Biosynth

We’re excited to be exhibiting at the 2025 CACLP in Hangzhou, China, from March 22-24 at the Hangzhou Grand Convention & Exhibition Center. At Biosynth, we’re committed to supporting your projects for clinical diagnostics or other applications. Our innovative range of products for IVD includes: -Antigens, antibodies, biospecimens, and controls -Enzymes and enzyme substrates -Complex peptides and proteins Biosynth's IVD raw materials are ideal for developing high-performing immunoassay applications. We have a curated selection of first-to-market proteins and monoclonal antibodies for new emerging viruses. Read more about our Raw Materials for In-vitro Diagnostics: https://lnkd.in/d4f2Zx4P If you’re attending CACLP, visit us at Hall 4, Booth E0305 and meet with our team Philip Noone. CDir, Pragya Maheshwari, and Dongjia(Davy) Lu. We’d love to discuss how we can support your projects. #CACLP #IVD #Diagnostics 

Use the power of bioconjugation to create next-generation therapeutics with enhanced drug delivery, stability and bioavailability. Biosynth offers a full range of bioconjugation services, from concept all the way to GMP production. Our facilities are equipped to produce high-quality bioconjugates at various scales. Our services include: • Bioconjugation Process Development: Optimizing bioconjugation processes for each molecule to ensure high yields.    • Bioconjugate Manufacturing: Manufacturing bioconjugates for preclinical, clinical, and commercial needs, including GMP manufacturing.    • Analytical Services for Bioconjugates: Providing comprehensive analytical services, including characterization, potency testing, and stability testing.  To find out how bioconjugation is a valuable tool for addressing challenges in pharmaceutical drug development read our latest blog. https://lnkd.in/ewKhv7QD Whether you need pharmaceuticals, excipients, or reagents for diagnostics, Biosynth's complete custom bioconjugate services are perfect for you. Visit us today https://lnkd.in/ewhKUJ8H #bioconjugation #custombioconjugates #bioconjugatedrugs #conjugatevaccines #polymers #pharmaceuticals #therapeutics #diagnosticreagents #linkers #PEGs #innovation

In the pharma industry, adherence to quality standards and documentation is vital. With over 60 years in complex chemistry manufacturing and supply, and specialities in innovation chemistry, Biosynth work as a partner for both bulk supply of critical products or in developing and manufacturing our customers' products. Our global quality team manage our internal quality management system and perform regular internal audits to ensure maximum quality. Special attention is given to compliance issues, in particular to API manufacturing, testing and handling, change control requirements, method and process validation, controlled substance handling and proper documentation, including batch records. Read more about our quality and regulatory support services and the role of batch records in delivering quality to our customers. #Chemicalmanufacture #PharmaServices #InnovationChemistry #ComplexChemicalProducts #GMP #firstideatofinishedproduct #qualityassurance #pharma

At Biosynth, we recognize the unique advantages of macrocycles: their ability to engage larger, flatter protein surfaces, their inherent structural similarity to natural degrons, and their demonstrated capacity to stabilize protein-protein interactions.  Researchers are actively seeking ways to target "undruggable" proteins, and macrocyclic peptides offer a promising avenue. By offering a dedicated macrocyclic peptide service, Biosynth can empower researchers to explore this exciting area of drug discovery. Contact us to accelerate your macrocyclic project today https://lnkd.in/eawkrBfq #MacrocyclicPeptides #Macrocycles #PeptideDiscovery #DrugDiscovery #Biosynth 

Biosynth's new on-cell screening platform is a powerful tool for dealing with complex targets like membrane proteins or protein-protein interactions. Our platform maintains the native conformation of your target protein, ensuring accurate screening even for complex membrane proteins. This streamlined process reduces the time and resources required to identify lead candidates, helping you bring your therapeutic to market faster. Watch this short introduction to the platform and how it can benefit your project.  [https://lnkd.in/eiMhjqnr] For more details, visit the website. https://lnkd.in/eeuYKVtG Contact our experts to start your biopanning project. https://lnkd.in/eawkrBfq #drugdiscovery #drugtargets #peptideresearch #leadcandidate

Are you working on the discovery and development of novel peptide therapeutics? Learn how Biosynth's CLIPS™ multicyclic peptide synthesis can revolutionize your drug discovery efforts. Explore the benefits of constrained peptide structures for enhanced bioactivity in our blog https://lnkd.in/eydJP-mT With improved properties, including enhanced target specificity and improved pharmacokinetics, the technology's efficiency and ability to produce isomerically pure products further add to its attractiveness for drug discovery applications. Visit our website to learn more about how Biosynth's CLIPS™ technology can revolutionize your drug discovery efforts with multicyclic peptides. https://lnkd.in/eY6SjiWT #macrocycles #multicyclic #peptidediscovery #biosynthpeptides

