American Cancer Society Journals

The 2025 American Cancer Society Cancer Statistics report, published today in CA: A Cancer Journal for Clinicians, provides the latest insights into cancer incidence, mortality, and disparities in the United States. Key findings: 📌 A 34% decline in cancer mortality since 1991 has averted approximately 4.5 million deaths. 📌 Rising cancer incidence among women and younger adults is shifting the cancer burden. 📌 Stark disparities persist, with cancer mortality rates 2-3 times higher in some racial and ethnic groups. The authors emphasize the importance of sustained efforts in cancer prevention, research, and equitable access to care. Access the full report, available for free in CA: https://lnkd.in/e9hJbRyw Authored by Rebecca Siegel MPH, Tyler Kratzer MPH, Angela Giaquinto MSPH, Hyuna Sung PhD, and Ahmedin Jemal DVM, PhD OncoAlert William Dahut Arif Kamal MD, MBA Don S. Dizon Christina Annunziata Sumanta Pal, MD, FASCO

Just published in Cancer 📗 Can exercise help colon cancer survivors live as long as matched individuals in the general population? https://lnkd.in/eAm3jaUH Physical activity may help colon cancer survivors achieve long-term survival rates similar to those of people in the general population, according to a recent study led by Justin Brown, PhD, of the Pennington Biomedical Research Center and the Louisiana State University Health Sciences Center. “This new information can help patients with colon cancer understand how factors that they can control—their physical activity levels—can have a meaningful impact on their long-term prognosis,” said Dr. Brown. “Also, medical and public health personnel and policymakers are always seeking new ways to communicate the benefits of a healthy lifestyle. Quantifying how physical activity may enable a patient with colon cancer to have a survival experience that approximates their friends and family without cancer could be a simple but powerful piece of information that can be leveraged to help everyone understand the health benefits of physical activity.” Authored by Justin C. Brown PhD, chao ma MS, Qian Shi PhD, Leonard B. Saltz MD, Anthony Shields MD, and Jeffrey Meyerhardt MD, MPH OncoAlert #ColonCancer #ExerciseOncology #CancerResearch

A new report from American Cancer Society researchers shows cancer mortality rate declined from 1991 to 2022 by 49% and 33% in Black men and women in the US, but Black people have disproportionately elevated cancer burden compared to other population groups. Similarly, survival is lower in Black people than in White people for almost every type and stage of cancer, with the largest gaps for melanoma, uterine corpus, and cervical cancers. Read "Cancer statistics for African American and Black people, 2025" now available #OpenAccess in CA: A Cancer Journal for Clinicians: https://lnkd.in/eeeYh8ZD Authored by Anatu Saka MPH, Angela Giaquinto MSPH, Lauren McCullough PhD, Katherine Tossas PhD, MS, Jessica Star MPH, Ahmedin Jemal DVM, MPH, and Rebecca Siegel MPH OncoAlert

📢 CA: A Cancer Journal for Clinicians has published its first randomized clinical trial: a multicenter phase III study on reduced-volume vs. conventional radiotherapy after induction chemotherapy in nasopharyngeal carcinoma (NPC). 📖 Read the full #OpenAccess study: https://lnkd.in/ehmDZ792 Radiotherapy is the standard treatment for NPC, but guidelines have traditionally recommended targeting the pre-chemotherapy tumor volume, leading to unnecessary radiation exposure and severe side effects. This trial, led by Jun Ma, MD, from Sun Yat-sen University Cancer Center, found that targeting only the post-chemotherapy tumor volume maintained excellent locoregional control, reduced toxicity, and improved quality of life for patients. This research represents an important advancement in NPC treatment and a milestone for CA as we expand to include high-impact clinical trial research. As with all articles in CA, this study is free to read, ensuring that clinicians, researchers, and patients everywhere have access to the latest findings in oncology. 🔬 Watch Dr. Ma discuss the findings in the video below. OncoAlert #CancerResearch #Radiotherapy #NasopharyngealCancer #Oncology #ClinicalTrials

Working in Developmental Therapeutics and looking to share your novel findings with a global audience? 🌍 Cancer, an international interdisciplinary journal of the American Cancer Society, is calling for submissions to its new Developmental Therapeutics section led by Sandip Patel, M.D.. Dr. Patel is looking for high-quality manuscripts describing early-phase clinical trial results and research on novel mechanisms of therapy. Watch the video to learn more about the types of papers Dr. Patel is looking for. 📝 Ready to submit your work? Learn why Cancer should be the home for your next paper: https://lnkd.in/euKirYcY OncoAlert

