Aurogene Srl’s Post

اعلام موقعیت تحصیلی در مقطع دکتری در حیطه Cancer Biology در University of California San Diego, America حیطه فعالیت استاد: Understanding how living cells migrate in reliable and orchestrated ways is essential to understanding the most fundamental functions of life. Cell migration is a complex behavior that emerges from the interactions of tens of thousands of molecular parts. Still, much of what is known is limited to the context of cell migration on artificial 2D environments. Through the development of quantitative microscopy and imaging techniques, three-dimensional matrix engineering, and molecular engineering, the Fraley Lab is advancing migration research into the third dimension. جهت کسب اطلاعات بیشتر و تماس با استاد به وبسایت زیر مراجعه نمایید: https://lnkd.in/d5evY34F #PhDposition #PhD #biomedicalengineering #fullfunded #fullfund #university #cancerbiology #biomedicalscience #biology #cancercellmigration #academicresearch

In today’s #ThursdayDiscovery, we’re highlighting a best-practices framework for spatial biology studies using GeoMx DSP. The authors demonstrate how digital spatial profiling can be optimized to overcome tissue sample constraints and enhance biomarker discovery. This framework empowers researchers to maximize insights from limited samples in spatial biology.   Visiopharm's Oncotopix® Discovery software was key to the image analysis process, specifically in selecting regions of interest (ROIs) and segmenting tissue compartments for precise analysis.   If you work in spatial biology or drug discovery, this is essential reading! 👉 Read the full article: https://lnkd.in/gCpMJDfy Congratulations Espy Anguiano, PhD, MS-MBA for moving this project forward, and all the authors David Krull, Premi Haynes, Anil Kesarwani, PhD, Julien Tessier, Benjamin Chen, MD, PhD, Kelly Hunter, Deniliz Rodriguez, Yan Liang MD PhD, James R. Mansfield, Maxine McClain, Corinne Ramos, Edward Bonnevie, NanoString Technologies, Inc. 👏 #SpatialBiology #SpatialOmics #OncotopixDiscovery

𝗦𝘆𝗻𝗰𝗿𝗼𝗣𝗮𝘁𝗰𝗵 𝟯𝟴𝟰: 𝗖𝗮𝗿𝗱𝗶𝗳𝗳’𝘀 𝗡𝗲𝘄 𝗚𝗮𝘁𝗲𝘄𝗮𝘆 𝘁𝗼 𝗜𝗼𝗻 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 🔬 🎉 Exciting news! The SyncroPatch 384 Instrument Grant 2023 has been awarded, and the recipients at Cardiff University’s Medicines Discovery Institute are already advancing their research project with this cutting-edge technology. The SyncroPatch 384 is set to be a game-changer in the project “Enabling Hit Identification and Early Structure-Activity Generation for Novel Ion Channel Targets.” This initiative is lead by a team of experts including John Atack, Helen Waller-Evans, Emyr Loyd-Evans, and Oana Popa, focusing on innovative lysosomal research. A snapshot captures the moment Karen Elvers and Iwan Williams complete their hands-on training on the SyncroPatch 384, expertly guided by our skilled application scientist, Nicoletta Murciano. We can’t wait to see the groundbreaking research questions that will be answered, and the accelerated projects made possible by the SyncroPatch 384. 🚀 We look forward to seeing how the SyncroPatch 384 will accelerate research at Cardiff University. The best of success in your scientific endeavors! #PatchClamp #APC #Electrophysiology #IonChannels #Lysosomal #Research #SyncroPatch384

𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗯𝗶𝗼𝗹𝗼𝗴𝘆 paints a vivid picture of cellular interactions, guiding us toward the next generation of targeted therapies. At IRBM, we harness the power of spatial biology to decode these interactions, offering deeper insights into cellular behavior and therapeutic potentials. Our latest white paper, 𝙄𝙣𝙨𝙞𝙜𝙝𝙩𝙨 𝙛𝙧𝙤𝙢 𝙎𝙥𝙖𝙩𝙞𝙖𝙡 𝘽𝙞𝙤𝙡𝙤𝙜𝙮 𝙞𝙣 𝘿𝙧𝙪𝙜 𝘿𝙞𝙨𝙘𝙤𝙫𝙚𝙧𝙮 𝙖𝙩 𝙄𝙍𝘽𝙈: 𝘛𝘩𝘦 𝘐𝘮𝘱𝘢𝘤𝘵 𝘰𝘧 𝘊𝘦𝘭𝘭𝘶𝘭𝘢𝘳 𝘌𝘤𝘰𝘴𝘺𝘴𝘵𝘦𝘮𝘴, showcases how our advanced imaging techniques and analyses uncover critical insights for innovative drug development. 🎨Dive into the colorful world of spatial biology by downloading the white paper now! Learn how our capabilities are helping translate these discoveries into progress across different therapeutic areas. #DrugDiscovery #SpatialBiology #IRBM

#Webinar: Working with #mouse models means coping with very small sample volumes. Learn how to safe on precious samples while simultaneously increase data output and with this use highly valuable resources way more sustainable. The Proximity Extension Assay (PEA) Technology by Olink Proteomics utilizes only 1µL sample measuring 43 #Cytokines / #Chemokines in parallel in mice. February 29, 2024 - 3 PM CET #translational #science #preclinical #research

Come learn about the PhenoCycler-Fusion and PhenoImager HT and how our local academic and biotech scientists are using them to accelerate their spatial biology research! All are welcome to join for some or all of the talks. Check out the agenda!