The rapid rise of RNA therapeutics marks one of the most profound shifts in modern medicine, from antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs) to mRNA-based vaccines. This revolution would not be possible without nucleotides. From the first FDA-approved oligonucleotide drug, fomivirsen (in 1998) to today’s mRNA vaccines and siRNA therapies, nucleotide chemistry has been the driving force behind these breakthroughs.   Over the years, there have been many advancements in delivery systems and chemical modifications, especially in the design and synthesis of nucleotides, which ultimately dictate these molecules' stability, efficacy, and specificity. Key modifications such as 2’-fluoro, 2’-O-methyl, and phosphorothioate linkages, and even solid-phase synthesis, have been instrumental in enhancing resistance to nucleases, optimizing binding affinity, and reducing immunogenicity to determining the success of RNA-based drugs.   Explore our latest whitepaper and learn more about nucleotides and how they have transformed the field of therapeutics.   https://lnkd.in/e5AksjrX   At Biosynth, we are at the forefront of nucleotide chemistry, and we specialize in these critical modifications. With decades of expertise in custom synthesis and modification strategies, we can help you overcome the critical challenges of RNA development. Contact us at https://lnkd.in/e-bgvrBC to find out more. #RNATherapeutics #Nucleotides #Oligonucleotides #mRNA #siRNA #ASO #Biosynth #RNAvaccine

𝗦𝘁𝗿𝗲𝗮𝗺𝗹𝗶𝗻𝗲 𝗬𝗼𝘂𝗿 𝗗𝗿𝘂𝗴 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 & 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝗝𝗼𝘂𝗿𝗻𝗲𝘆 𝘄𝗶𝘁𝗵 𝗕𝗶𝗼𝘀𝘆𝗻𝘁𝗵 Scientists in the pharmaceutical industry face numerous challenges navigating the complexities of drug discovery, development, and manufacturing. A crucial factor for success is partnering with reliable providers offering high-quality products and services. Biosynth offers a comprehensive range of solutions designed to address these challenges. • 𝗖𝘂𝘀𝘁𝗼𝗺 𝗖𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗦𝘆𝗻𝘁𝗵𝗲𝘀𝗶𝘀: With over 55 years of experience, our skilled custom synthesis teams can start from your first ideas, route scouting and develop a synthesis method. We welcome projects involving challenging multi-step synthesis and are committed to innovating our internal processes to enable the synthesis of complex compounds. This capability is especially beneficial in early-stage research and lead optimization. • 𝗣𝗲𝗽𝘁𝗶𝗱𝗲 𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆 𝗘𝘅𝗽𝗲𝗿𝘁𝗶𝘀𝗲: From the simple to the most complex peptide projects, Biosynth provides expert service and quality with a focus on making the most biologically relevant product for your target. Our specialized knowledge in this area can prove invaluable for projects involving peptide therapeutics and peptide antigens. • 𝗔𝗻𝗮𝗹𝘆𝘁𝗶𝗰𝗮𝗹 𝗦𝗲𝗿𝘃𝗶𝗰𝗲𝘀: Reliable analytical services are essential throughout the drug development process. We offer a range of services, including NMR, MS, and chromatography, supporting research from characterization to quality control. • 𝗡𝗖𝗘 𝗮𝗻𝗱 𝗔𝗣𝗜 𝗠𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴: GMP manufacturing for consistent and reliable drug substance supply. • 𝗕𝘂𝗹𝗸 𝗥𝗲𝗮𝗴𝗲𝗻𝘁 𝗦𝘂𝗽𝗽𝗹𝘆: Beyond custom synthesis, Biosynth are leaders in the secure supply of high-quality bulk reagents for pharma and diagnostics with full documentation and change control as needed. From small molecules, peptides, enzymes and other biologicals, including starting materials, intermediates, formulation ingredients and more. • 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗥𝗲𝗮𝗴𝗲𝗻𝘁 𝗦𝘂𝗽𝗽𝗹𝘆: For research, development as well as for long term assay use, Biosynth supplies products including carbohydrates, nucleosides, antigens and plasma, alongside catalog and custom peptides and antibodies. What distinguishes Biosynth is our commitment to quality, reliability, and scientific expertise. Biosynth understands the intricacies of pharmaceutical research and offers tailored solutions to meet specific needs. For scientists seeking a partner to support their drug discovery, development, and manufacturing efforts, explore Biosynth's offering. Our comprehensive suite of services and products can be a valuable asset in accelerating research and ultimately bringing life-changing therapies to patients. www.biosynth.com Speak to an expert today. www.biosynth.com/contact #drugdiscovery #drugdevelopment #pharmaceuticals #chemistry #API #manufacturing #biosynth #partnerships #science #research #innovation

Representing February in our 2025 calendar is Burning, a Chinese Ginger Cat belonging to Pola Li, a People Operations Officer based at our Suzhou site. Fun fact: Ginger cats are almost always male. A ginger coat is due to the O (Orange) gene, which is carried by the X chromosome. Since male cats have only one X chromosome (XY) they only need one copy of the orange gene to be ginger, whereas female cats (XX) need two copies making ginger female cats rarer than the males.

Read the latest editorial by Biosynth's own Peter Timmerman, Head of Peptide Science, published by SENGLOBAL LTD in International Biopharmaceutical Industry: Peptide Therapeutics: Unleashing the Power of Precision Medicine. https://lnkd.in/dEdSW54H In the ever-evolving landscape of drug discovery, peptide therapeutics have emerged as a beacon of hope, offering a unique blend of specificity, synthetic accessibility, and therapeutic efficacy. This article delves into the advancements in peptide therapeutics, highlighting their potential to revolutionize drug development. For a full list of Biosynth's publications, visit our website: https://lnkd.in/eK3imT4j #PeptideTherapeutics #PrecisionMedicine #DrugDiscovery #BiopharmaceuticalIndustry