Biomarker (BMKGENE) Europe

 🎉 BMKGENE sequencing services empower impactful science The article published in Nature Communications, SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia. This study shows decreased RNAi component (Dicer and XPO5) and splicing factor (SRSF3 and hnRNPA3) expression correlate with increased COVID-19 severity. BMKGENE provided small RNA and full-length transcriptome sequencing and bioinformatics analysis services for this study. SARS-CoV-2 N protein induces the autophagic degradation of Dicer, XPO5, SRSF3, and hnRNPA3, inhibiting miRNA biogenesis and RNA splicing and triggering DNA damage, proteotoxic stress, and pneumonia. Dicer, XPO5, SRSF3, and hnRNPA3 knockdown increases, while their overexpression decreases, N protein-induced pneumonia's severity. Older mice show lower expression of Dicer, XPO5, SRSF3, and hnRNPA3 in their lung tissues and exhibit more severe N protein-induced pneumonia than younger mice. PJ34, a poly(ADP-ribose) polymerase inhibitor, or anastrozole, an aromatase inhibitor, ameliorates N protein- or SARS-CoV-2-induced pneumonia by restoring Dicer, XPO5, SRSF3, and hnRNPA3 expression. 💡 These findings will aid in developing improved treatments for SARS-CoV-2-associated pneumonia. Learn more about this paper https://lnkd.in/gFk7cyAu #sRNA #ranscriptome #Nanopore #RNA #NatureCommunications #bioinformatics

🎉 Incredible time at the UK Archaea Conference 2025 this week!  🌟 It was a pleasure connecting with many scientists and showcasing our latest multi-omics services at our booth.  Highlights from the conference: 📖 Sharing the latest findings and engaging in discussions about advancements in the field. Thank you to everyone who stopped by our booth and visited our incredible team, Ziming Z., as we explored the potential of this research field! #microbiology #science #sequencing #archaea #BangorUniversity 

💡 Archaea: A microbiological world yet to be discovered 👏 Join us to uncover the mystery of Archaea at the UK Archaea Conference 2025, Bangor University. ⏰ Data: 9th – 10th January 📍 Location: Neuadd Reichel, Bangor University, Ffriddoedd Road, Bangor This meeting is a fantastic opportunity to connect with leading researchers, and shape the future of this exciting field! Our Field Application Specialist, Ziming Z. will be on-site to showcase our latest microbial services and innovations and demonstrate how we can support your research. #science #Archaea #sequencing #metagenomics #microbiology

🔎 Think you know the answer? Let’s find out! 🧬 Dive into our #BMKGENEQuiz and take on today’s challenge! #metagenomics #sciencechallenge #sequencing #science

💡 Exchange ideas and applications on plant and animal genome research We're excited to announce that BMKGENE will be participating in the Plant and Animal Genome Conference (PAG 2025), which will take place from January 10–15, 2025, in San Diego, CA, USA! 🎉 This premier conference is a gathering of the brightest minds in plant and animal genomics, offering a unique opportunity to showcase the latest innovations in biotechnology and bioinformatics. 🌱🐾 Will you be at PAG 2025? Be sure to stop by our booth, where Kevin Bredemeyer, PhD, and Tina Ding will be happy to discuss how BMKGENE is plant and animal genome projects. 🗣 See you in San Diego! 🌞 #PAG2025 #Genomics #Innovation #Bioinformatics #BMKGENE #PlantGenomics #AnimalGenomics #Research #Science #SanDiego #Conference

Over 2024, #BMKGENE has made remarkable strides in disease, cancer, microbial, animal, and plant research. Our dedicated services have facilitated the publication of multiple high-level papers in academic journals. These success story research papers have been published in prestigious international journals like Nature, Nature Genetics, Nature Methods, Cancer Cell, and Nature Communications, amassing a cumulative impact factor surpassing 6700. BMKGENE has been unswervingly committed to delivering high-quality scientific research services, including high-throughput sequencing and bioinformatics analysis, spanning a diverse range of omics studies. The prolific output in 2024 is a resounding testament to our capabilities and efforts. It is a powerful affirmation that propels us forward. BMKGENE will persevere in our pursuit of excellence and continue to provide professional services. #bmkgene #publications #Sequencing #omicsstudy #science

🎆 Happy New Year from all of us at Biomarker Technologies (BMKGENE) Europe! 🎆 As we welcome a brand new year, we reflect on the incredible milestones we’ve achieved together in the past year. Your support has been instrumental in making our journey so special. May this New Year bring fresh opportunities, endless possibilities, and moments of happiness for you and your loved ones. Let’s make 2024 a year of growth, collaboration, and success. Cheers to a wonderful year ahead! 🥂🎉 #BMKGENE #HappyNewYear #2024Beginnings #NewYearJoy #SeasonOfPossibilities

🎥 Relive 2024: The Year That Was! 🌟 From achievements to unforgettable moments, "The Story of BMKGENE 2024" takes you on a journey through an incredible year. Whether you were part of the action or following along, this recap video captures the essence of everything that made 2024 remarkable. 📺 Watch now and reminisce on the highlights that defined a year of innovation, resilience, and inspiration! #BMKGENE2024 #YearInReview #Highlights #2024Recap

This year, we made every effort to bring ourselves closer to you, our valued customers! 🌟 Here's a snapshot of our offline events: ✅ Attended 20+ conferences ✅ Organized and participated in 10+ workshops ✅ Hit the road with 15+ roadshows A big thank you to our incredible team, who made all these events possible. We sincerely thank their hard work and dedication, making every interaction meaningful. Together, we continue to innovate and grow! #CustomerConnection #Teamwork #Innovation

The FASTA format is a widely used standard in bioinformatics for representing and storing biological sequence data, using single-letter codes to denote nucleotides (DNA and RNA) and amino acids (proteins). FASTA files serve as inputs for various bioinformatics tools and workflows, including sequence alignment, genome assembly, annotation, and database searches. The format is highly valued for its simplicity and compatibility with database storage and retrieval systems. #ScienceFans #ScienceChallenge #ScienceCommunity