Yesterday we wrapped up the Introductory Module of our Flow Cytometry Workshop: From Basics to Advanced Applications 2nd Edition! 🎉 Huge thanks to everyone who joined us—it's been an amazing journey so far! 🙌 Now, onto the Advanced Module for even more insightful talks and hands-on experiences! 💡 Let's dive deeper into the world of flow cytometry together! 💪 #FlowCytometry #AdvancedModule #ScienceCommunity Alexandre Salvador Emília Cardoso Rui Gardner Ana Leda F. Longhini, PhD Mariana Fernandes Diogo Silvério Denise Brito i3S - Instituto de Investigação e Inovação em Saúde

I wanted to share some reflections on the PSDI 2024 - 32nd Protein Structure Determination in Industry Meeting, which I attended with my colleague Amandine Gontier, Technical Consultant for NanoTemper Technologies, Team South Europe. I hope this overview isn’t too lengthy for LinkedIn standards 😊 First, the meeting took place in beautiful #Paris. It was an incredible three days with 27 speakers from companies, CROs, and academia, and around 200 attendees, all driven by a passion for science—especially #structuralbiology and #biophysics! The meeting covered a wide range of topics, divided into six sections: 1) Emerging Therapeutic Methods in Drug Discovery. I found @George Petzold’s talk on novel #CRBN neosubstrates and Paraskevi (Evi) Gkeka’s presentation on a new method to identify RNA binding sites especially inspiring. 2) Cryo-EM Advancements in Sample Preparation & Data Processing. Gergely Papp’s work developing EasyGrid to automate #CryoEM sample prep and imaging control was particularly innovative. 3) Challenging Targets: Cryo-EM of Membrane Proteins. Fantastic insights from Christian Löw on solute carriers and Dietmar Weichert on the #GPCR receptor, GPR55. 4) Structural Biophysics. Great to hear how Domainex, represented by Nathan Zaccai, is tackling challenging ion transporters. 5) Structural Biophysics: NMR in Structure-Based Drug Discovery (SBDD). Inspired by @Donald Rieck ’s quest to make NMR faster and cheaper for high-throughput screening and Roberto Maya Martinez’s work on using NMR to identify cryptic pockets. 6) Synergies between AI & Experimental Approaches Casper Goverde presented an exciting approach for designing soluble analogs of integral membrane proteins, while @Arwen Pearson shared how X-ray crystallography will evolve. It was also rewarding to see so many presentations featuring data generated with NanoTemper Technologies’ instruments, including #Prometheus & #Monolith (#nanoDSF, and #MST). Looking forward to the continued innovations in this field, and thanks to the organizers Sonja K., and Tatiana Isabet for having organized this fantastic meeting. See you in #Basel in 2026?

Light on – light off: the test result is ready💡 But how does the OptoAssay system work? We prepared a video demonstrating the preparation and measurement process, please enjoy watching 🤩 Explore our research article here (Open Access): https://lnkd.in/eKKGb-r4 Science Magazine INM-Leibniz Institute for New Materials University of Freiburg Nadine Urban Maximilian Hörner Wilfried Weber #optogenetics #bioassays #pointofcare #diagnostics #syntheticbiology

#ESCCA 2024 in Palma de Mallorca is going to start tomorrow! Please feel free to connect with the Beckman Coulter Life Sciences team, it will be our pleasure to discuss recent developments and to learn from you about your needs. Also, please don’t miss the scientific poster session, where our colleagues from R&D and Marketing will present the following topics (abstract numbers in parentheses): ·       A new automated flow cytometry method for #CD34+ hematopoietic stem and progenitor cell enumeration and analysis (HEM-18), ·       New anti-#TRBC2 (TCR Cβ2) antibody conjugates to simplify T-cell clonality research and assessment (HEM-44), ·       Method Agreement Performance Study of the #DxFLEX ClearLLab 10C Application System (HEM-57), ·       Precision performance of the DxFLEX ClearLLab 10C Application System (HEM-65), ·       Standardization of the #ClearLLab 10C Panel on a DxFLEX Flow Cytometer: A Comprehensive Study (HEM-66), ·       Toward Standardized AML-MRD Assessment In Clinical Research Studies And Trials Using Dry Antibody Panels (#DURA Innovations) (IMM-07), ·       Easy-to-use functional Natural Killer (NK) cells assay and associated stimulation reagent (IMM-08), ·       Development of new single-color reagents for flow cytometry fulfilling requirements from the In Vitro Diagnostic Device Regulation (#IVDR) (OTH-09), ·       New #supervised automatic analysis faithfully replicates expert manual gating for flow cytometric immune cell subset identification (OTH-10), ·       A fully automated, walkaway flow cytometry #workflow for immune cell subsets identification (OTH-11), ·       #CellMek SPS Instrument Performance: Gated populations with automated vs. manual sample prep using a 10-color antibody panel (OTH-16). I also would like to highlight the posters by Rarity Bioscience : ·       Ultra-sensitive molecular MRD by flow cytometry using superRCA mutation assay for NPM1 positive AML patients (HEM-46), ·       NRAS, WT1, NPM1 and IDH mutation detection for molecular MRD-assessment using Flow Cytometry in pediatric AML (HEM-51), ·       Use of the new superRCA mutation assay for molecular MRD monitoring using flow cytometry in pediatric AML (HEM-71). I look forward to seeing you!