Calculus Capital

“That’s what wakes me up in the morning [… seeking] a positive return on investment, and we get to make sure that people have longer, healthier, happier lifespans.” – We talk investing in life sciences, technology and media content with Elizabeth Klein of Calculus Capital. Watch now: ⏯ https://lnkd.in/eQ-VD6N4. In this interview:  ‣ Backing Laverock Therapeutics – novel gene silencing technology from a repeat entrepreneur David Venables, coinvesting with Lilly Ventures ‣ Investing in Tagomics – detection of origins of cancer, spun out from University of Birmingham, coinvesting with Illumina Ventures and Agilent Technologies ‣ How do past investments in Horizon Discovery and Synpromics Ltd help Calculus win deals? ‣ Maturing holdings Oxford BioTherapeutics and Tozaro ‣ Exits, including ActiveOps ‣ Risks, risk management, and current opportunities in venture capital   Watch the interview to learn more: ⏯ https://lnkd.in/eQ-VD6N4 Or listen later on:  🎧 Spotify https://lnkd.in/e4ErcV_V 🎧 Apple Podcasts https://lnkd.in/eQTvqQ9G   IMPORTANT The opinions expressed in this video are the interviewee’s own and do not necessarily reflect the view of Wealth Club Limited. This interview, like our service, is not advice. The investments described are high risk and illiquid. #lifesciences #venturecapital #investing

Scaling companies is a key engine of growth for the UK economy. techUK represents scale ups and helps inform and shape how the government approaches policy and regulation. It holds regular events advising scale ups and Calculus Investor Aitian Li, CICPA recently attended a joint event with VenturePath. She shared advice on how to secure scale up funding. If you missed the event and would like more information, please get in touch.

Hargreaves Lansdown has partnered with the Calculus Capital VCT to launch it's new VCT online investment service. Greater accessibility to VCTs benefits both UK entrepreneurs and investors looking to navigate a post budget tax landscape. Calculus Capital is excited to be 1 of 3 VCT managers participating in the launch. https://lnkd.in/e4UxsXg7

📢 Tagomics partners with Agilent Technologies to offer a novel solution for multiomic analysis!   We’re delighted to announce that we have entered into a strategic co-marketing agreement with Agilent Technologies, integrating the Agilent SureSelect™ Library Preparation and Target Enrichment system into our Interlace™ multiomics platform. This combined solution provides comprehensive genomic and epigenomic insights from a single sample in a unified workflow. Read the full press release 📰 and our latest application note 📄 where we demonstrate the potential of this combined approach on our website: https://lnkd.in/e29AkMbN 💻 Register for the early access programme: https://lnkd.in/e9esbG85   #Multiomics #Genomics #Epigenetics #Oncology #Diagnostics #Therapeutics

'Lee', the new biographical drama starring Kate Winslet and produced by the Calculus Capital production company Brouhaha Entertainment, has taken the top spot for Sky UK's box office record. Another great example of the premium content being produced by the creative portfolio companies held across the Calculus EIS and VCT. https://lnkd.in/ePdvB2rk

The Chancellor used the Autumn Statement as an opportunity to identify the critical role EIS and VCTs play in creating a positive environment for UK entrepreneurship. Read our budget review and what this means for tax efficient investing https://lnkd.in/ewjtCEH4

We're #hiring a new Sales Development Representative to join our Investor Relations team in London. Apply today or share this post with your network.

Webinar Alert: 'EIS investing to protect against tax hikes' - 10am on 13 November 2025 After the upcoming budget, we'll be putting on a Webinar discussing how Knowledge Intensive EIS Funds can be used to mitigate a number of tough decisions the chancellor has decided to make on personal taxes whether it be CGT, IHT or pension changes. If you'd like to be involved please sign up in the link below: https://lnkd.in/eR9ANrE9

We are excited to back insurtech company, Optalitix, in their latest fundraising round. We look forward to continuing our collaboration with their outstanding management team Dani Katz and Jonathan Shapiro. Funds will be used to further accelerate product innovation and execute their ambitious expansion plans.

"Teaming up with Calculus was a really big decision but has been nothing but a really great decision because we now have this very tight but very focussed and ambitious team." Jude Law on Riff Raff's investment from Calculus.