AOFAS Journals’ Post

Great talk by #CAPKR PhD researcher Alex Foster-Powell on Leveraging machine learning to evaluate animal models of Alzheimer’s. 💡highlights include an introduction of workflow to evaluate the transalatability of various animal models for Alzheimer’s disease and validated the workflow with drug treated mice The University of Manchester #CAPKR #Alzheimers #Alzheimerresearch #animalmodels #machinelearning

Explore the animal cell! The nucleus, mitochondria, and ribosomes each play a vital role in keeping life going. #VAVAClasses #NEET #NEETBiology #AnimalCell #ScienceExplained #BiologyBasics

Out-of-midline needle insertion is the most common reason for needle-bone contact when performing interlaminar lumbosacral (LS) or sacrococcygeal (SC) epidurals in small animals. To correct this, withdraw the needle slightly and tilt it towards the midline.

SAVE THE DATE! Exciting news for those interested in alternative large animal models! Join us for a one-day scientific conference to discuss minipig care, handling, and use in biomedical research. Register now: https://lnkd.in/dcibBeg9 #ScientificConference #MinipigResearch #BiomedicalResearch #AnimalModels

Autonomix today announced the milestone achievement of design lock for its radio frequency (“RF”) ablation catheter specifically designed to ablate nerves transvascularly in targeted areas following the successful completion of animal testing. For details: https://bit.ly/3ZllOK3

Do fish feel pain? Scientific evidence from a brain damaged human patient shows the answer is YES. Ken Williford from the The University of Texas at Arlington, David Rudrauf from Université Paris-Saclay and Phil Halper, lead author of "Against Neo-Cartesianism: Neurofunctional Resilience and Animal Pain" explain how a human patient with damage to their prefrontal cortex - the area of the brain that is associated with self-awareness and emotion - confirmed that fish do, in fact, feel pain. Watch the whole programme on YouTube at https://lnkd.in/dTAEvB8a. #AnimalPain #animalbehavior #AnimalWelfare #fishwelfare #fishbehavior #fishcare

I’ve just attended a very interesting seminar on reviewers’ bias for animal models. The seminar was promoted by Johns Hopkins Center for Alternatives to Animal Testing (CAAT). The speaker, Catherine E. Krebs, presented data indicating that the bias is real and provided interesting suggestions on how to handle it. This might be of use for scientists relying on the latest in vitro models, organoids, spheroids, human-on-chip who might have at some point in their career experienced this bias from manuscript and grant reviewers requesting additional, unnecessary, in vivo experiments to corroborate their findings. More information can be found at: AnimalMethodsBias.org ckrebs@pcrm.org

Join us in 24 hours to learn more about NASH animal model development! https://buff.ly/3vOToNZ Register now and join tomorrow (Monday April 22, 2024): "Webinar: A New Obesogenic NASH Model with High Clinically Translational Power" #DrugDiscovery #DrugResearch #DrugDevelopment #NASHModels #AnimalModels #PhenotypicModels #BioDuro-Sundia

New 3i Investigator Article Alert!! Alternating Magnetic Fields AMF) and Linezolid Reduce Staphylococcus aureus Biofilm in a Large Animal Implant Model https://lnkd.in/gVrVbRvr