[en] In this note an attempt is presented to show that: a) an operative analysis of the concept of distinguishability of identical particles leads to the conclusion that it is not applicable to the statistical description of a physical system; statistical thermodynamics would then require the concept of indistinguishability; b) by its own the concept of indistinguishability will require, when the Planck constant is properly introduced in the deductive analysis, the uncertainty correlation relation ΔqΔp>=h. (Author)

No abstract available

[en] The nonconventional thermodynamical approach to subatomic physics is described with large nonequilibrium effects taken into account by introducing the temperature continuum O≤T<∞. The approach is an expansion of the classical fluctuation theory and chemical-reaction formalism. A large body of problems in low- and high-energy nuclear physics is solved in the framework of super-nonequilibrium thermodynamics. 30 refs., 2 figs., 1 tab

[en] It is established that for CRISPR-Cas9 applications guide RNAs with 17–20 bp long spacer sequences are optimal for accurate target binding and cleavage. In this work we perform cell-free CRISPRa (CRISPR activation) and CRISPRi (CRISPR inhibition) experiments to demonstrate the existence of a complex dependence of CRISPR-Cas9 binding as a function of the spacer length and complementarity. Our results show that significantly truncated or mismatched spacer sequences can form stronger guide–target bonds than the conventional 17–20 bp long spacers. To explain this phenomenon, we take into consideration previous structural and single-molecule CRISPR-Cas9 experiments and develop a novel thermodynamic model of CRISPR-Cas9 target recognition. (paper)

No abstract available

No abstract available

[en] Short communication

[en] In this Letter it is proposed another generalization of the Verlinde's maps for the case Λ≠0. Thermodynamical arguments combined with this proposal conduce to a inverse square-law cosmological term behavior

[en] A thermodynamic dataset was developed for the central part of the Ce-O system covering the range between Ce₂O₃ and CeO₂ up to about 2000 K. All literature data for the thermodynamic functions, the phase diagram and crystallography were critically assessed. The modeling of the phases takes into account their crystal chemistry including order-disorder behavior. From the dataset, diagrams were calculated for the (1) heat capacities of CeO₂ and Ce₂O₃, (2) enthalpy increment of CeO₂, (3) chemical potentials of oxygen in CeO_2-x, (4) partial enthalpies of oxygen in CEO_2-x, (5) the partial phase diagram of Ce-O and (6) chemical potentials of oxygen in the two-phase areas. These diagrams reproduce fairly well the experimental data from literature. (orig.)

[en] Highlights: • A new method is proposed to solve the problem of height fluctuations. • A multi-node thermodynamic model of the airship is established. • The venting and inflation are considerably affected by the season and latitude. • Mesh refinement could have a slightly effect on the temperatures of the airbags. -- Abstract: A new fixed-point adjustment method for an airship is proposed to solve the problem of height instability due to dramatic daily-temperature swings. The airship membrane was discretized into a triangular element in this paper to enhance the computing accuracy of the method, and the multi-node thermodynamic model of the airship is established. The thermal performance of the airship is obtained using the Runge–Kutta method. The influences of season and latitude on the membrane, helium temperature and exhaust/inflation performance were investigated. The effect of the film elements on thermal performance is also discussed in detail. These results are helpful for the optimal design and operation of stratospheric airships.