[en] The purpose of this Analysis/Model Report (AMR) is to document the predictions and analysis performed using the Seepage Model for Performance Assessment (PA) and the Disturbed Drift Seepage Submodel for both the Topopah Spring middle nonlithophysal and lower lithophysal lithostratigraphic units at Yucca Mountain. These results will be used by PA to develop the probability distribution of water seepage into waste-emplacement drifts at Yucca Mountain, Nevada, as part of the evaluation of the long term performance of the potential repository. This AMR is in accordance with the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (CRWMS M andO 2000 [153447]). This purpose is accomplished by performing numerical simulations with stochastic representations of hydrological properties, using the Seepage Model for PA, and evaluating the effects of an alternative drift geometry representing a partially collapsed drift using the Disturbed Drift Seepage Submodel. Seepage of water into waste-emplacement drifts is considered one of the principal factors having the greatest impact of long-term safety of the repository system (CRWMS M andO 2000 [153225], Table 4-1). This AMR supports the analysis and simulation that are used by PA to develop the probability distribution of water seepage into drift, and is therefore a model of primary (Level 1) importance (AP-3.15Q, ''Managing Technical Product Inputs''). The intended purpose of the Seepage Model for PA is to support: (1) PA; (2) Abstraction of Drift-Scale Seepage; and (3) Unsaturated Zone (UZ) Flow and Transport Process Model Report (PMR). Seepage into drifts is evaluated by applying numerical models with stochastic representations of hydrological properties and performing flow simulations with multiple realizations of the permeability field around the drift. The Seepage Model for PA uses the distribution of permeabilities derived from air injection testing in niches and in the cross drift to stochastically simulate the 3D flow of water in the fractured host rock (in the vicinity of potential emplacement drifts) under ambient conditions. The Disturbed Drift Seepage Submodel evaluates the impact of the partial collapse of a drift on seepage. Drainage in rock below the emplacement drift is also evaluated

[en] Simultaneous observations of large Solar Energetic Particle (SEP) events by multiple spacecraft located near 1 AU during solar cycle 24 have shown an east-west asymmetry of the peak intensities of SEPs with respect to the source flare locations. Using the 2D improved Particle Acceleration and Transport in the Heliosphere (iPATH) model, we consider multiple cases with different solar wind speeds and eruption speeds of the Coronal Mass Ejections (CMEs) and fit the longitudinal distributions of time-averaged fluence by Gaussian functions in 8-, 24- and 48-hour respectively. The simulation results are compared with a statistical study of 28 3-spacecraft (SC) events. The east-west asymmetry shows a clear time-dependent and energy-dependent evolution. We suggest that the east-west asymmetry of SEP fluence (and peak intensity) is a consequence of the combined effect of an extended shock acceleration process and the evolution of magnetic field connection to the shock front. Our simulations show that the solar wind speed and the eruption speed of CMEs are essential factors for the east-west fluence asymmetry.

[en] A semi-analytical simulation method is proposed in this paper to assess system reliability of structures. Monte Carlo simulation with variance-reduction techniques, systematic and antithetic sampling, is employed to obtain the samples of the structural resistance in this method. Variance-reduction techniques make it possible to sufficiently simulate the structural resistance with less runs of structural analysis. When resistance samples and its moments determined, exponential polynomial method (EPM) is used to fit the probability density function of the structural resistance. EPM can provide the approximate distribution and statistical characteristic of the structural resistance and then the first-order second-moment method can be carried out to calculate the structural failure probability. Numerical examples are provided for a structural component and two ductile frames, which illustrate the method proposed facilitates the evaluation of system reliability in assessments of structural safety

[en] An important issue for the performance of underground nuclear waste repositories is the rate of seepage into the waste emplacement drifts. A prediction of this rate is particularly complicated for the potential repository site at Yucca Mountain, Nevada, because it is located in thick, unsaturated, fractured tuff formations. Underground opening in unsaturated media might act as capillary barriers, diverting water around them. In the present work, they study the potential rate of seepage into drifts as a function of the percolation flux at Yucca Mountain, based on a stochastic model of the fractured rock mass in the drift vicinity. A variety of flow scenarios are considered, assuming present-day and possible future climate conditions. They show that the heterogeneity in the flow domain is a key factor controlling seepage rates, since it causes channelized flow and local ponding in the unsaturated flow field

