No abstract available

[en] The chromatographic separation of D₂, O₂, N₂, CH₄, Co and CO₂ in He and the quantitative analysis method of D₂, O₂ and N₂ by GC are described. A 5A molecular sieve column and temperature program are used. The components of D₂, O₂, N₂ CH₄, CO and CO₂ in He can well be separated. He is used as carrier gas and TCD as detector, the respective sensitivities of D₂, O₂ and N₂ are measured. The sensitivity of N₂ is the highest in these components and the relative sensitivities of D₂ and O₂ compared with N₂ are 0.1 and 0.9, respectively. When the pressure of injected sample is 0.1 MPa and the volume is 0.5 ml, the detection limit of D₂ is 0.004%(n/n). The relative standard deviations are 1% for sample larger than 3%(n/n) component and 10% for 0.05%∼1%(n/n) component. This method can be used to monitor these impurities in helium blanket gas of a nuclear reactor

No abstract available

[en] Introduction: Dedifferentiated thyroid cancer is often incurable because it does not respond to radioiodine. This study aimed to investigate iodide uptake and the expressions of thyroid-specific molecules after the transfection of human thyrotropin receptor (hTSHR) gene in poorly differentiated follicular thyroid cancer cell line (FTC-133). Methods: pGC-FU-hTSHR-GFP-lentivirus and pGC-FU-GFP-lentivirus were added into FTC-133 cells respectively. The parental cells were defined as the blank group. Cells transduced with pGC-FU-GFP and pGC-FU-hTSHR-GFP were defined as the control group and experimental group respectively. The efficiency of transfection was observed under a fluorescence microscope. ¹²⁵I uptake by FTC-133 was analyzed by measuring the radioactivity. Real time-PCR, western blotting and radioimmunoassay were applied to detect the expressions of mRNAs and proteins of Na⁺/I⁻ symporter (NIS), thyroid-stimulating hormone receptor (TSHR), thyroid peroxidase (TPO) and thyroglobulin (Tg) in FTC-133. Results: The green fluorescence was present in 80% of the transduced cells under fluorescence microscope. The iodine uptake of cells transduced with pGC-FU-TSHR-GFP was 3.3 times higher than that in the other two groups (P < 0.01). NIS, TSHR, TPO and Tg had been significantly up-regulated in the experimental group as compared to the control group (P < 0.01) and the blank group (P < 0.01). Conclusion: The hTSHR transfection in FTC-133 improved the expression of thyroid-specific molecules including TSHR, NIS, TPO and Tg and radioiodide uptake

No abstract available

[en] A method called 'Two Arm's Photo out and Electricity Send-back' is introduced. UV-365 UV/VIS/NIR spectrophotometer has been reequipped by this way with 5 meters long optical fiber. Another method called 'One Arm's Photo out and Photo Send-back' is also introduced. λ₁₉ UV/VIS/NIR spectrophotometer has been reequipped by this way with 10 meters long optical fiber. Optical fiber spectrophotometer can work as its main set. So it is particularly applicable to radio activity work

[en] Early diagnosis and treatment are of paramount importance for pediatric patients with autoimmune encephalitis (AE). The aim is to evaluate the usefulness of FDG PET/CT in pediatric patients with suspected AE from a prospective study. The prospective study was conducted over a period of 23.5 months from May 14, 2019, to April 30, 2021. All patients (< 18-year-old) were hospitalized at the department of pediatric neurology and met the criteria of clinical suspected AE. The children underwent the tests of blood samplings, CSF, EEG, MRI, and ${}^{18}$F-FDG PET/CT. The criteria for FDG PET/CT diagnosis of AE were large lobar hypometabolism with or without focal hypermetabolism found on PET/CT. The clinical final diagnosis of AE includes seropositive and seronegative AE based on the diagnostic criteria. One hundred four pediatric inpatients (57 boys, 47 girls) were included, of which 58 children were diagnosed with AE (seropositive, 16; seronegative, 42), 45 children were diagnosed with non-AE, and one boy remained indeterminate diagnosis. Large lobar hypometabolism was found in 61 children, of which 54 (88.5%) children were finally diagnosed with AE. The sensitivity, specificity, and accuracy of FDG PET/CT for diagnosis of AE were 93.1%, 84.4%, and 89.3%, respectively, with a positive predictive value of 88.5% and a negative predictive value of 90.5%. The most common involved with hypometabolism was the parietal lobe, followed by occipital and frontal lobes, finally the temporal lobe on PET/CT in children with AE. Brain FDG PET/CT imaging has high specificity, sensitivity, and accuracy for diagnosis of AE in clinical suspected AE children.

