Mightex

Happy Thanksgiving from the Mightex team! We loved coming together and sharing great moments. 🦃🍂

🔔 Don’t miss your chance to be awarded up to $3000 USD! 🔔 Are you a research student or postdoc using Mightex equipment in your research? Submit your application for the Mightex Research Excellence Prizes today ➡ https://lnkd.in/g7FHmEQh

Haleigh N. Mulholland and colleagues at the University of Minnesota shed light on how modular activity self-organizes in the immature cortex. Despite the brain's immaturity at birth, neural activity forms into predictable, columnar patterns, hinting at fascinating underlying mechanisms. Using calcium imaging and optogenetics, the team demonstrated how lateral inhibition and local excitation drive these patterns. Leveraging the Mightex #Polygon1000, they revealed: 1️⃣ Cortex activity naturally organizes into periodic patterns. 2️⃣ Characteristic frequencies of activity remain stable across trials. 3️⃣ Stimulating at these frequencies synchronizes neural responses. 4️⃣ Stimuli at non-characteristic frequencies produce intermediate activity patterns. These findings clarify the physiological underpinning of columnar cortical activity in immature animals. 👉 Read the full paper here:https://lnkd.in/gwa-Bt_m

Just visited Dr.Geoff Lau’s lab at the City University of Hong Kong to see our #Polygon and #OASIS systems in action, supporting their research.

📢 Are you a student or postdoc using Mightex equipment in your research? Don’t miss the chance to apply for the Mightex Research Excellence Prizes! 🏆 Prizes:  🥇 1st Place: $3,000 🥈 2nd Place: $2,000 🥉 3rd Place: $1,000 🎖️ Honorable Mentions: $500 🗓 Deadline: December, 31 2024 This is a great opportunity to gain recognition for your research efforts. Apply today! 👉 https://lnkd.in/g7FHmEQh 

We're proud to support researchers who recently presented their work using Mightex tools at the Society for Neuroscience (#SfN2024) in Chicago and the Lake Conference in Seattle.These projects showcase important advancements in neuroscience with the help of Mightex #Polygon and #OASIS Implant. SFN 2024 🎓 Hassan Hosseini Topic: Noradrenergic Modulation in Grin2a Mutant Mice 🎓 Saeed Omidi Topic: 2D Optical Interface to 3D Engineered Neural Cultures 🎓 Jayant Rai Topic: cAMP Signaling in Learning and Memory Lake Conference 🎓 Hassan Hosseini Topic: Dysfunctional mPFC Inhibitory Tone in GluN2A NMDA Receptor-deficient mice If you’re attending #ASCB2024 or other upcoming conferences, consider applying for a Mightex Travel Award to help with travel expenses. Learn more here: https://lnkd.in/gsRugdVp

Week 10 Highlight: Created a Focus Assist Device for Creative Electron, Inc., where my design was recognized as one of the Top 4 along with Marissa Renteria, Jonathon Gracia, and Stacy Pena. Thanks again to Kate MacArevey-Colello, KC Cadacio, and Devan M. for setting up this opportunity. Here’s what we were given: • Devise and prototype a mechanism enabling the mounting and focusing of a Mightex camera fitted with a Arducam lens. The camera will be focused while mounted to a Toshiba x-ray image intensifier. Here’s what the problem was: • It’s not currently possible to focus the lens on the camera while it is installed in the camera mount and image intensifier. Technicians must mount the camera, check the focus, then remove the camera, adjust the focus, then reinstall to check. This can require multiple iterations and several phases of attachment/detachment of the camera. Here’s what I did: • Created a 3D printed prototype using Autodesk Fusion 360, where a rotary dial would adjust the focus ring of the camera • Created a Bill of Materials listing all individual parts used • Prepared a presentation for Creative Electron staff where I covered the overview of my design, the assembly process, and CAD-generated images #RobotsAndLasers #Mightex #Arducam #Toshiba #Autodesk #Fusion360 #3DPrinting #Ultimaker #UltimakerS5 #Creality #Ender #AdditiveManufacturing #EngineeringTechnician #Engineering MiraCosta College Community Education & Workforce Development

#CELLBIO2024 Travel Awards Now Open! 🚨 Heading to #ASCB 2024 and using Mightex products? You could win $500 to help cover your travel expenses! Don’t wait—apply now! More details here: https://lnkd.in/gsRugdVp

🔔 Check out our new blog post 🔔 Using the Mightex #Polygon , Severin and colleagues recently revealed unexpected daily oscillations in neuronal membrane capacitance in excitatory neurons of the visual cortex and hippocampal dentate gyrus. This paper combines patch clamp electrophysiology with targeted optogenetics to interrogate integration of dendritic inputs, with implications for neuronal excitability and function throughout the day. 👉 Read more about their work here: https://lnkd.in/gK28-CuJ

We’re glad to introduce one of our #MicroTAS2024 Polygon customers, Alan S.His research, titled “Realizing High-Viability Single Cell Printing in Acrylate Hydrogels by Overcoming Oxygen Toxicity,” utilized the Mightex #Polygon for important advancements. Thank you to all our customers for trusting and using our products in your work. We appreciate being part of this dedicated community and remain committed to supporting continued progress and innovation in the field.