatorial approaches. Our Monowave 450 provides unattended automated sequential processing of 24 individual reactions, whereas Multiwave 5000 offers Rotor 4x24 for conducting 96 reactions in parallel under identical reaction conditions. This represents the most efficient way for library generation in microwave synthesis. However, the origins of combinatorial chemistry date back to the 1960s, when Bruce Merrifield developed the solid-phase peptide synthesis with amino acids bound to polymer resins. 40 years ago, the initiator and pioneer of combinatorial chemistry was awarded the Nobel Prize in Chemistry. #microwavesynthesis #chemistrythatmatters  #combinatorialchemistry  #Monowave #Multiwave #AntonPaar

𝗗𝗼 𝘆𝗼𝘂 𝗸𝗻𝗼𝘄 𝘁𝗵𝗲 𝘀𝗽𝗲𝗰𝗶𝗮𝗹𝘁𝗶𝗲𝘀 𝗼𝗳 𝘁𝗵𝗲 𝗞𝗻𝗼𝗲𝘃𝗲𝗻𝗮𝗴𝗲𝗹 𝗰𝗼𝗻𝗱𝗲𝗻𝘀𝗮𝘁𝗶𝗼𝗻? The Knoevenagel condensation is one of the most powerful and widespread used bond forming reaction in organic synthesis. Typically, as developed in the 1890s by German chemist Emil Knoevenagel, an aldehyde undergoes  nucleophilic addition with a hydrogen active compound, followed by subsequent  elimination of water to form the enone.  Hence, it can be considered a special variation of an Aldol condensation. The Doebner modification uses malonic acid, leading to a decarboxylation to form the final product. Microwave irradiation is significantly enhancing reaction rates for Knoevenagel reactions, but decarboxylation is somewhat challenging for sealed-vessel microwave reactions as the formed carbon dioxide can lead to a significant pressure increase, reaching the operation limits of the reaction vessels. Hence, thorough calculation of amounts and molar ratios is required to keep the resultng pressure with the instrument specs. Nevertheless, numerous examples of Knoevenagel condensation resulting in various aliphatic, aromatic or (hetero)cyclic compounds can be found in our free application database: https://bit.ly/3PlMuHt #microwavesynthesis #chemistrythatmatters  #applicationdatabase  #Monowave #AntonPaar