📗 A new open access commentary in CANCER outlines how the patient navigator job roles table can be used to create job descriptions for entry, intermediate, and advanced levels of oncology patient navigation. This resource helps administrators develop standard-aligned roles and provides a clear path for navigators to advance in their careers. Unlike other frameworks that separate patient navigators, nurse navigators, and social work navigators, this resource applies to all patient navigators across levels of expertise. Read the full commentary here: https://lnkd.in/ebBqqgRJ Authored by Arti Patel Varanasi PhD, MPH, CPH, Linda Burhansstipanov DrPH, MSPH, OPN-CG, Sharon Gentry MSN, RN, Michelle C. MS, Carrie Dorn MPA, LMSW, Julie McMahon MPH, Kimberly Bradsher BS, Elba L. Saavedra Ferrer PhD, MS, OPN-CG, LaSonia Barnett MA, Margo Leighliter MHA, BSN, RN, OCN, Donna Moore Wilson MSN, RN, CBCN, and Tracie Lewis MS American Cancer Society National Navigation Roundtable #PatientNavigation #Oncology #CancerCare

New in Cancer 📗 Does pain affect cancer survivors’ use of non-opioid substances? https://lnkd.in/euHq5_PY Experiencing pain may increase the odds that cancer survivors will use cigarettes and cannabis according to this recent study. The study also found that cigarette smoking and pain are linked to more treatment-related side effects and worse health among cancer survivors.  Pain and use of cigarettes, e-cigarettes, alcohol, and cannabis commonly occur together in the general population. To characterize pain in relation to such non-opioid substance use specifically among cancer survivors (who often experience pain), investigators analyzed data from two national samples of individuals with a past diagnosis of cancer in the United States: 1,252 adults from Wave 6 (2021) of the Population Assessment of Tobacco and Health (PATH) Study and 4,130 adults from the 2020 National Health Interview Survey.  PATH data indicated that higher past-week pain intensity was associated with a greater likelihood that cancer survivors would use cigarettes, e-cigarettes, and cannabis, and a lower likelihood that they would drink alcohol. National Health Interview Survey data indicated that chronic pain was associated with a greater likelihood of cigarette smoking and a lower likelihood of alcohol use. In both studies, cigarette smoking and pain were linked to fatigue, sleep difficulties, poorer mental/physical health, and lower quality of life. “These findings show that because pain and substance use are interconnected among cancer survivors, it’s important to focus on treating both together in cancer care. Pain can drive substance use, and substance use can worsen pain, creating a cycle that’s hard to break,” said lead author Jessica Powers PhD, of Northwestern University - The Feinberg School of Medicine. “While cancer survivors might smoke cigarettes or use substances to get immediate relief from their pain and cope with other symptoms, this can be incredibly harmful for their health by reducing the effectiveness of cancer treatments and increasing risk for cancer recurrence.” Lisa LaRowe Dana Rubenstein Judy Paice Christine Rini OncoAlert

Just published in Cancer Cytopathology 📘 Pericardial fluid evaluation: Diagnostic yield and cytology–histology correlation https://lnkd.in/eTG6FZEQ Authored by Elie Tannous MD, Sana Malik BASc, and Syed M. Gilani MD Abstract Background Pericardial effusion can be due to any etiology but may cause significant morbidity and mortality; however, malignant effusions are rare, and accurate and timely diagnosis is essential for appropriate further management. Data on the actual comparison of pericardial cytology and surgical specimens are limited, and this study was conducted to evaluate an institutional cohort and compare these two samples. Methods The institutional electronic database system was retrospectively searched between January 2019 and December 2023 for pericardial biopsies/surgical specimens (PSSs) and cytology. Results A total of 202 surgical specimens of the pericardium were identified from patients with a median age of 67 years and a range of 18–97 years. Of these 202 cases, 190 specimens also underwent cytological evaluation, which included 153 cases that were negative for malignancy, nine cases that were indeterminate/atypical, and 28 cases that were positive for malignancy. Agreement between cytology and PSSs was reached in 172 cases, with 153 being benign and 19 being malignant. However, a cytology–histology discrepancy was found in 18 cases. Of these 18 cases, nine showed positive cytology but all had negative concurrent PSSs except for one with focal atypia, and the remaining nine were indeterminate/atypical on cytology. Eight of these nine indeterminate cases were negative on the PSS, whereas one atypical cytology case with low cellularity showed a positive PSS. Conclusions If atypical cases are excluded, cytology demonstrates a better diagnostic yield for detecting malignancy compared to surgical specimens (n = 28 cases vs. n = 20 cases, respectively). #CytoPath

We are pleased to welcome Jennifer Knight, MD, MS as the new Psychosocial Oncology Section Editor for the journal Cancer! 📗 Dr. Knight is a professor of psychiatry and behavioral medicine at the Medical College of Wisconsin whose research focuses on the physiologic and immunologic mechanisms underlying the relationship between psychosocial factors and clinical outcomes in patients with cancer, particularly among transplantation and cellular therapy recipients. Please join us in welcoming Dr. Knight!👏

ICYMI: The American Cancer Society is launching an open access journal focusing on pediatric, adolescent, and young adult (AYA) oncology. We’re seeking a founding Editor-in-Chief to establish its mission, build the editorial board, and shape its vision for years to come. Learn more about this exciting opportunity to shape the future of pediatric oncology publishing! Apply by February 15, 2025: https://lnkd.in/e4dbUtxp