Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut

Thanks to all participants and visitors of #LNDWJena 🌃 at the Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut. It was a pleasure for us. We look forward to the next #LNDWJena 2026 👨🔬 👩💼 . Here are some impressions. #Science #ScienceCommunication

📢 Job alert! Several positions available at our Institute. Please visit https://lnkd.in/eRwXrpgu to see all vacancies.

Fighting antibiotic resistance with synthetic biology: #SynThera is a research project of the Friedrich-Schiller-Universität Jena funded by Carl-Zeiss-Stiftung that focuses on the development of personalized synthetic therapeutic microbes. These microbes are specifically designed to recognize and fight antibiotic-resistant pathogens with minimal side effects. The project is centered around a modular approach that aims to design microorganisms that recognise pathogens and render them harmless in a highly specific and locally limited way. “SynThera” is coordinated by Prof. Dr. Miriam Agler-Rosenbaum, head of our Bio Pilot Plant, and Prof. Dr. Kai Papenfort, Professor for General Microbiology at the University of Jena. The #LeibnizHKI is a major participant in this joint research project. The team came together at our institute to celebrate the successful start of “SynThera”. Read more about it here: https://lnkd.in/grtnD4VK Luzia Gyr Gianni Panagiotou Pierre Stallforth Christian Hertweck Rosalind Allen Ute Hellmich Hans-Dieter Arndt Balance of the Microverse Jena School for Microbial Communication ChemBioSys Leibniz-Zentrum für Photonik in der Infektionsforschung (LPI) #NewProject #SyntheticBiology #SyntheticMicrobes #AntibioticResistance #AMR #InfectiousDiseases #PersonalizedTherapy #GeneticEngineering #BioEngineering #SmartTherapeutics #NextGenMedicine #AntibioticCrisis #PathogenTargeting #Microbes #FSUJena #UniJena

Tonight is the night! 🔬 🌠 At the #LNDWJena you can learn exciting things from the world of microbiology. The #LeibnizHKI team is waiting for you! 📍 Location: Hermann-Löns-Straße 70, 07745 Jena 🗓 Date: Today 🕕 Time: 6 PM – Midnight 🌃

Congratulations to Shyam Krishnan from our Microbial Immunology team! 🎉 He was awarded 1st place for the best poster presentation at the General Assembly of the Leibniz PostDoc Network for “Fungal Foes: Immune Battles in Tumor” and was also elected as one of the two new spokespersons for the network. Well done, Shyam! “Invasive fungal infections like aspergillosis and disseminated candidiasis have a high mortality rate over 30%, often due to inadequate immune responses from underlying diseases or their treatments. Our study investigates whether B cell lymphoma itself increases susceptibility to these infections,” he explains the still on-going study.

🔬 Drug-Resistant Fungi: A Growing Global Threat to Healthcare 🦠 The spread of multi-drug resistant fungi is an emerging crisis in healthcare. A recent study published in "The Lancet Microbe" reveals alarming insights into an outbreak of Candida parapsilosis, a yeast that poses serious risks to immunocompromised hospital patients. Led by Dr. Amelia Barber (Cluster of Excellence "Balance of the Microverse") and Dr. Grit Walth (National Reference Centre for Invasive Fungal Infections - NRZMyk at the Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut) the research uncovers: 📊 The Scale of the Problem - A single resistant strain caused 33 invasive infections in Berlin hospitals from 2018–2022. - This strain is closely related to others found in Canada, the Middle East, and East Asia, highlighting the global nature of this threat. 🔍 A Game-Changing Innovation To combat the spread, the team developed a new molecular typing method. This cost-effective and rapid approach, known as Multilocus Sequence Typing (MLST), allows hospitals to quickly identify and track outbreaks of C. parapsilosis without relying on costly genome sequencing. 💡 The Bigger Picture With drug-resistant fungi on the rise globally, this study emphasizes the urgent need for: - Improved diagnostics and outbreak containment. - Collaboration between clinics, researchers, and policymakers to address resistance. 👉 Read more: https://lnkd.in/dXVyR-eu #InnovationInScience

👩🔬 Today the 6th project meeting for the new Leibniz-Zentrum für Photonik in der Infektionsforschung (LPI) took place at the Leibniz-HKI. In five talk sessions and one poster session, our scientists presented new results and important steps of the many different work packages. 👨🏫 The intense discussions and the great work atmosphere reflects the interdisciplinary work and cooperation between the partner institutions Leibniz-Institut für Photonische Technologien, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut, Friedrich-Schiller-Universität Jena and Universitätsklinikum Jena. We look forward to the next meeting in spring 2025 when more and more research results and basic technologies are on their final straights. 🚀   The Federal Ministry of Education and Research is funding the establishment of the LPI since 2021 as a globally unique infrastructure for the development of light-based technologies in the fight against infectious diseases and future pandemics. Bundesministerium für Bildung und Forschung #Biophotonik #Photonik #LeibnizZentrum #Infektionsforschung #Innovation

Mark your calendar! 🗓️ In just one week, the Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut (Leibniz-HKI) opens its doors for the Long Night of Sciences 2024 in Jena. 🌃 Discover the tiny but captivating universe of microorganisms through experiment stations and have a look into our labs! 🦠🌌 👩🔬👨🏾🔬 This is a unique opportunity to meet our scientists, ask questions, and get inspired by their work. 📍 Location: Leibniz-HKI, building A7: Hermann-Löns-Straße 70, 07745 Jena 📅 Date: Friday, November 22, 2024 🕒 Time: 6 PM – Midnight Don't miss out on this event! 🔬✨ #LNDWJena #LangeNacht #Jena #ScienceForAll #LeibnizHKI

Within the frame of the JSMC Mentoring Program I had the opportunity to visit my mentor Swantje Behnken and her team at Bayer in Leverkusen. 🌱 👩🔬 It was amazing to visit the Chempark and see the different types of labs and facilities available to the Bayer team. But what impressed me the most was the welcoming atmosphere and everyone taking so much time to answer my questions. Connecting with so many new and interesting people was amazing! I am particularly grateful for all the valuable experiences and career advice shared by these experts and group leaders. Huge thanks to the Jena School for Microbial Communication as well for making this possible by implementing a mentoring program and for funding my visit with a JSMC Travel Grant. This visit really made me ready and excited to tackle my next professional transition from academics to industry! 🚀

☎️🔔 Ring ring, we got something to share with you … 🧐 We suggest that RNA:DNA triplexes might play a big role in microbial communication! Holger Bierhoff and Amelia Barber from Friedrich-Schiller-Universität Jena and Matthew Blango from #LeibnizHKI propose a fascinating hypothesis in the American Society for Microbiology journal #mBio: Could RNA triplexes act as a communication tool between microbes and their hosts? 🤔💬 Historically seen as a mere messenger, #RNA is now recognized for its regulatory roles. This new perspective suggests that microbes might manipulate host gene expression through RNA #triplexes, potentially affecting immune responses and offering evolutionary advantages. 🧬🔄🦠 The researchers now urge the scientific community to further explore this promising area. 🧪💻 Discover more about their hypothesis in mBio: https://lnkd.in/endz76_k ... or in our own article: https://lnkd.in/eZvkWQYQ 📚🔍 Bundesministerium für Bildung und Forschung Deutsche Forschungsgemeinschaft (DFG) - German Research Foundation Leibniz-Gemeinschaft Balance of the Microverse #opinion #paper #hypothesis #RNA #DNA #triple #helix #epigenetics #microbes #host #microbial #communication #pathogenesis #fungi #microbiology