ANTECH Asia’s Post

The BIOFIRE® FILMARRAY® Gastrointestinal (GI) Panel is a state-of-the-art multiplex PCR test that can potentially help labs reduce costs and improve resource management. The BIOFIRE GI Panel may contribute to optimized lab efficiency thanks to: 🧪 Two minutes of hands-on time 🧪 Scalable throughput 🧪 Answers on 22 probable pathogens in about an hour Read how the BIOFIRE GI Panel can be an effective asset in your lab: https://lnkd.in/ghb9jTyk

Dear Colleagues, I wanted to share with you a recent publication in the American Journal of Case Reports that highlights an extremely rare case of empyema caused by Actinomyces naeslundii (A. naeslundii). The patient presented with fever and dyspnea, leading to a diagnosis of left thoracic empyema. Through visual examination and anaerobic culture, A. naeslundii was identified, emphasizing the importance of diagnostic techniques. The case also underscores the significance of long-term antibiotic therapy in treating Actinomyces empyema. This report expands our understanding of this rare condition and provides valuable insights for clinical practice. The complete report is now available on the American Journal of Case Reports webpage. | https://lnkd.in/dAHfezNY

Great article from my team in collaboration with Profs Dorte Frees and Heike Broetz-Oesterhelt We describe the mode of action of ticagrelor against bacteria, including MRSA and VISA and highlight the potential clinical benefits when combin ed with vancomycin or daptomycin

Of all the laboratory tests in #Hemostasis, #Lupus Continues to remain the connecting link between basic tests and specialized assays. At the same time, this is one of the test parameters that is significantly affected by all three - pre-analytical, analytical and post-analytical variables Please join us as we discuss the Best practices and clinical troubleshooting in Lupus (LA) Testing in our 22nd Session of #ILluminationSeries Link to register- https://lnkd.in/gv45SQGB #SpecializedDiagnosis #PoweringPatientCare Dr Ajay Gandhi Bharat Sharma

Dear Colleagues, I wanted to share with you a recent publication in the American Journal of Case Reports that highlights an extremely rare case of empyema caused by Actinomyces naeslundii (A. naeslundii). The patient presented with fever and dyspnea, leading to a diagnosis of left thoracic empyema. Through visual examination and anaerobic culture, A. naeslundii was identified, emphasizing the importance of diagnostic techniques. The case also underscores the significance of long-term antibiotic therapy in treating Actinomyces empyema. This report expands our understanding of this rare condition and provides valuable insights for clinical practice. The complete report is now available on the American Journal of Case Reports webpage. | https://lnkd.in/dqJ9TuaA

Adaptive immune response regulation via the de novo sphingolipid biosynthetic pathway, an interesting study by THIRUVAIMOZHI et al. 2024. Glad to be part of this paper, and my heartiest congratulations to everyone https://lnkd.in/dJs7-fGp

In an era of ever-increasing rates of antifungal resistance, with C. auris posing a particular threat, new antifungal agents in the armamentarium are much needed. Ibrexafungerp is one of the new antifungals that has been found to be promising beyond its current role for vulvovaginal candidiasis including recurrent cases, all while being orally administered with excellent bioavailability. In this review article, we delve into this interesting antifungal agent's mechanism of action, pharmacokinetic/dynamic properties, and review the results of trials performed so far, as well as real-world data. https://lnkd.in/gux_VEbh

The final work from my postdoc at @TheCIMR in Rubinsztein lab is out today! We show how VCP shuttling and its local functions in cytosol and nucleus are fine-tuned by p37. Important insight into VCP diseases @CureVCPDisease https://lnkd.in/dJjDm-JB

Diagnosing #MantleCellLymphoma can be challenging due to the variety of morphologic variants. Cases are typically diagnosed with diffuse cyclin D1 positivity by IHC or FISH for t(11;14). Rare cases that are negative for cyclin D1 for t(11;14) are positive for SOX11 by IHC.

Check out our most recent preprint on bioRxiv by Cuong Tran, Zahra Zubair-Nizami and Ingeborg Langohr - "The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity."