[en] In this contribution, we present the results of PDF analyses coupled with other complementary experimental and theoretical approaches. From these results we have been able to show the influence of structural and textural organisation on the catalytic properties in Fe(at)SiO₂ nanocomposites. We will also discuss the effect of processing conditions on the interesting structural and physical properties of functionalized magnetite nanoparticles

[en] In the course of the last years, mesoporous bioactive glasses (MBGs) are increasingly used in the medical field, particularly for bone reparation and regeneration due to their biocompatibility and unique bioactive properties. Their bioactive properties are often determined by their ability to form and develop a bone-like apatite layer consisting of crystalline carbonate hydroxyapatite (HCA) on their surface when exposed to bodily fluids. We present a comparative study of the bioactive properties of two MBGs: 58S (60% SiO₂, 36% CaO, 4% P₂O₅ (mol. %)) and 70S30C (70% SiO₂, 30% CaO (mol. %)) prepared by optimized sol-gel method. For the study of their interactive mechanisms, we used two different physiological media, namely c-SBF (classic Simulated Body Fluid) and m-SBF (modified Simulated Body Fluid) with various interaction times. X-ray total scattering coupled with Pair Distribution Function (PDF) analysis, complemented by Raman spectroscopy and scanning electron microscopy, were used to monitor the formation and development of distinct species that form on the surface of bioglasses from the first hours of immersion in SBFs. The obtained results indicate the presence of different interaction mechanism between MBGs and physiological fluids, leading to the formation of additional phases like amorphous calcium phosphate and calcite, which evolve and can transform to HCA, depending on the soaking time, the MGB composition, as well as on the type of SBF

[en] With the aim of obtaining compounds with promising properties, our team has been interested in the synthesis of aromatic Schiff bases containing triazole groups, thus combining the properties of Schiff bases with those of triazoles. A large number of bases have been obtained and studied, varying the type of triazole and/or the substituents (hydroxyl or halogen). In this contribution we present the effect of the position of the hydroxyl substituents and the type of triazole on the structure of the compound, and their antifungal properties. Four mono- and disubstituted Schiff bases will be presented, along with their structures and antifungal properties. To complete the work, a molecular docking study was carried out on the sterol 14-alpha demethylase protein (pdb: 6CR2) because of its structure, based on the design of new antifungal drugs