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AbstractAbstract
[en] This paper is a review of current data on the risks associated with human exposure to ionizing radiation. We examine these risks for dose levels ranging from very high (atomic bomb survivors) to very low (background). The principal end point considered is cancer mortality. Cancer is the only observed clinical manifestation of radiation-induced stochastic effects. Stochastic effects are caused by subtle radiation-induced cellular changes (DNA mutations) that are random in nature and have no threshold dose (assuming less than perfect repair). The probability of such effects increases with dose, but the severity does not. The time required for cancer to develop ranges from several years for leukemia to decades for solid tumors. In addition to somatic cells, radiation can also damage germ cells (ova and sperm) to produce hereditary effects, which are also classified as stochastic. However, clinical manifestations of such effects have not been observed in humans at a statistically significant level
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1996; 6 p; Winter meeting of the American Nuclear Society (ANS) and the European Nuclear Society (ENS); Washington, DC (United States); 10-14 Nov 1996; CONF-961103--12; CONTRACT W-7405-ENG-36; Also available from OSTI as DE96014041; NTIS; US Govt. Printing Office Dep
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