[en] To improve the water solubility of arylsulfonylimidazolidinone (JSH-2282), a potent anti-cancer agent, two urea derivatives, sodium S-2-3-4-5-S-2-oxo-4-phenylimidazolidin-1-ylsulfonyl indoline-1-carbonyl-phenyl ureido succinate (2a) and sodium S-2-3-4-5-S-2-oxo-4-phenylimidazolidin-1-ylsulfonyl indoline-1-carbonyl phenyl ureido pentanedioate (2b), were synthesized and studied for solubility and anti-cancer activity

[en] Methyl ethyl ketone and toluene in the off-gases of a plant producing polyvinyl chloride sheeting for the automotive industry and swimming pools caused frequent odour complaints from the neighbourhood. A pilot project was developed to investigate the removal of the compounds under actual operating conditions by passing part of the exhaust through a compost-based, three-stage biofilter. It was determined over the 156 days of operation that the removal efficiencies of methyl ethyl ketone and toluene averaged 73% and 49%, respectively. It was also shown that shutdowns and disruptions of the laminating process for short and extended periods did not affect the biofilter performance. Addition of 100g/L solution of KNO₃ as a nitrogen source did not improve the performance. Carbon dioxide concentration data and the presence of an average microbial population of 52 million colony forming units per gram provided evidence that biological degradation played a significant role in the reduction of methyl ethyl ketone and toluene in the off-gases of the laminator. (author)

[en] Separation rhenium 188 from tungsten 188 as a target by extraction method has been done to develop production of rhenium 188 radioisotope that fulfill radionuclide and radiochemical purity. This separation determination was by solvent extraction using methyl ethyl ketone (MEK). Prior to the separation process, it was determined beforehand the optimum conditions of extraction process based on the effect of agitation time, the volume of MEK, the pH of the solution, and distribution coefficient. Confirmation of the results of the extraction was conducted using UV Vis spectrophotometer with a complexing KSCN under acidic conditions and SnCl as reductor. The results showed that the optimum condition for extraction process to feed each of 10 ppm was as follows: agitation time 10 minutes, volume of MEK 20 ml, and the pH below 5. Maximum concentration of rhenium obtained at the organic phase was 9.5350 ppm. However, the condition of the extraction process did not affect the migration of tungsten to the organic phase. The maximum Dc value obtained was 2.7566 for rhenium and 0.0873 for tungsten. Optimum conditions of extraction process can be further tested on radioactive rhenium and tungsten as an alternative to the separation of radioisotopes. (author)

[en] The use of diketone ligands, such as hexafluoroacetylacetone (Hhfac) and tetramethylheptandione (Htmhd), can react in solvent-free and solvent-minimal routes to effect separation fission products from uranium matrices without any pre-preparation of the isotopes in question, and provides a path to drastically simplify the separations process and limits the potential for contamination and waste formation due to extensive handling, while increasing the rapidity of separation and isolation of target elements. In particular, the reactivity cesium, barium, strontium, silver, and lead with Hhfac can allow for rapid separations from uranium matrices such as oxide mixtures, in some cases in a matter of minutes. (author)

[en] We have designed a highly twisted small thermally activated delayed fluorescence (TADF) emitter PXZ-α-DK based on an α-diketone (α-DK) as a strong acceptor and phenoxazine (PXZ) as a strong donor to obtain red-shifted emission in comparison with the equivalent α-diketone linked to 9,9-dimethyl-9,10-dihydroacridine (DMAC). The PXZ-α-DK shows emission at 586 nm and DMAC-α-DK shows emission at 548 nm in 1,3-bis(N-carbazolyl)benzene (mCP) host at 1.5 wt% doping of the emitter, with short-delayed lifetimes of 6.9 μs for PXZ-α-DK and 7.6 μs for DMAC-α-DK. Organic light-emitting diodes (OLEDs) fabricated using these emitters show green electroluminescence at 555 nm for DMAC-α-DK, with a maximum external quantum efficiency, EQE_max, of 6.3%, and orange electroluminescence at 585 nm for PXZ-α-DK, with an EQE_max of 0.8%. We corroborate the optoelectronic properties of these emitters with DFT calculations. (author)

No abstract available

[en] Chemoselective methods for O- and N-nitration of steroids fused to the pyrazole ring were developed. The nitrating agents were acetyl, propionyl, and trifluoroacetyl nitrates generated from carboxylic acid anhydrides and either copper nitrate or nitric acid. Depending on the reaction conditions, the developed methods allow both selective nitration at the pyrazole nitrogen atom leaving intact the hydroxy group of steroid framework and dinitration giving rise to the corresponding nitrates of steroidal nitropyrazoles.

[en] The radiolytic decomposition of aqueous phase 2-butanone (methyl ethyl ketone (MEK)) has been studied extensively to gain a detailed mechanistic understanding of the effects of organic impurities on the behaviour of iodine in containment following a nuclear reactor accident. Based on the experimental results reported previously, a detailed reaction kinetic model for the steady-state γ-radiolysis of aerated aqueous solutions containing MEK has been developed. The model consists of about 130 radiolytic decomposition reactions in addition to about 25 water radiolysis reactions. The model reproduces the observed dose profiles of MEK and its subsequent decomposition products (3-hydroxy-2-butanone, acetaldehyde, acetic acid and formaldehyde) very well. The worst case was formaldehyde, a tertiary molecular product from MEK decomposition, which was still reproduced to within 50%. The model also reproduces the observed dose profile of pH reasonably well. The key reactions controlling the behaviour (or dose profiles) of MEK and its decomposition products and the sensitivity of their behaviour to the rates of these reactions are discussed. (author)

[en] This paper describes the group separation technique of a multi tracer from a gold target irradiated by high energy heavy ions. (author). 1 fig

No abstract available