Age Breaker’s Post

𝐀𝐫𝐞 𝐓𝐨𝐦𝐚𝐭𝐨𝐞𝐬 𝐚 𝐒𝐮𝐩𝐞𝐫𝐅𝐨𝐨𝐝? 🍅 🍅 Lycopene is a carotenoid and is related to beta-carotene, which gives vegetables and fruits a red 🍅colour, it is a powerful antioxidant that is associated with tomatoes 🍅, but it is also found in watermelons🍉, grapefruits, apricots etc. Lycopene has been associated with powerful anti-ailment properties and is used as a supplement for high blood pressure, high cholesterol and to reduce inflammation 🔥. Mainstream science is yet to be fully convinced, however. Muhdo Health analyses 1000s of data points from supplements, genotypes 🧬, cg site methylation, diet 🥗, exercise 🏃♂️etc. Going through the data we have discovered a link between lycopene intake and increased methylation (lower expression) on the gene IL-6 🔥. Increased expression of IL-6, especially chronic expression is associated with heart ❤️disease, cancer, T2D, IBS and autoimmune conditions. Those who have been taking lycopene (30-50mg per day) as a separate supplement for more than 6 months showed higher methylation on a specific cg site located on IL-6 which may infer lowered expression and therefore decreased inflammation. ❄️ High dietary intake of tomatoes 🍅, puree and paste will most likely illicit similar results as the dosages from high dietary intake will mimic supplementation and provide other valuable nutrients such as vitamin C and fibre. The moral of the story is to eat a balanced diet but perhaps balance it a little bit more towards increased lycopene intake.🍅🍅 #health #food #science #data #lycopene #superfoods #epigenetics #muhdo #inflammation #tomatoes #methylation #genetics

𝐀𝐫𝐞 𝐓𝐨𝐦𝐚𝐭𝐨𝐞𝐬 𝐚 𝐒𝐮𝐩𝐞𝐫𝐅𝐨𝐨𝐝? 🍅 🍅 Lycopene is a carotenoid and is related to beta-carotene, which gives vegetables and fruits a red 🍅colour, it is a powerful antioxidant that is associated with tomatoes 🍅, but it is also found in watermelons🍉, grapefruits, apricots etc. Lycopene has been associated with powerful anti-ailment properties and is used as a supplement for high blood pressure, high cholesterol and to reduce inflammation 🔥. Mainstream science is yet to be fully convinced, however. Muhdo Health analyses 1000s of data points from supplements, genotypes 🧬, cg site methylation, diet 🥗, exercise 🏃♂️etc. Going through the data we have discovered a link between lycopene intake and increased methylation (lower expression) on the gene IL-6 🔥. Increased expression of IL-6, especially chronic expression is associated with heart ❤️disease, cancer, T2D, IBS and autoimmune conditions. Those who have been taking lycopene (30-50mg per day) as a separate supplement for more than 6 months showed higher methylation on a specific cg site located on IL-6 which may infer lowered expression and therefore decreased inflammation. ❄️ High dietary intake of tomatoes 🍅, puree and paste will most likely illicit similar results as the dosages from high dietary intake will mimic supplementation and provide other valuable nutrients such as vitamin C and fibre. The moral of the story is to eat a balanced diet but perhaps balance it a little bit more towards increased lycopene intake.🍅🍅 #health #food #science #data #lycopene #superfoods #epigenetics #muhdo #inflammation #tomatoes #methylation #genetics

Inulin is a dietary fiber found in plants like for example Jerusalem artichoke, chicory, artichoke, asparagus, leek, or onion. Dietary fiber is satiating so they play an important role in a healthy way of weight loss. But inulin is more than just a weight loss aid, it has many positive effects on human health. Inulin is not absorbed or digested in the small intestine. In the large intestine, the inulin is then fermented by bifidobacteria. Bifidobacteria can inhibit the growth of harmful bacteria, are involved in stimulating the immune system and in the synthesis of B vitamins. Bifidobacteria produce acetate and lactate, which lowers the pH value, which in turn can reduce the growth of pathogens. The lower pH value has also a positive impact on the bioavailability of calcium, iron and magnesium. The end product of the fermentation are so called SCFA`s (short chained fatty acids). SCFA`s increase mucosal blood flow and mucosal cell proliferation. Moreover they are necessary for the microbiome to keep the production of redox equivalents in the intestine in balance. They also serve as an energy source for colonocytes (cells in the intestine). As a result, short-chain fatty acids improve the integrity of the intestinal barrier, glucose and lipid metabolism; they regulate the immune system, inflammatory reactions and blood pressure. Another advantage of inulin is that its metabolism is independent of the insulin hormone, the blood sugar level remains relatively unaffected, which is why Jerusalem artichokes are also suitable for diabetics. But even if that all sounds great, you shouldn't exaggerate by consuming inulin-containing foods. Consuming small amounts regularly is better than a lot at once. As a daily intake you should not consume more than 40 g of inulin. If you want more info about this topic – here are our sources: https://lnkd.in/dDvr4A5N https://lnkd.in/d4-8Jd9g https://lnkd.in/dP-UMpVj https://lnkd.in/dJbe79Ah https://lnkd.in/dmhnTsxg