[en] The concrete-filed square steel tube with inner I-shaped CFRP profiles short columns under bi-axial eccentric load were investigated by the finite element analysis software ABAQUS. The working mechanism of the composite columns which is under bi-axial eccentric load are investigated by using the stress distribution diagram of steel tube concrete and the I-shaped CFRP profiles. In this paper, the main parameters; eccentric ratio, steel ratio, steel yield strength, concrete compressive strength and CFRP distribution rate of the specimens were investigated to know the mechanical behavior of them. The interaction between the steel tube and the concrete interface at different characteristic points of the composite columns were analyzed. The results showed that the ultimate bearing capacity of the concrete-filed square steel tube with inner I-shaped CFRP profiles short columns under bi-axial eccentric load decrease with the increase of eccentric ratio, the ultimate bearing capacity of the composite columns increase with the increase of steel ratio, steel yield strength, concrete compressive strength and CFRP distribution rate. The contact pressure between the steel tube and the concrete decreased from the corner zone to the flat zone, and the contact pressure decreased from the mid-height cross section to other sections. (Author)

[en] A YBCO thick film containing 20 percent Ag2O with a T_c of 86.8 K and J_c of 108 A/sq cm was obtained. The film was fabricated by a two-step firing process, i.e., firing the film at 1000 C for 10 minutes and annealing at 970 C for 30 minutes. The two-step firing process, however, was not suitable for the multiple-lead YBCO sample due to the formation of the 211 green phase at 1000 C in the multiple-lead YBCO sample. A BSCCO thick film printed on a MgO coated MSZ substrate and fired at 845 C for 2 hours exhibited a superconducting behavior at 89 K. Because of its porous microstructure, the critical current density of the BSCCO thick film was limited. This report also includes the results of the YBCO and BSCCO materials used as oxide electrodes for ferroelectric materials. The YBCO electroded PLZT showed higher remanent polarization and coercive field than the sample electroded with silver paste. A higher Curie temperature for the PLZT was obtained from the YBCO electroded sample. The BSCCO electroded sample, however, exhibited the same Curie temperature as that of a silver electroded sample. Dissipation factors of the ferroelectric samples increased when the oxide electrode was applied

[en] MRI has excellent soft tissue contrast and can provide both anatomical and physiological information. It is becoming increasingly important in radiation therapy for treatment planning, image-guided radiation therapy, and treatment assessment. It is critically important at this time point to educate and update our medical physicists about MRI to prepare for the upcoming surge of MRI applications in radiation therapy. This session will review important basics of MR physics, pulse sequence designs, and current radiotherapy application, as well as showcase exciting new developments in MRI that can be potentially useful in radiation therapy. Learning Objectives: To learn basics of MR physics and understand the differences between various pulse sequences To review current applications of MRI in radiation therapy.To discuss recent MRI advances for future MRI guided radiation therapy Partly supported by NIH (1R21CA165384).; W. Miller, Research supported in part by Siemens Healthcare; G. Li, My clinical research is in part supported by NIH U54CA137788. I have a collaborative research project with Philips Healthcare.; J. Cai, jing cai

[en] Previous investigators have demonstrated synergistic interaction between hyperthermia and radiation or Adriamycin (ADR), using cell lines that are sensitive to heat or ADR alone. The authors investigated the effect of heat, radiation or ADR on Chinese hamster fibroblasts (HA-1), their heat resistant variants and their ADR resistant variants. Heat for ADR resistance did not confer cross resistance to radiation. Cells resistant to heat did show cross resistance to ADR. While cells selected for ADR resistance were not cross resistant to heat, they did not exhibit drug potentiation by hyperthermia, characteristic of ADR sensitive cells. Cytofluorometric measurement showed decreased ADR uptake in both heat and ADR resistant cells. The possibility of cross resistance between heat and ADR should be considered when designing combined modality trials

No abstract available

[en] YBa₂Cu₃O_7-δ (YBCO) and Sm partially substituted YBCO melt-textured (MT) bulks were grown by a novel seed of NdBa₂Cu₃O_7-δ (NdBCO) thick film. On the basis of experimental results in this work, the seed size effects on the formation of the domain structure were discussed. In addition, the melting process of the NdBCO thick film was in situ observed by high-temperature optical microscopy. It was found that the NdBCO LPE thick film decomposed incompletely after 30 min holding at 1100 deg. C, which is higher than processing temperatures of experiments. In short, due to its close lattice match, achievable large size and high thermal stability, the Nd123 thick film may be a good candidate for seeding REBCO growth