MPS_NOVA Twinning

📢 Training workshop: Call for Registrations! 📢 The #MPS_NOVA Training Workshop on Strategy in R&I Management is now open for application! 🗓 Date: May 16, 2025 📍 Location: ITQB NOVA, Oeiras 👥 Vacancies: 25 📌 Deadline for application: April 16, 2025 Led by Dr. Seda Çöl Arslan, Head of the Research Funding Department at Max Delbrück Center, Berlin (MDC), and Dr. Nevine Shalaby, Head of Innovation and Enterpreneurship at Max Delbrück Center, Berlin (MDC), this one-day workshop will provide valuable insights into the role of Research & Innovation Managers. Topics will cover: ✅ Navigating the interface between science & administration ✅ Strategy development ✅ Committee support, Reporting, and appointments This training is open to Research Managers across the Greater Lisbon area! 🔗 Apply here with a short motivation letter and your CV: https://lnkd.in/dvmNwhC9 Don't miss this opportunity—secure your spot now! 🎯 #ResearchManagement #TrainingWorkshop #Lisbon #EuTwinning

We are pleased to invite you to an insightful #LS4FUTURE Online Informative Session on: "The Science Management Professions in Europe – Who Are These Professionals and What Tools Are There for Their Professional Development?" 📅 Date & Time: February 27th, 2 PM 📍 Online via Zoom Presented by Margarida Trindade, Head of ITQB NOVA Science Funding Office, this session will highlight key findings from the RM ROADMAP and #CARDEA projects, as well as insights from the European Commission’s Research Management Initiative (ERA Action 17). 🔍 The talk will cover: ✅ A comprehensive overview of research management professions in Europe, based on an extensive survey. ✅ Mapping of existing training programs in the field. ✅ Newly developed tools, including: • A European Competency Framework for Research Managers • A Training Catalogue for career development in research management 📢 This session (held in Portuguese) is particularly valuable for science managers, researchers, and institutional leaders within LS4FUTURE, providing key insights into the evolving landscape of research management. 📌 Join us and be part of the discussion! More info here 👉 https://lnkd.in/dNbeQSFe #ScienceManagement #ResearchManagement #CareerDevelopment #ERAAction17

👋 Do you have a research project in #HealthSciences? If the answer is 'yes' and you are aged 35 or under, this post is for you. 👇 The #MariadeSousaAward has distinguished and awarded five young Portuguese researchers every year since 2021, seeking to foster their research projects with financial support of up to 30,000 Euros each, including a mandatory internship at an international centre of excellence. 🤔 Sound interesting? Watch the video by Joana Gaifem, a post-doctoral researcher at the i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, and one of the winners of the Maria de Sousa Award 4th edition - 2024, and learn some helpful tips for future candidates. Applications for the Maria de Sousa Award 5th edition – 2025 are open until May 31. Learn more at 🌐 bit.ly/BFMariadeSousaAward 🤝 An exclusive partnership between Ordem dos Médicos and the #BIALFoundation #OrdemdosMédicos #FundaçãoBIAL #MariadeSousa #PrémioMariadeSousa

In this blog post, Dynamic42 GmbH showcases their organ-on-chip models for infectious disease research & discusses how these models are instrumental for unraveling infection mechanisms & developing new therapies. https://lnkd.in/eM9ZFPui 🔹 Antonia Last, Bernhard Hube and team at Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute established a 3D in vitro gut model to explore interactions between pathogenic fungus and the intestinal microenvironment. https://lnkd.in/eJzmjxn8 🔹 Stefanie Deinhardt-Emmer, Knut Rennert, Alexander Mosig, and team at Universitätsklinikum Jena and Center for Sepsis Control & Care (CSCC) created an alveolus-on-chip model with complete vacuolar and epithelial cell structures co-cultured with macrophages to study pneumonia. https://lnkd.in/eWUaXuik 🔹 Zoltan Cseresnyes, Marc Thilo Figge, and team employed an invasive aspergillosis-on-chip model to gain insight into fungal invasion of the lung, with the goal of identifying infection targets and testing antifungal drugs at clinically relevant concentrations. https://lnkd.in/eRNkZkuT 🔹 In this paper, researchers used a human liver-on-chip model to investigate how pathogens invade and persist in the liver. https://lnkd.in/eAMAPqvS 

✨ We are thrilled to announce the major results from our partnership with Dynamic42 GmbH, Bayer, and Placenta Lab of Jena University Hospital in pioneering research on drug safety during pregnancy! ✨ This collaboration represents a significant step forward in understanding how medications interact with maternal and fetal physiology – without relying on animal models.   Pregnant women often face uncertainty when it comes to medication safety, as traditional testing methods, such as animal models or simpler cell-based assays, have significant limitations. Many drugs lack comprehensive safety data for use during pregnancy, increasing the risk of unforeseen complications. Through this partnership, we developed an innovative three-organ microphysiological system (MPS) replicating the gut, liver, and placenta on biochips. By integrating this system with MPSlabs' digital twin technology, we can simulate drug absorption, metabolism, and placental transfer in pregnant women and, most importantly, the fetus with unprecedented accuracy. The combination of these technologies enables a deeper understanding of pharmacokinetics and enhances drug safety assessments for pregnant women.   The recent case study using Prednisone as a model drug demonstrated key findings: 🔷 Efficient Metabolism: The system accurately converted Prednisone into Prednisolone, reflecting human hepatic metabolism. 🔷 Limited Placental Transfer: The placenta-on-chip model effectively mimicked the barrier function, matching clinical observations. 🔷 Predictive Capability: The digital twin simulations aligned closely with experimental and clinical data, showcasing the reliability of our approach.   We are excited to continue this collaboration and push the boundaries of innovation in pregnancy-related drug safety.   👉 Read Dynamic42's blog post for an in-depth look at this great work! https://lnkd.in/eBTdx68z

“𝗠𝘂𝗹𝘁𝗶 𝗢𝗿𝗴𝗮𝗻 𝗠𝗼𝗱𝗲𝗹” - 𝗔𝗻𝗶𝗺𝗮𝗹-𝗳𝗿𝗲𝗲 𝗮𝗹𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝘃𝗲 𝗳𝗼𝗿 𝗽𝗵𝗮𝗿𝗺𝗮𝗰𝗼𝗸𝗶𝗻𝗲𝘁𝗶𝗰𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵: Organ-on-chip specialist Dynamic42 and ESQlabs, experts in digital life sciences solutions, have successfully developed a three-organ system, in close collaboration with  Consumer Health Division of Bayer, and the Placenta Lab at Jena University Hospital. The platform has the potential to significantly reduce animal testing using Organ-on-chip (OoC) technology and interactive computational software. The aim of the one-year pilot project was to collect clinically relevant data, crucial for the evaluation of new drug candidates in preclinical research. The results of the project have now been published in Frontiers in Pharmacology journal. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/ep_ty4yE Universitätsklinikum Jena, Martin Raasch, Dynamic42 GmbH, ESQlabs GmbH, Bayer, Christian Maass, Diana Morales Prieto, Ramy Ammar, Dr. Juliane Fischer