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A review of the efficacy of mycotoxin detoxifying agents used in feed in light of changing global environment and legislation

In: World Mycotoxin Journal
Authors:
E. Wielogórska Institute for Global Food Security, Queen’s University Belfast, 18-30 Malone Road, Belfast BT9 5BN, United Kingdom

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S. MacDonald Food and Environment Research Agency, Sand Hutton, York YO41 1LZ, United Kingdom

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C.T. Elliott Institute for Global Food Security, Queen’s University Belfast, 18-30 Malone Road, Belfast BT9 5BN, United Kingdom

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In the recent years, mycotoxins have undoubtedly gained a keen interest of the scientific community studying food safety. The main reason is their profound impact on both human and animal health. International surveys reveal a low percentage of feed samples being contaminated above permitted/guideline levels, developed to protect consumers of animal derived products. However, the deleterious impact of feed co-contaminated at low levels with numerous both known and regulated as well as novel mycotoxins on producing animals has been described. Associated effects on agro-economics world-wide include substantial pecuniary losses which are borne by the society as a whole. Even though good agronomic practice is thought to be the most effective way of preventing animal feed contamination, the EC have recognised the need to introduce an additional means of management of feed already contaminated with low-levels of mycotoxins to alleviate detrimental effects on agricultural production efficiency. This review discusses types of feed detoxifying agents described in scientific literature, their reported efficacy in bothin vitro andin vivo systems, and comparison with available commercial formulations in the light of increasing knowledge regarding mycotoxin prevalence in the changing global environment.

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