How do nutraceuticals help in preventing chronic diseases? Nutraceuticals play a significant role in the prevention of chronic diseases by providing essential nutrients and bioactive compounds that support overall health and mitigate disease risk. Chronic diseases, such as heart disease, diabetes, and cancer, are often linked to poor nutrition and lifestyle choices. Nutraceuticals can help address these issues by supplying antioxidants, vitamins, minerals, and other beneficial compounds that promote physiological functions and protect against oxidative stress. For example, omega-3 fatty acids found in fish oil are known to reduce inflammation and lower the risk of cardiovascular diseases, while dietary fiber can help manage blood sugar levels in individuals with diabetes. Specific nutraceuticals have been identified for their preventive effects against various chronic conditions. Curcumin, a compound in turmeric, exhibits anti-inflammatory properties that can alleviate symptoms of arthritis and may reduce cancer risk. Similarly, vitamins such as D and E, along with minerals like magnesium and selenium, contribute to immune function and overall health maintenance. Additionally, probiotics found in fermented foods enhance gut health and boost immunity, further aiding in disease prevention. By integrating these nutraceuticals into daily diets, individuals can potentially lower their risk of developing chronic diseases and improve their overall well-being. hashtag #extracts hashtag #nutraceuticals hashtag #healthsupplements hashtag #dietarysupplements hashtag #prakruti

It’s fascinating how plants can have biochemical molecules that closely resemble those in humans but have a unique structure to suite their own purpose. Such is the case with phytosterols. This molecule is structurally like the cholesterol found in humans and serves many similar purposes. In plants, phytosterols are a component of cell membranes, a precursor to hormones, and a part of the stress response, and the same things can be said of cholesterol in humans. The similar chemistry of phytosterols and cholesterol gives the former some potent health benefits in humans. Phytosterols compete with cholesterol for absorption in the human small intestine. Consuming phytosterols can lower the amount of cholesterol absorbed and result in lower blood levels of cholesterol, a desirable outcome since high blood cholesterol has been associated with an increased risk for cardiovascular disease. A recent study highlights these phytosterol benefits. Researchers conducted a 12-week cross-over study on 23 men who were instructed to follow a healthy diet and supplement with 2.6 grams of phytosterols every day. The protocol reduced total cholesterol, increased high density (healthy) cholesterol, and reduced intermediate-density lipoprotein levels. Looking to get more plant sterols in your diet? Seeds and oils such as rapeseed, flaxseed, and olive are rich in phytosterols. Nuts, whole grains, and legumes also contain good amounts of these compounds. 

Aging and glycation, what's new? Alcoholic beverages and glycation: triple punishment. Already responsible for over 200 diseases, alcohol is a booster of glycation and therefore of accelerated aging! Obtained by fermenting plant sugars, then sometimes by distillation, alcoholic beverages are often very high in calories. Worst of all, some alcohol-based cocktails enriched with sugary drinks. Conversely, depending on the grape variety, some red wines contain very few calories. For many consumers, alcohol is the main source of excessive sugar consumption, leading via glycation to accelerated aging and age-related diseases.   Numerous studies show that addictive alcohol consumption is a major factor in the etiology of cognitive decline and dementia. A recent study shows that the mechanisms by which alcohol affects cognitive functions are linked to glycation via the activation of AGEs receptors, making alcohol an over-accelerator of glycation and therefore of aging (1).   Alcohol alone is responsible for over 200 diseases! What's more, many alcoholic beverages, with their high sugar content, fuel glycation and thus aging. Finally, alcohol accelerates glycation, making alcohol consumption a bomb toward accelerated aging and age-related diseases. © AGE Breaker 04 2024 [Glycation is one of the major causes of aging. Resulting from the fixation of sugars on the proteins constituting the organism, glycation generates toxic compounds that cause cellular aging. Glycation is particularly involved in metabolic disorders, skin aging and cognitive decline.] [AGE BREAKER, patented nutritional supplements, based on rosmarinic acid, recognized by aging specialists around the world for their properties to reverse the effects of glycation.] More on https://swll.to/3Qtq8i #agebreaker #glycation #antiaging #longevitymedicine #preventivemedicine #preventivehealth #skinaging #4pmedicine #advancedglycationendproducts (1) : RODRÍGUEZ DE FONSECA, Fernando, MEDINA-PAZ, Francisco, SAPOZHNIKOV, Mira, et al. Plasma Concentrations of High Mobility Group Box 1 Proteins and Soluble Receptors for Advanced Glycation End-Products Are Relevant Biomarkers of Cognitive Impairment in Alcohol Use Disorder: A Pilot Study. Toxics, 2024, vol. 12, no 3, p. 190. https://swll.to/f3C4V