[en] Vanadium dioxide (VO₂) coating plays an important role in energy saving and environmental protection due to its unique reversible phase transition. To solve the daylighting issue of VO₂ coating, a VO₂ (M)–silicon dioxide (SiO₂) composite coating is fabricated from ammonium citrato-oxovanadate(IV) by a SiO₂-assisted coating method. The VO₂ (M)–SiO₂ composite coating possesses excellent thermochromic properties that have produced varying results, i.e. 49.2% of visible transmittance, 52.3% of transmittance reduction at 2000 nm wavelength, 12% of solar energy modulation (ΔT _sol) and a phase transition temperature of 56.0 °C. Our findings may pave the way to extending the large-scale application of smart windows based on thermochromic VO₂. (paper)

[en] This work presents the development of flexible dual-mode surface acoustic wave (SAW) sensor based on single crystalline thin film lithium niobate (TF-LN). Numerical modeling is conducted to investigate the SAW propagation and the effects on strain sensitivity. The dependence of strain sensitivity on angles between the applied strain and SAW propagation direction is analyzed numerically and experimentally, showing that the maximum strain sensitivity is at 45° rather than longitudinal direction. 128° Y-cut TF-LN (∼50 µm), obtained by micromachining technique, is utilized as the piezoelectric substrate to fabricate the SAW strain sensors with dual-mode, namely Rayleigh mode and thickness shear mode. The sensor has excellent flexibility and demonstrates remarkable capability for an ultra-wide range strain measurement up to  ±3000 . Temperature effects on resonant frequency and strain sensitivity are investigated in the range of 25 °C–100 °C, and similar temperature characteristics are observed for the dual modes. A method of beat frequency between the dual modes is introduced which is able to eliminate the temperature effect on strain sensing, an on-chip temperature influence removing capability. All the results clearly show that this sensor exhibits great potential for applications in flexible electronics and microsystems. (paper)

[en] Highlights: • Triclosan (TCS) was detectable (> 0.1 ng/mL) in 97.9% of Chinese pregnant women. • Maternal TCS exposure is associated with higher risk of gestational diabetes mellitus, which may partially intermediated via maternal BMI. • Maternal TCS exposure is associated with higher birthweight among female infants. Triclosan (TCS) is an antibacterial chemical widely used in personal-care products and an endocrine disruptor. While TCS exposure is associated with insulin resistance and metabolic disorders in animals, few studies have assessed its effect on the risk of gestational diabetes mellitus (GDM) in humans. This study aimed to explore whether maternal urinary TCS level is associated with the risk of GDM and infant birthweight. We examined 620 pregnant women from Shanghai, China in 2012–2013. Urinary TCS level was measured with high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS), and categorized into high, medium and low in tertiles. GDM was defined based on recommendation of International Association of Diabetes and Pregnancy Study Groups (IADPSG). The GDM rate was 12.7%. TCS was detectable (≥0.1 ng/mL) in 97.9% women (median 2.7 ng/mL). There was a positive, but statistically non-significant association between urinary TCS levels and GDM (adjusted odds ratio 1.17; 95%CI: 0.99, 1.39, with each unit increase of log (TCS) ng/mL) with adjustment for urinary creatinine, maternal age, education, passive smoking, parity and prepregnancy BMI categories. 48.1% of infants were females. Birthweight was 122.8 g higher (95% CI: 13.9, 231.6 g) for female infants of women in high TCS (median 13.3 ng/mL) versus low TCS (median 0.77 ng/mL), with adjustment for urinary creatinine, prepregnancy BMI, GDM and other confounders. No association was found between maternal TCS and birthweight in male infants. These results suggested the potential for TCS to be associated with increased risk of GDM and a gender-specific association with higher birthweight among female infants in a population with widespread but moderate exposure to TCS.