[en] Results of the uranium-zirconium system are summarized. Analysis of contribution of temperature dependence of thermodynamical multiplier to activation energy of mutual diffusion is presented. It is shown that depending on the character of the system from the ideal one this value may by loss of thermodynamical stability essentially decrease or increase the activation energy of mutual diffusion. The regularities related to the uranium-zirconium system were used for interpretation of results on diffusion in the anomalous metals (Zr, Hf, Ti)