Research Trends：Long-term Supplementation of DHA Can Help Protect Mental Health 💗 Did you know that DHA (docosahexaenoic acid), an Omega-3 fatty acid sourced from microalgae, plays a crucial role in protecting Mental Health? DHA is one of the main structural components of the brain. International research shows that DHA helps improve the delivery of the happy substance "serotonin" in the brain. Effectively relieves stress and reduces the chance of depression or other mental problems. Meanwhile, it has functions such as promoting intelligence, memory and concentration, allowing people to work longer and work more efficiently. ◉Long-term supplementation of Omega-3 (especially DHA) can help reduce the risk of Alzheimer's disease. A research report7 published in the "American Journal of Clinical Nutrition" in June this year followed 1,135 participants without AD to evaluate the relationship between omega-3 fatty acid supplementation and the onset of AD over a 6-year period. The results showed that long-term use of omega-3 fatty acid supplements reduced the risk of AD by 64%. The study then analyzed 48 published studies involving 103,651 participants. The conclusion was that a 0.1 gram per day increase in DHA or EPA intake reduced the risk of cognitive decline by approximately 9%. Long-term supplementation with omega-3s, especially DHA, may reduce the risk of AD or cognitive decline. ◉Benefits of Microalgae Unlike fish-derived Omega-3s, microalgae has a higher naturally occurring DHA content, is safer and more sustainable, and has a more acceptable smell. Research has found that marine microalgae are the original producers of polyunsaturated fatty acids such as DHA. They are passed through the food chain and stored in fish and seafood. Today, Runke Biotechnology has reached the world's leading level in terms of production scale and product stability of microalgae DHA. DHA derived from microalgae has a pure taste, no fishy odor, and almost no EPA. It has the characteristics of safe quality, controllable quality, traceability, and recyclability. It is very suitable for consumption by infants, young children, pregnant women, etc. Let's protect your mental health,naturally. 🙆♀️ #MentalHealth #DHA #Omega3 #Nutrition #Microalgae #Sustainability #Runke

How do nutraceuticals help in preventing chronic diseases?  Nutraceuticals play a significant role in the prevention of chronic diseases by providing essential nutrients and bioactive compounds that support overall health and mitigate disease risk. Chronic diseases, such as heart disease, diabetes, and cancer, are often linked to poor nutrition and lifestyle choices. Nutraceuticals can help address these issues by supplying antioxidants, vitamins, minerals, and other beneficial compounds that promote physiological functions and protect against oxidative stress. For example, omega-3 fatty acids found in fish oil are known to reduce inflammation and lower the risk of cardiovascular diseases, while dietary fiber can help manage blood sugar levels in individuals with diabetes. Specific nutraceuticals have been identified for their preventive effects against various chronic conditions. Curcumin, a compound in turmeric, exhibits anti-inflammatory properties that can alleviate symptoms of arthritis and may reduce cancer risk. Similarly, vitamins such as D and E, along with minerals like magnesium and selenium, contribute to immune function and overall health maintenance. Additionally, probiotics found in fermented foods enhance gut health and boost immunity, further aiding in disease prevention. By integrating these nutraceuticals into daily diets, individuals can potentially lower their risk of developing chronic diseases and improve their overall well-being. #extracts #nutraceuticals #healthsupplements #dietarysupplements #prakruti

Exploring Nutritional Interventions in Sport-Related Concussion Management Concussions in sports, a significant concern affecting countless athletes annually lead to a complex neurometabolic cascade that can cause symptoms such as headaches, cognitive difficulties, and fatigue. While pharmaceutical treatments often target single mechanisms, recent research has been exploring a broader, multi-pathway approach through nutritional supplementation. Key Findings: ➡ Comprehensive Nutritional Support: Nutrients like n-3 polyunsaturated fatty acids, sulphur amino acids, antioxidants, and minerals have shown promising potential in supporting recovery and mitigating the impact of concussions. These nutrients influence multiple neurophysiological pathways, providing a holistic approach to treatment. ➡ Innovative Approaches: Current human trials are investigating the efficacy of newer nutritional strategies, including probiotics, lactate, and amino acids, which could significantly enhance the management of sports-related concussions. ➡ Strategic Implications: The growing body of evidence underscores the potential of nutritional supplementation as a proactive strategy to prevent and reduce the long-term effects of concussions, thereby advancing athlete care and recovery protocols. This research is a crucial step toward understanding how we can use nutrition not just for recovery, but as a proactive measure to protect brain health in sports. Link to the Paper: https://lnkd.in/dmVmRdSG #SportsMedicine #ConcussionResearch #NutritionalIntervention #AthleteCare #CompleteBalanceHealth

Lachance Broiler Nutrition | SCI The negative impacts of heat stress (HS) on growth performance and lipid metabolism have been reported, but there are still no effective nutritional strategies to alleviate heat stress. Bile acids are new for their antioxidative properties and regulatory effect on lipid metabolism.  This study was carried out to evaluate the growth performance and lipid metabolism in chickens under heat stress when fed with bile acid supplements in their diet. The results showed that mild heat stress (32 °C) induced hepatic lipogenic gene (hepatic SREBP-1c) expressions and lipid deposition, without obvious tissue damage in broilers. Dietary supplementation of bile acid could decrease hepatic lipid deposition without affecting endogenous bile acid biosynthesis. Therefore, bile acid supplements can benefit broiler chickens during high ambient temperatures, serving as a new nutritional strategy against heat stress. check more information：https://lnkd.in/gwd74HX #HeatStress #broiler #Lachance_bileacids