Human Supplement: Postbiotics Full-Spectrum Metabolite Complex. and Regenerative Agriculture: Soil remediation using microbiome therapy of unparalleled quality. Astrobiome® is pioneering the intersection of space research and sustainable agriculture, developing space-enhanced bio-fertilizers, with the mission to revolutionize microbiome-farming on Earth and beyond.
Lien externe pour Astrobiome Space, SARL
Luxembourg, LU
Houston, US
Astrobiome Space, SARL a republié ceci
Gut-Brain Axis R&D Scientist | Scientific Lead & Project Manager | Healthy Aging | Neuroscience | Nutrition & Health | Science Translation & Strategic Innovation
Altered food liking in depression is driven by macronutrient composition | Lilly Thurn, Corinna Schulz, Diba Borgmann, Johannes Klaus, Sabine Ellinger, Martin Walter, Nils B. Kroemer https://lnkd.in/eC5Wh2FA
With the side-support Postbiotic treatment of #Astrobiome https://astrobiome.space #ozempic consumption may be a lot safer!
Researcher| Gut microbiome! Talks about #Gut-Brain #microbiota, #Nutrients, #Cancer * Magic Microbiome: Personalized Medicine Starts in Your Gut. * Happy Colon, Balanced Life Starts Here!
⚠️ #Ozempic (#Semaglutide): A Game-Changer in #Diabetes and #Obesity Management – But at What Cost⁉️ ✅Ozempic, a #GLP-1 receptor agonist made by Novo Nordisk. 🟢Originally approved for type 2 diabetes management; now also used for weight management and cardiovascular risk reduction. ✅Ozempic may exacerbate anabolic resistance, particularly in #aging and obesity, accelerating muscle loss and increasing the risk of #sarcopenic obesity. 🟢Chemical Modifications: Enhancements like attaching fatty acid chains improve its stability and duration in the body. ✅Rapid weight loss with Ozempic can lead to significant lean body mass (LBM) loss, often exceeding the ‘Quarter FFM Rule’ (20–40% of weight loss from fat-free mass), negatively impacting muscle strength and function. ✅Adequate daily protein intake (0.8–1.0 g/kg BW/d) is insufficient to counteract this loss. Higher intake (1.2–1.6 g/kg BW/d) from high-quality sources like whey and casein are necessary. ✅Ozempic is also linked to reduced bone mineral density (BMD) at the spine and hip, increasing fracture risk, thus requiring countermeasures such as calcium and vitamin D3 supplementation. ✅To mitigate muscle and bone loss, high-quality, protein-based multi-ingredient supplementation (whey/casein, creatine, calcium, vitamin D3, fish oil), along with resistance exercise and daily physical activity, are recommended. ✅Clinicians should monitor LBM and bone health in patients on Ozempic, particularly in older adults or those with metabolic syndrome, adopting a tailored approach to optimize musculoskeletal health. 🔷Semaglutide, the active ingredient in Ozempic, may influence #gut #microbiota composition. 🔹Semaglutide administration mitigated high-fat diet-induced microbial #dysbiosis, notably; ⬆️ beneficial bacteria like #Akkermansia, #Faecalibaculum, and #Allobaculum, ⬇️ #Lachnospiraceae and #Bacteroides. 🔹The gut microbial community can predict semaglutide treatment effects based on changes in clinical markers. 🔹Semaglutide and empagliflozin are associated with gut microbiome alterations throughout antidiabetic therapy, even if changes arose due to the indirect effects of T2D treatment, e.g., decreased BMI and HbA1c. 📍Clinical Benefits ♦️Type 2 Diabetes Management: Improves blood sugar control. ♦️Weight Management: Approved for long-term use in adults with obesity or weight-related comorbidities. ♦️Cardiovascular Protection: Shown to reduce the risk of heart attack, stroke, and cardiovascular death in at-risk populations. 🔔The Controversy: 🔴Gastrointestinal Issues: Common side effects include nausea, vomiting, and diarrhea. 🔴Carcinogenic Risk: FDA boxed warnings highlight the potential for thyroid C-cell tumors, based on animal studies. However, human relevance remains uncertain. 🔴Thyroid Cancer Link? Ongoing research explores whether semaglutide specifically increases thyroid cancer risk. 🖇️For access to more data please check my first comment.
