Nucleome Informatics Pvt Ltd

Small RNA and miRNA Sequencing Services by Nucleome Informatics Unlock the Power of Small RNA and miRNA with Next-Generation Sequencing Small RNA and microRNA (miRNA) play crucial roles in gene regulation, disease pathways, and cellular functions. At Nucleome Informatics, we offer high-quality Small RNA and miRNA Sequencing services to help researchers gain deep insights into gene expression, RNA silencing, and regulatory mechanisms across various biological systems. Why Choose Nucleome for Small RNA and miRNA Sequencing • Comprehensive Coverage: Detect and profile known and novel small RNAs, including miRNAs, piRNAs, siRNAs, and other regulatory RNAs • High Sensitivity and Accuracy: Our advanced sequencing platforms provide single-nucleotide resolution and precise quantification of low-abundance RNAs • Expert Bioinformatics Support: Our analysis pipeline includes miRNA discovery, differential expression analysis, pathway enrichment, and target prediction for functional insights • Customized Data Analysis: Receive publication-ready reports with detailed annotations, expression profiles, and interactive visualizations • End-to-End Workflow: From RNA extraction to data interpretation, we provide a seamless and reliable sequencing experience Applications of Small RNA and miRNA Sequencing • Cancer Research: Study tumor-suppressor and oncogenic miRNAs for biomarker discovery • Neuroscience: Investigate miRNA roles in neurodegenerative diseases and brain function • Agrigenomics: Explore plant miRNAs involved in stress responses, growth, and development • Drug Development: Identify miRNA-based therapeutic targets and biomarkers • Infectious Diseases: Understand host-pathogen interactions and immune responses Our Small RNA and miRNA Sequencing Workflow 1. Sample Preparation: High-quality RNA extraction and QC assessment 2. Library Preparation: Small RNA-specific library construction with adapter ligation and size selection 3. Next-Generation Sequencing: Ultra-high-throughput sequencing on Illumina NovaSeq 6000 for deep coverage 4. Bioinformatics Analysis • miRNA identification and quantification • Novel small RNA discovery • Differential expression analysis • Functional annotation and pathway analysis 5. Comprehensive Reporting: Interactive data visualization, pathway enrichment, and insights for publication Technical Specifications • Platform: Illumina NovaSeq 6000 • Read Length: 50 base pairs single-end or paired-end sequencing • Recommended Depth: 10 to 20 million reads per sample • Data Output: FASTQ files, expression matrices, annotation reports, and pathway analysis Get Started with Nucleome’s Small RNA and miRNA Sequencing services: Whether you are exploring novel small RNAs, investigating disease biomarkers, or analyzing gene regulation, our expert team ensures high-quality, reproducible results tailored to your research needs. Contact us today to discuss your project and get a customized quote. www.nucleomeinfo.com

Nucleome Informatics Pvt Ltd had the honor of hosting a distinguished delegation from Murdoch University, Australia. The visiting team included Prof. Rajeev Varshney, FRS, a globally renowned expert in agricultural genomics, Prof. Peter Davies, Pro Vice-Chancellor, and Prof. Joy Gilesnan, Business Manager at the Food Futures Institute. The delegation was warmly welcomed by Mr. Dushyant Singh Baghel, CEO of Nucleome Informatics, who presented them with flowers and a traditional Indian silk shawl as a token of appreciation. During their visit, the guests toured Nucleome’s state-of-the-art genomics lab, where they interacted with the company’s team of scientists and gained insights into its advanced research capabilities. The discussions centered around Nucleome’s 12-year journey, its contributions to genomics and bioinformatics, and its impact on agriculture and healthcare. Both Nucleome Informatics and Murdoch University expressed keen interest in exploring collaborative research opportunities in genomics and bioinformatics, particularly in areas that can drive innovation in agriculture and healthcare. This partnership aims to leverage cutting-edge sequencing technologies and data-driven approaches to enhance global scientific advancements. Commenting on the visit, Mr. Dushyant Singh Baghel said: “We are delighted to host esteemed researchers from Murdoch University. This visit marks the beginning of a promising collaboration that can lead to transformative research in genomics and bioinformatics, benefitting both India and Australia.” With aligned visions in advancing precision agriculture, genetic research, and personalized healthcare, Nucleome Informatics and Murdoch University look forward to fostering a strong partnership that will contribute to the global scientific community.

