Scale Biosciences

🔬 A Quantum leap for single cell! Learn more in our blog about the technology powering our 100 Million Cell Challenge: Quantum Barcoding Key innovations: ✨ Novel microwell-within-well architecture eliminating complex split-pool steps ✨ Process up to 2 million cells in just 1.5 days ✨ 75% reduction in hands-on time ✨ Cost-effective at just $0.01 per cell ✨ Supports up to 9,216 samples per run Unlike traditional chip-based approaches, our platform isn't constrained by channel configurations or microfluidics, enabling seamless expansion into multiple modalities including protein profiling. Ready to transform your single cell research? QuantumScale Single Cell RNA-seq is available now through our Service Lab, or inquire about early access. #SingleCell #Genomics #Biotechnology #Innovation #Research #LabTechnology Read our blog article for more: https://hubs.la/Q02Z4SR_0

🧬 Breaking barriers in functional genomics! New data showcases high-throughput CRISPR screening at single-cell resolution. See how we profiled 135K cells and 192 guides to decode the TNFα pathway with remarkable precision. Scale Bio's latest application note reveals a powerful workflow for next-gen CRISPR screens. Get the full technical details: https://hubs.la/Q02Z02gd0 #SingleCell #CRISPR #Genomics

📢 Join our webinar to explore how single cell omics technologies are transforming xenotransplantation research! 🔬In this webinar, featuring Dr. Brendan Keating from NYU Langone Health, you will learn: •Why xenograft research is imperative to address the organ shortage crisis •How single cell technologies are enabling deep profiling of blood and tissue in an unbiased fashion •How omics approaches, such as single cell methylation, can be used to generate diagnostic and prognostic markers of xenograft damage 📅 Date: Wednesday, December 11 ⏰ Time: 10:00 AM PT/ 1:00 PM ET 🔗 Register here: https://hubs.la/Q02Z3Blf0 #Xenotransplantation #Biotechnology #MedicalResearch #genomics #Innovation #singlecell #methylation

🔬 Drug Discovery: Profile 384 conditions simultaneously with single cell precision Scale Bio's ScalePlex technology just transformed high-throughput drug screening. Our latest application note demonstrates: • ScalePlex and the Scale Bio Single Cell RNA Sequencing Kit v1.1 enabled high-throughput profiling of 384 conditions simultaneously in 1.5 days. • We tested 40 FDA-approved targeted therapies across 4 timepoints on K562 cells, demonstrating high cell recovery and sensitivity. • Unbiased clustering revealed drugs with similar transcriptional responses, while temporal analysis showed dynamic changes in gene expression associated with drug responses. • We validated known BCR-ABL inhibitors and identified potential novel therapeutic targets, showcasing its utility in drug discovery. Ready to revolutionize your drug discovery pipeline? Download our application note. https://hubs.la/Q02YJvlQ0 #DrugDiscovery #Biotechnology #SingleCell #Research

Excited to announce a groundbreaking collaboration between Scale Biosciences and Revvity's BioLegend! 🎉 We've just launched the TotalSeq™ Phenocyte™ solution - a first-of-its-kind approach for high parameter protein profiling at the single cell level. This innovative solution combines Scale Bio's Quantum Barcoding technology with BioLegend's trusted TotalSeq™ antibodies to help researchers: ✨ Identify and characterize rare cell subtypes 🧬 Scale up immunology and oncology research 📊 Analyze more markers in a single experiment 🔬 Simplify complex workflows 💡 Access high-parameter protein analysis without dedicated instrumentation Ready to transform your single-cell research? The TotalSeq Phenocyte solution is shipping now! https://hubs.la/Q02YJfHZ0 #SingleCell #Biotechnology #Research #Innovation #CellBiology #Immunology #Oncology

📢 Reminder! Happening today at 10:00 AM PT/1:00 PM ET Webinar: Unlocking New Therapeutic Targets in Pediatric Brain Tumors Through Single-Cell Analysis Join us to explore David Rincón Fernandez Pacheco's groundbreaking research using cutting-edge #singlecell multi-omics to reveal specific therapeutic targets in pediatric gliomas. Learn about how he uncovered distinct molecular signatures that could revolutionize personalized treatment approaches for these devastating childhood cancers. Key insights you'll gain: •Latest advances in single cell multi-omic strategies for tumor analysis •Novel therapeutic targets revealed through integrated methylation/RNA analysis •Practical applications of Scale Bio's solutions for complex disease research This is essential knowledge for oncologists, researchers, and anyone interested in advancing pediatric cancer treatment. Register here: https://hubs.la/Q02Y4-GD0

📰 Good news travels fast! Thanks to Genetic Engineering & Biotechnology News for highlighting our #100MCellChallenge winners announcement! Check out the article to learn more about this ground-breaking initiative from Scale Biosciences! https://hubs.ly/Q02XTB8v0 🌟 #singlecell #innovation #genomics

We had such a blast hosting our #ASHG2024 happy hour event at STK Steakhouse Denver! It was the perfect mix of our valued customers, partners, colleagues, and vibes! Our guests enjoyed our speciality cocktail, the #singlecell sizzle, and discussed their current and potential future projects with us. Thanks to everyone for joining!

🧬 Exciting news! Scale Bio's 100M Cell Challenge draws unprecedented response with nearly 1 BILLION cells in proposed research projects across 27 countries! We're thrilled to announce the winning projects that will tackle critical challenges in global health - from childhood respiratory diseases to cancer disparities. Due to the overwhelming response and quality of submissions, we're expanding support to all qualifying projects. This initiative, backed by Chan Zuckerberg Initiative, Ultima Genomics, NVIDIA, and BioTuring, demonstrates the massive demand for accessible, large-scale single cell analysis. At just 1¢ per cell, our QuantumScale and ScalePlex technologies are removing barriers to help researchers analyze millions of cells instead of thousands. Key focus areas: - Global Health Equity - Disease Characterization - Cancer Biology - Therapeutic Innovation Learn more about the winning projects: https://hubs.la/Q02Xhkbh0 #Genomics #biotechnology #research #science #innovation #globalhealth

Join us today at booth 785 at the #ASHG24 meeting! We unveil some of the winners from our #100MillionCellChallenge in this afternoon's CoLab session, and show you how we're making massive-scale single cell projects more accessible and affordable than ever. Learn More: https://hubs.la/Q02X5WBZ0 #singlecell #genomics