Introducing Astrobiome Postbiotics! https://lnkd.in/gfK3Z498
Are Postbiotics the Future? I Think So. For years, probiotics have been the undisputed champions of gut health. We’ve seen them dominate yogurt aisles, supplement shelves, and marketing campaigns. But while probiotics have had their moment in the spotlight, I believe a new contender is emerging—one that could eventually overtake them in popularity. Enter postbiotics. Unlike probiotics, which are live bacteria, postbiotics are inactivated microorganisms that are capable of conferring a health benefit to the host. While this goes against conventional logic, the science is CLEAR. Postbiotics offer incredible benefits, often times as good or even better than their probiotic counterparts. And the best part? Postbiotics don’t require refrigeration, they have higher stability, and they offer consistent, targeted benefits without the viability concerns that can sometimes plague probiotics. 💡 Why does this matter? Because the future of gut health isn’t just about dumping live bacteria into our system and hoping they thrive. It’s about precision nutrition—delivering the exact bioactives our bodies need, without the variability of strain survival or individual gut differences. We’re already seeing major movement in this space, with postbiotics making their way into supplements, functional foods, and even skin health applications. And as consumer awareness grows, I wouldn’t be surprised if, one day, people start asking: "Wait… why take the live bacteria when I can go for an ingredient that doesn't require refrigeration, doesn't require overage, and offers all the same gut health and beyond benefits?" The gut health revolution is far from over—it’s just evolving. Who else sees postbiotics becoming the next big thing? Let’s discuss! 👇 #Postbiotics #GutHealth #FutureOfWellness #MicrobiomeScience #Probiotics #Innovation #novel #gutaxis #dietarysupplements #nutraceuticals
Astrobiome Space, SARL a republié ceci
Bacteria inside our organs are not just invaders but permanent residents This study recently published (https://lnkd.in/epqbUx4n) explores a fascinating discovery: our visceral organs host a unique microbiome residing within their cells: - Gram-negative bacteria are primarily found in the nucleus, while Gram-positive bacteria are in the cytoplasm. - These microbes are not just transient visitors but inherent inhabitants, they're present even in newborns and fetuses, independent of the gut microbiome. - The diversity of this cellular microbiome surpasses that of the gut, challenging traditional beliefs about sterile internal environments. This research highlights a revolutionary concept: our organs may rely on a "hidden microbiome" for functions we have yet to fully understand. Could this discovery redefine how we approach treatments, from cancer therapy to chronic disease management? #Microbiome #CellularBiology #PrecisionMedicine #HealthTech
Astrobiome Space, SARL a republié ceci
Pioneer in masterplanning human destinations on Mars 🔴, creator of Astrobiome Space a preeminent microbiome solution for human longevity and precision agriculture 💫. Top 100 Women in Aerospace & Aviation TFO Linkedin.
It is truly satisfying to see people's health can change for the better and their day-to-day experiences are more enjoyable! Some of my friends hopelessly thought to have terminal illnesses (from long chronic sinus infections to IBS to long-COVID brain fog...) Please read their reviews on Astrobiome Space, SARL https://lnkd.in/g-b5MgDr Let's start the year with no coughing!
