Orange County Bio

Advanced cellular immune therapeutics are reshaping treatment landscapes for cancer, autoimmune disorders, and other immune-related diseases. Yet, challenges in efficacy, access, safety, and manufacturing remain. This article highlights Ireland’s efforts to drive innovation in personalized cellular therapies by optimizing metabolism during biomanufacturing to control cellular heterogeneity and establishing an All-Ireland Research Center that integrates academic, clinical, regulatory, and manufacturing expertise to build a sustainable ecosystem for cellular therapeutics. Could this model help shape the future of global CGT innovation? Read more here: https://lnkd.in/gajbBYNb #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

🔬 NIH Budget Cuts: A Setback for U.S. Science 📉 The NIH’s recent funding cuts—reducing research support by $4 billion—have sparked widespread concern across the scientific community. With the NIH funding 60,000 grants last year alone, these cuts could slow innovation, disrupt research operations, and impact the future of biomedical breakthroughs. While the immediate effects may be felt in academic labs, the ripple effects could extend to biotech startups and novel therapeutics, including cell and gene therapies, which often originate from academic research. What could this mean for the future of scientific progress? Read more here: https://lnkd.in/gBdgZaR4 #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

💊 U.S. Drug Prices: The Upward Trend Continues 📈 Despite ongoing efforts to control U.S. drug costs, the latest TD Cowen report suggests that prices will continue their upward trajectory. Among the biggest drivers? Cancer drugs, cell and gene therapies, and treatments for diabetes, obesity, and rare diseases. With high-value, innovative therapies entering the market, spending is expected to keep climbing. In 2024 alone, per-unit branded drug costs increased 7% on average, up from 5% in 2023. What does this mean for the future of CGT affordability, access, and adoption? Read more here: https://lnkd.in/gGbg29YG #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

🚀 Want to Stand Out at Your Next Tradeshow? 🚀 Tradeshows are more than just booths and business cards—they're a chance to showcase your expertise, build real connections, and drive meaningful results. But success doesn’t happen by chance! This blog post breaks down key strategies to help you prepare like a pro, make an impact on the show floor, and follow up effectively to turn conversations into opportunities. Ready to maximize your next event? Check it out here: https://lnkd.in/g5NV44Pw #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing, #tradeshow

CAR-T and other cell therapies have transformed treatment for hematologic cancers, but major challenges remain in making them widely accessible. Complex manufacturing, high costs, and scalability issues limit expansion—especially into areas like autoimmune diseases. This article explores these hurdles and the financial pressures shaping the field. What will it take to bring these life-changing therapies to more patients? Read more here: https://lnkd.in/gpmuH7bG #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

Gene therapy development, especially AAV purification, requires careful planning and a strong process design to ensure success. In this expert roundtable, four industry leaders discuss key considerations, from Quality by Design (QbD) approaches to process intensification. They explore how to build flexible purification platforms that can adapt to different AAV serotypes while ensuring efficiency and regulatory compliance. A must-read for anyone in gene therapy development looking to optimize their purification processes! 👇 https://lnkd.in/g-Vj7TaT #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

🚨 Case Study Spotlight 🚨 If you are navigating the complexities of marketing in Cell & Gene Therapy, this case study is a must-read. It highlights how partnering with Orange County Bio can help reduce costs, minimize risks, and create more time for innovative breakthroughs. Check out the key takeaways, including the benefits of outsourcing, leveraging CGT-specific expertise, and optimizing efficiency. It’s a great example of how strategic partnerships can drive smarter, more impactful outcomes. Download the case study here: https://lnkd.in/gnhnUirQ #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

📢 The FDA’s recent draft guidance on Potency Assurance for Cellular and Gene Therapy Products is a game-changer, but interpreting and applying it isn’t without its challenges. In this insightful article, the authors explore how to navigate the new framework and ensure therapies consistently achieve their intended biological effects. Using a novel gene-modified cell therapy as a case study, we explore key principles and offer practical insights for real-world implementation. If you are involved in cell and gene therapy, this is a must-read! 👇 https://lnkd.in/gSvQ_9X9 #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing

We’re thrilled to announce that Orange County Bio will be joining the incredible lineup of startups at Advanced Therapies London this March! 🙌 It's a fantastic opportunity to connect with industry leaders, innovators, and fellow pioneers in the advanced therapies space. We can't wait to showcase what we’ve been working on and learn from all the amazing minds in attendance. If you’re attending the event, we’d love to connect! Feel free to reach out — let’s set up a time to chat and explore potential collaborations. See you there! ✨ #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing, #Leadership, #adtherapies25

The energy at ATW 2025 was phenomenal! We had amazing and fruitful discussions with so many colleagues, and we’re excited to continue the conversation and explore new opportunities in the Cell and Gene Therapy space. If we didn’t get a chance to connect during the event, don’t hesitate to reach out—we’d love to keep the dialogue going! 💬 Let us know your key takeaways from the event! #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #GeneTherapy, #Consulting, #Marketing, #Leadership, #ATW2025