Cancer Cell by Cell Press

Online Now: Global alliances in translational cancer research http://dlvr.it/TJJ8yD

Online Now: Metabolic engineering to facilitate anti-tumor immunity http://dlvr.it/TJH9Xs

Online Now: Probing cancer with small-molecule tools—Progress and challenges http://dlvr.it/TJGPVK

Online Now: FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma http://dlvr.it/TJFQ3d

Online Now: Nivolumab combined with induction chemotherapy and radiotherapy in nasopharyngeal carcinoma: A multicenter phase 2 PLATINUM trial http://dlvr.it/TJDHkQ

⌛ There are just three days until the #INCI25 abstract deadline! Make sure to submit your #cancerbiology or #inflammation research by this Friday, 28 February. You can present your research on stage during a selected talk or during the poster sessions and win the Cell Press Poster Prize🏆. To do so, upload it to https://lnkd.in/gV9hqbCG. You could be sharing the stage with one of these research leaders: Tal Arnon, Gabriele Bergers, Adrienne Boire, Chrysothemis Brown, Coco Chu, Michele De Palma, Wolf Hervé Fridman, Peter Friedl, Abhishek D. Garg, Nicolas Gaudenzio, Martin Guilliams, Brian S. Kim, Guido KROEMER, Bart Lambrecht, Ken Lau, Burkhard Ludewig, Laura Mackay, Miriam Merad, MD, PhD, Peng Min, Christoph Scheiermann, Georg Schett, Andrea Schietinger, Ton Schumacher, Shannon Turley, Sophie Ugolini, Pablo VARGAS, Gabriel Victora, Tobias Weiss, Cornelia Weyand, Laurence Zitvogel

Online Now: EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models http://dlvr.it/TJ6Lcc

Online Now: Integrative spatial analysis reveals tumor heterogeneity and immune colony niche related to clinical outcomes in small cell lung cancer http://dlvr.it/TJ5GKJ

Our February issue is online! https://lnkd.in/evBAyHaU   Read about Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity - an Article from Petya Apostolova (University of Basel), Robert Zeiser (Albert-Ludwigs-Universität Freiburg im Breisgau), & colleagues  https://lnkd.in/e8g2YnaW Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancer - an Article from Shichun Lu, Lei Zhang (Peking University Shenzhen Graduate School), Chen Dong (Westlake University), & colleagues https://lnkd.in/eYusBMnh Classification of non-TCGA cancer samples to TCGA molecular subtypes using compact feature sets - an Article from Kyle Ellrott (Oregon Health & Science University), Andrew Cherniack (Broad Institute of MIT and Harvard), Peter W. Laird (Van Andel Institute) & colleagues https://lnkd.in/eDMRX9yU Squamous cell cancers of the aero-upper digestive tract: A unified perspective on biology, genetics, and therapy - a Review from Anil K. Rustgi (Columbia University Irving Medical Center) & colleagues https://lnkd.in/eQTky6mN And more! On the cover: Francesca D. Ciccarelli & colleagues identify properties of the local tumor immune microenvironment that facilitate the response to immunotherapy in patients with colorectal cancer. The cover image is adapted from “Several Circles” (Einige Kreise, 1926), a painting by Wassily Kandinsky, with the central circular shape representing a cancer cell interacting with macrophages, NK cells, and T cells. Image credit: Joe Brock, Research Illustration Manager, The Francis Crick Institute https://lnkd.in/ew7h-H63

Online Now: Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases http://dlvr.it/THsQqt