Astrobiome Space, SARL a republié ceci
On a Mission to SAVE the Microbiome from Extinction | Founder & CEO at SwipeBiome & The Microbiome Mavericks
Experts Consensus On Microbiome Diagnostics and Therapeutics: Three Major Publications That You Shouldn't Miss Reading #Mysummary It took me some time to make a consensus within the consensus - but when you go through the slides it will make sense to you as well! #Mythoughts Consumers and patients who turn to direct-to-consumer (D2C) microbiome tests or rely on probiotics as therapeutics are often seeking solutions to pressing health concerns, hoping for clarity and actionable guidance. The last thing they need is a test that is incomprehensible, provides results with no clear application, or fails to improve their well-being. As a scientific and medical community, we have a responsibility to deliver reliable, accessible, and impactful tools that empower individuals to take meaningful steps toward better health. We must do better. HAPPY to hear your THOUGHTS and stay POSITIVE! #Myinspiration “Much of the best work of the world has been done against seeming impossibilities.” Dale Carnegie #microbiome #science #biology #health #pharma #diet #nutrition #probiotics #therapeutics #startup #biotech Joel DORE Céline Druart Harry Sokol Nicola Segata Eran Elinav John Cryan
Astrobiome Space, SARL a republié ceci
Are we ever too old for healthy aging? Aging is often accompanied by metabolic decline, which can limit the effectiveness of longevity treatments in later years. But new insights published recently in nature (https://lnkd.in/eQgCxmTz) suggest it’s not all bad news. While stress-inducing interventions like fasting, exercise, and certain drugs (e.g., metformin) show reduced benefits in older individuals due to mitochondrial inefficiency, other treatments shine regardless of age. NAD+ boosters, rapamycin, and Polymerase I inhibitors directly target metabolic stress and energy exhaustion, offering hope for meaningful health improvements even late in life. This research underscores the importance of tailoring longevity strategies to the individual. What works for younger individuals might need adjusting for older adults to focus on stress reduction and energy conservation rather than stress adaptation. #LongevityScience #HealthyAging #MetabolicHealth #PersonalizedMedicine
Astrobiome Space, SARL a republié ceci
What your oral health says about your stomach Recent research into the oral–gastric microbial axis (https://lnkd.in/epcDkaZ8) reveals a fascinating connection: oral microbes don’t just stay in your mouth—they travel to your stomach, influencing gastric health. For example, oral bacteria like Streptococcus anginosus and Prevotella melaninogenica can reach the stomach and contribute to inflammation, precancerous lesions, and even gastric cancer. This migration is linked to factors like poor oral hygiene and lifestyle choices, emphasizing the need to look at oral health as more than just a local issue. The implications are profound. Maintaining oral health—through regular brushing, flossing, and dental visits—might also reduce the risk of serious gastric diseases. It’s another reminder of the intricate connections within our bodies and the importance of preventive care. What’s your perspective on the oral-gut connection? Let’s discuss! #OralHealth #GutHealth #MicrobiomeResearch #PrecisionMedicine
Astrobiome Space, SARL a republié ceci
Visionary, Strategy & Innovation enabler | LinkedIn Top Voice, Influencer, Blogger, Speaker | Startup> Guru, Founder, Advisor, Board Member | Fortune 500 Trainer | Looking for Visionaries!