Unveiling a Novel Multidrug-Resistant Fish Pathogen with PacBio HiFi Sequencing A groundbreaking study led by Dr. Basanta Kumar Das (CIFRI) has identified a novel pathogenic and multidrug-resistant strain of Kytococcus sedentarius in Labeo rohita (rohu fish). This bacterium, part of the Micrococcales order, has a genome size of 2.59 Mb, 71.7% GC content, and carries 2,173 antimicrobial resistance genes, raising serious concerns about antibiotic resistance in aquaculture. Using HiFi sequencing, the genome was assembled into a single contig, providing a complete, high-accuracy representation of the entire chromosome. This achievement underscores the power of long-read sequencing in generating high-quality pathogen genomes, essential for disease management and antimicrobial resistance studies. Nucleome Informatics Pvt Ltd is proud to support this cutting-edge research, which strengthens genomic surveillance, pathogen detection, and sustainable aquaculture practices. Read the full study: https://lnkd.in/gtknvV6B #HiFiSequencing #Genomics #WholeGenomeSequencing #AntimicrobialResistance #Aquaculture #Fisheries #Microbiology #PathogenGenomics #SustainableFarming #CIFRI

Day 2 at the Asian Fisheries and Aquaculture Forum: Advancing Genomics in Aquatic Sciences The second day at the Asian Fisheries and Aquaculture Forum has been incredibly engaging, with thought-provoking discussions on the role of genomics in sustainable aquaculture. As we continue our journey at Nucleome Informatics, it’s inspiring to see how genomic insights can drive better disease resistance, selective breeding, and overall productivity in fisheries. Our conversations with researchers, industry leaders, and policymakers reaffirm the growing need for Next-Generation Sequencing (NGS) in aquatic sciences—from understanding genetic diversity to optimizing breeding programs. The potential to enhance food security and sustainability through precision aquaculture is vast, and we are excited to contribute to this transformation. Looking forward to more insightful sessions and collaborations as we explore how genomics can redefine the future of fisheries and aquaculture. If you’re at the forum, stop by our booth for a discussion on how we can work together to bring genomic solutions to this industry! #AFAF2025 #GenomicsInAquaculture #SustainableFisheries #NucleomeInformatics

Honored to Host Shri Rajiv Ranjan Singh (Lalan Singh) Ji at Nucleome’s Booth at the Asian Fisheries and Aquaculture Forum! We were privileged to welcome Shri Rajiv Ranjan Singh (Lalan Singh) Ji, Hon’ble Minister of Animal Husbandry, Dairying & Fisheries, along with Dr. Himanshu Pathak, DG, ICAR, at Nucleome Informatics’ booth during the Asian Fisheries and Aquaculture Forum Summit. Our team had insightful discussions on the role of genomics in aquaculture and livestock health, emphasizing how Next-Generation Sequencing (NGS) can enhance disease resistance, improve breeding programs, and drive sustainability in India’s fisheries and animal husbandry sectors. At Nucleome, we are committed to leveraging advanced genomics to support India’s growing aquaculture and livestock industries, ensuring healthier breeds, better yields, and sustainable practices. Looking forward to collaborating with government bodies, researchers, and industry leaders to drive innovation in this space! #Genomics #Aquaculture #Fisheries #AnimalHusbandry #SustainableFarming #NGS #NucleomeInformatics

Nucleome Informatics at the Asian Fisheries and Aquaculture Forum – Day 1! We are thrilled to be exhibiting at the Asian Fisheries and Aquaculture Forum, and the first day has already been a great success! We’ve had insightful discussions about how genomics is transforming fisheries and aquaculture, from whole genome sequencing to genetic selection for disease resistance and productivity. A key highlight to look forward to—our CEO, Dushyant Singh Baghel, will be a panellist on 14th February, sharing insights on how advanced genomics is shaping the future of sustainable aquaculture. If you’re attending the forum, visit our booth to explore how our genomics solutions can drive innovation in fisheries and aquaculture. Looking forward to more exciting conversations in the coming days! #Aquaculture #Fisheries #Genomics #SustainableFisheries #NucleomeInformatics #Innovation

