organoid@KUL

What better way to start the New Year than by diving into the fascinating world of CRISPR and organoids? Join the organoid@KUL community for an insightful session with two leading experts who will demonstrate how to leverage CRISPR technology to address critical research questions in human diseases modeled using organoids. Maarten Geurts employs CRISPR technology to explore - amongst others - the role of specific gut epithelial cells in detecting intestinal contents, shedding light on physiological processes such as appetite regulation, bowel movements, and insulin sensitivity. Read more here (https://lnkd.in/esDG3-Qe). Julian Grünewald has made significant contributions to the CRISPR field, including the development of prime editors with compact, untethered reverse transcriptases (https://lnkd.in/e9pT8gaW) and base editors with reduced RNA off-target effects (https://lnkd.in/eQvunVsG). His recent work focuses on modeling and treating cardiac diseases using CRISPR. Don't miss this opportunity to learn from these experts on 7 January 2025, at 1 PM, KU Leuven, campus Gasthuisberg. All welcome!

Organoid@KUL will be participating in the Word Organoid & Organ-on-Chip conference held on February 11-13th 2025 in Cambridge, UK. Check out Session five: KU Leuven initiative. Academic Research Showcase. Chair Hugo Vankelecom with speakers: Adrian Ranga Marianne Carlon Emma Laporte. Full program below. Welcome!

Please join us next week Monday for the organoid@KUL seminar series. This time Mostafa Kiamehr will present his beyond-state-of-the-art liver models and their applications for drug discovery. Roel Quintens will join us from SEK CEN providing insights on brain organoids in the field of radiation and space applications.

Please join us next week Monday for the organoid@KUL seminar series. This time Mostafa Kiamehr will present his beyond-state-of-the-art liver models and their applications for drug discovery. Roel Quintens will join us from SEK CEN providing insights on brain organoids in the field of radiation and space applications.

Check out: GET-IN partner Marianne Carlon and her team went to primary school to teach the youngest generation of scientists.

During our sunny EU H2020 JOINTPROMISE Project consortium meeting at Patras, Greece we discussed the integration of our automated organoid manufacture platform and it’s validation at the preclinical stage for deep osteochondral defects of the joint, during the final year of the project. A big thanks to the colleagues at Foundation for Research and Technology - Hellas (FORTH) ICEHT, Maria Klapa, Alexandra Paxinou and Paraskevi Zagana, Dr for the excellent hospitality ! KU Leuven , Fraunhofer Institute for Production Technology IPT , STEMCELL Technologies , MERLN Institute for Technology-Inspired Regenerative Medicine @

organoid@KUL had a very interesting network meeting with UGhent on connecting expertise on #organoids and #organ-on-a-chip. This research exchange meeting was very fruitful, and new alliances for collaboration were born. An event and exercise that certainly warrants to be repeated regularly 👏 😀 Frauke Christ Marianne Carlon Adrian Ranga Ioannis Papantoniou Joana Rocha-Pereira Hugo Vankelecom Gudrun Antoons Laetitia Cicchelero

Congratulations to our organoid@KUL colleague Colinda Scheele, who has been awarded one of the prestigious and highly competitive 2024 ERC Starting Grants from the European Research Council (ERC). Colinda’s research will focus on how mutant cells in normal tissues can transform into cancer.  Her research builds on findings that the sequence in which mutations are acquired affects a cell's cancerous potential. She will develop a novel sequential somatic gene editing technology to study how different mutation sequences influence cell behavior and their environment in the mammary gland. "This innovative approach could lead to a better understanding of tumor initiation and improve early cancer intervention strategies for breast cancer and beyond." Check out her remarkable research on mammary organoids models: https://lnkd.in/etgb9PSE https://lnkd.in/egv-nSVv

The Hugo Vankelecom lab will showcase its 3D tissue modelling work at the GIGA day in Liege September 24. Everybody welcome - free registration! Sartorius Corning LifeScience LiveDrop Dulis Belgium - Labware For You

📰 🆕 #HYPIEND partner Hugo Vankelecom from KU Leuven showcased pituitary stem cells and organoid technology at International Society for Stem Cell Research 2024 Annual Meeting HYPIEND was mentioned as one of the projects in which this technology is used to study the impact of endocrine disrupting chemicals #EDCs ⚗ 👉 https://lnkd.in/djqTnmat