𝗘𝗺𝗯𝗿𝗮𝗰𝗶𝗻𝗴 𝗦𝗽𝗮𝗰𝗲-𝗔𝗴𝗲 𝗛𝗲𝗮𝗹𝘁𝗵: 𝗔𝘀𝘁𝗿𝗼𝗯𝗶𝗼𝗺𝗲® 𝗔𝗻𝗱 𝗧𝗵𝗲 𝗙𝘂𝘁𝘂𝗿𝗲 𝗢𝗳 𝗪𝗲𝗹𝗹𝗻𝗲𝘀𝘀 𝘼𝙨𝙩𝙧𝙤𝙗𝙞𝙤𝙢𝙚® 𝙞𝙨 𝙖 𝙥𝙞𝙤𝙣𝙚𝙚𝙧 𝙞𝙣 𝙨𝙩𝙚𝙡𝙡𝙖𝙧 𝙢𝙞𝙘𝙧𝙤𝙗𝙞𝙤𝙢𝙚 𝙩𝙝𝙚𝙧𝙖𝙥𝙞𝙚𝙨, introducing postbiotic supplements engineered with NASA-inspired biotechnology. Derived from the super-centenarian microbiome of the world’s Blue Zones, Astrobiome® is redefining health optimization by blending ancient fermentation methods with cutting-edge space science. 👉 𝗔𝘀𝘁𝗿𝗼𝗯𝗶𝗼𝗺𝗲®'𝘀 𝗦𝗼𝗹𝘂𝘁𝗶𝗼𝗻: Astrobiome® delivers a full-spectrum metabolite complex packed with over 600 active compounds that enhance micronutrient production in the body. Available in powder, liquid, and tablet forms, these postbiotics are clinically proven to improve digestion, hormone balance, detoxification, brain performance, and immune health, all without side effects. 👉 𝗗𝗶𝘀𝗿𝘂𝗽𝘁𝗶𝘃𝗲 𝗨𝘀𝗲 𝗖𝗮𝘀𝗲𝘀: 🔸 𝑯𝒊𝒈𝒉-𝑷𝒆𝒓𝒇𝒐𝒓𝒎𝒂𝒏𝒄𝒆 𝑶𝒑𝒕𝒊𝒎𝒊𝒛𝒂𝒕𝒊𝒐𝒏: Support astronauts, military personnel, and elite athletes with enhanced resilience and recovery. 🔸 𝑮𝒍𝒐𝒃𝒂𝒍 𝑯𝒆𝒂𝒍𝒕𝒉: Tackle chronic diseases like diabetes, obesity, and cardiovascular conditions with affordable, scalable postbiotic solutions. 🔸 𝑺𝒑𝒂𝒄𝒆 𝑬𝒙𝒑𝒍𝒐𝒓𝒂𝒕𝒊𝒐𝒏: Develop gut health solutions for humans thriving in extreme environments like the Moon and Mars. 👉 𝗪𝗵𝘆 𝗔𝘀𝘁𝗿𝗼𝗯𝗶𝗼𝗺𝗲® 𝗶𝘀 𝗩𝗶𝘀𝗶𝗼𝗻𝗮𝗿𝘆: Astrobiome® represents the future of human health by addressing the “silent pandemics” caused by food industrialization. Its space-inspired innovations are not only improving health on Earth but also laying the foundation for sustainable life in space. With its focus on both planetary and space-based applications, Astrobiome® is a true bridge between the ancient wisdom of microbiome science and the limitless potential of human exploration. 👉 𝗦𝘂𝗽𝗽𝗼𝗿𝘁 𝗔𝘀𝘁𝗿𝗼𝗯𝗶𝗼𝗺𝗲®: 𝗪𝗲𝗯: https://lnkd.in/gz8Dq92v LinkedIn: Astrobiome Space, SARL 🚀 𝐃𝐎 𝐘𝐎𝐔 𝐇𝐀𝐕𝐄 𝐀 𝐓𝐄𝐂𝐇 𝐏𝐑𝐎𝐃𝐔𝐂𝐓 𝐓𝐎 𝐁𝐑𝐈𝐍𝐆 𝐈𝐍𝐓𝐎 𝐓𝐇𝐄 𝐌𝐀𝐑𝐊𝐄𝐓? ✉ 𝐂𝐎𝐍𝐓𝐀𝐂𝐓 𝐌𝐄! ----------------------------------------------------------------------- 🔔 𝘏𝘪𝘵 𝘵𝘩𝘦 𝘣𝘦𝘭𝘭 𝘵𝘰 𝘤𝘢𝘵𝘤𝘩 𝘮𝘺 𝘯𝘦𝘹𝘵 𝘱𝘰𝘴𝘵 💡 𝘓𝘪𝘬𝘦 𝘢𝘯𝘥 𝘴𝘩𝘢𝘳𝘦 𝘵𝘰 𝘴𝘱𝘳𝘦𝘢𝘥 𝘷𝘪𝘴𝘪𝘰𝘯𝘢𝘳𝘺 𝘪𝘯𝘴𝘪𝘨𝘩𝘵𝘴 👉 𝘛𝘢𝘨 𝘺𝘰𝘶𝘳 𝘪𝘯𝘯𝘰𝘷𝘢𝘵𝘪𝘷𝘦 𝘱𝘦𝘦𝘳𝘴 𝘵𝘰 𝘴𝘶𝘱𝘱𝘰𝘳𝘵 𝘵𝘩𝘦𝘪𝘳 𝘷𝘪𝘴𝘪𝘰𝘯 ---------------------------------------------------------------------- #CarloRivis #Innovation #VisionaryLeader #Startup #VentureCapital #Business #Leadership #ProblemSolver #Growth #𝐌𝐚𝐫𝐤𝐞𝐭𝐅𝐢𝐭
Astrobiome Space, SARL a republié ceci
Co-founder and CSO at Minutia.AI-Research and Gut Microbiota testing for Sports and Longevity -B2B