🌿🔬 Genome Assembly of Plant, Animal, and Microbial Genomes – Join Us! 🧬🐟 We’re excited to bring together leading genomics experts to discuss cutting-edge advancements in genome assembly! This session will explore how HiFi sequencing, Optical Mapping, Hi-C, and Iso-Seq are transforming the assembly of high-quality plant, animal, fish, and microbial genomes. 🌱🦠🐠 📌 Key Takeaways: ✅ How HiFi sequencing enhances genome accuracy with long, high-fidelity reads ✅ Role of Optical Mapping in detecting structural variations and genome scaffolding ✅ Importance of Hi-C in chromosome-level genome organization ✅ How Iso-Seq refines genome annotation with full-length transcript sequencing ✅ Real-world case studies & best practices for integrating these technologies Whether you're in plant breeding, animal genetics, aquaculture, or microbial research, this session will equip you with actionable insights to enhance your genomic projects. 📅 Tuesday, March 18, 2025 ⏰ 3:00 PM - 4:45 PM 📍 The Westin Gurgaon – Nature 🔗 Don’t miss this opportunity to engage with global experts and stay ahead in the genomics revolution! Registration is mandatory: https://lnkd.in/gYMe9dkF #Genomics #GenomeAssembly #HiFiSequencing #OpticalMapping #HiC #IsoSeq #PlantGenomics #AnimalGenetics #MicrobialGenomics #Bioinformatics #FutureOfGenomics

Exciting Collaboration in Genomics & Precision Medicine! We are thrilled to announce that Nucleome Informatics and Sri Ramachandra Institute of Higher Education and Research (SRIHER) have signed a Memorandum of Understanding (MoU) to advance cancer genomics, cardiology, and rare genetic disorders such as Inherited Retinal Diseases (IRD). This partnership focuses on: ✅ Joint research in oncology, cardiology, and rare diseases ✅ Clinical genetic testing to improve patient care ✅ Training programs to equip students with advanced genomics expertise ✅ Shared facilities to drive collaborative research ✅ Development of translational products for real-world clinical applications Nucleome has already developed DrSeqIRD, a specialized genetic test for Inherited Retinal Diseases, and with this collaboration, we will extend our innovations to oncology and cardiology—bringing cutting-edge genomics closer to clinical practice. The MoU was formalized at the “Genomics and Precision Medicine in Cancer” event, where our CEO, Mr. Dushyant Singh Baghel, was the Guest of Honour, and Dr. Kalpana Balakrishnan, Dean of SRIHER, chaired the session. The event saw active participation from clinicians, researchers, and medical students, reflecting the growing synergy between academia, hospitals, and the genomics industry. We look forward to transforming healthcare with precision genomics and translational research! #Genomics #PrecisionMedicine #CancerGenomics #Cardiology #RareDiseases #ClinicalGenetics #TranslationalResearch #NucleomeInformatics #SRIHER #HealthcareInnovation

Join Us for an International CME on “Genomics and Precision Medicine in Cancer” We are thrilled to announce that Nucleome Informatics, in collaboration with Sri Ramachandra Institute of Higher Education and Research (SRIHER), is hosting an International Continuing Medical Education (CME) event focused on Genomics and Precision Medicine in Cancer. 📅 Date: 1st February 2025 🕘 Time: 9:30 AM onwards 📍 Venue: Lecture Hall 2, Medical College Building, SRIHER, Chennai This event will bring together leading experts, researchers, and clinicians to discuss groundbreaking advancements in omics technologies, precision oncology, multiomics, radiogenomics, AI-driven drug discovery, genetic counseling, and more. 🔹 Key Highlights: ✅ MoU Signing between SRIHER & Nucleome Informatics ✅ Expert talks on emerging genomics technologies ✅ Cutting-edge insights into cancer heterogeneity, inherited retinal disorders, liquid biopsies, and AI-driven precision medicine ✅ Speakers from Nucleome Informatics, Tata Cancer Hospital, Sankara Nethralaya, Prashanti Cancer Care, KIMS, Nalagenetics (Singapore), and Instant NanoBiosensors (Taiwan) We invite oncologists, geneticists, researchers, and healthcare professionals to join this knowledge-sharing platform and explore the future of personalized cancer treatment. 📝 Registration is free! Don’t miss out on this opportunity to network and learn from the best in the field. Registration is mandatory. Register here. https://lnkd.in/edHxMnC7 📢 Tag your colleagues, spread the word, and let’s advance precision medicine together! #Genomics #PrecisionMedicine #CancerResearch #CME #Oncology #NucleomeInformatics #SRIHER #HealthcareInnovation

On this Republic Day, let us celebrate the spirit of India—the land of diversity, resilience, and unity. May we continue to uphold the values of justice, equality, and liberty that form the foundation of our nation. Together, let’s strive to build a stronger and brighter future for all. Happy Republic Day! Jai Hind!