[en] Objective: To analyze the geographical distribution of mortality from lung cancer in Uruguay, using spatial autocorrelation indicators, in order to identify regions of high and low risk in the period 1989-2008. Methodology: 1989-2008 interval was analyzed by grouping the data in the following periods: 1989-1991,1992-1994,1995-1997,1998-2000,2001-2003 and 2004-2008. As indicator risk S MR (Standardized Mortality Ratio) was used, with reference to the country as a entirety. The analysis was performed by calculating the index I and correlation plots space (both methods according Mo ran) for each period and the corresponding maps. The significance was determined by permutations, considering level 0.05 significance. Results: The results of the correlation coefficients for different periods were, in Men: 1989 -1991 (R = 0.29, p <0.05), 1992 -1994 (I = 0.11, N S), 1995 -1997 (R = 0.31, p <0.05); 1998 - 2000 (R = 0.24, p <0.05); 2000 - 2003 (R = 0.19, p <0.05); 2004 -2008 (R = 0.24, N S). In women: 1989 -1991 (R = -0.18, N S), 1992 -1994 (R = -0.16, N S), 1995-1997 (I = 0.18, N S); 1998 - 2000 (R = 0.06, N S); 2001-2003 (R = -0.16, N S), 2004 -2008 (I = 0.02, N S), 1989-2003 (R = -0.03, N S). Men in those departments where they met more risks Artigas were low (SM R = 0.52; 0.57; 0.61; 0.61; 0.60; 0.69), Salto (SM R = 0.52; 0.57; 0.58; 0.68; 0.76; 0.75), Black River (SM R = 0.69; 0.73; 0.76; 0.93; 0.73; 1.29) and Paysandu (SMR = 0.87; 0.85; 0.96; 0.79; 0.89; 0.92) in the respective periods. In women the 0.55; 0.78) Also, in the respective periods. Given the low number of cases in women the period 1989-2003 was also considered together to obtain one SMR Black River = 0.63 and jumped SMR = 0.68. Conclusions: In men, the existence of spatial autocorrelation was identified statistically significant, with stable results in the last 2 decades analyzed. This was not observed in women. The results found in males suggest the existence a region of lower mortality from lung cancer country located on the coast