The #Brain-#Gut-#Muscle #Axis: a new frontier in exercise physiology? 💫 The concept of the brain–gut–muscle axis is gaining attention as a fundamental crossroad for energy homeostasis, exercise performance and overall health. As Marcus Aurelius said: "Reject your sense of injury, and the injury itself disappears”, the mind can be in control of the body, in health or disease, in healing or exercising. ✨ Communications between the gut microbiota and the nervous system (#gut– #brain #axis) involves the enteric nervous system, vagus nerve, the immune and endocrine systems. The enteric nervous system, made by enteroendocrine cells, release hormones that cross the blood brain barrier (BBB), reaching the brain cells. The vagus nerve, intricately connected to enteroendocrine cells, represents a central link in the gut-brain crosstalk. Immune-signaling mediators such as cytokines, chemokines, and microbial-associated molecular patterns (MAMPs) play a crucial role in the communication between the gut microbiota and the brain. Through these signaling pathways, the gut microbiota influences #immune #responses and #neuroinflammation, while the brain acts regulating motility, mucus secretion, barrier integrity, and visceral sensitivity. One example? Let’s focus on #lactate and its role as signalling molecule... 🚦 Far beyond being a waste or fatigue substance, lactate is a stress-related signaling molecule that plays key roles in health and disease. Biomarker, used in exercise and sport physiology, lactate positively correlates with exercise intensity (stress level). Some of its pleiotropic functions include: 1. regulation of energy production (Cori’s cycle, also extended to the gut with SCFA release, crossroad between glycolysis and oxidative metabolism, changes in substrate utilization); 2. cross-talking between tissues via monocarboxylate transporter isoforms (MCTs); 3. epigenetic role (lactylation) Lactate clearance, production, and transportation are not only regulated by exercise intensity, type of metabolism and glucose availability, but also by genetic variations in lactate-related genes (MCTs) and gut microbiota. #Veillonella #atypica (next generation probiotic developed by FitBiomics), #Eubacterium #hallii, #Anaerobutyricum #hallii, #Anaerostipes are examples of bacteria that metabolize lactate into SCFAs supporting energetic need in endurance and promoting SCFA delivery to the brain. While #exercise boosts the flux of SCFAs and lactate via an increased expression of MCTs, in neuropathological diseases, tissues are not efficiently clearing this metabolite, resulting in an allostatic overload and consequent symptoms. Regular and moderate exercise, reshaping gut microbiota diversity and metabolic activity, elicits positive impacts on muscle, brain and overall well-being. How far are we from gut microbiota-based, precision exercise interventions? ⌛ 🚴 📄 LINK: https://lnkd.in/dxhQZKqJ www.minutia.ai