Can Dincer’s Post

📚 Seeing is believing: Download this complimentary Article Collection today! 🔬 Imaging is one of the foundational techniques used in the life sciences. From imaging the expression of individual proteins or genes in single cells to the screening of drugs in multi-well plates, microscopy platforms for cellular imaging are integral tools for unravelling the complexities of biological systems. 🙋♀️ This free article collection from Wiley showcases a diverse range of studies that employ our EVOS Cell Imaging Systems (Thermo Fisher Scientific). What You Will Learn: 👉 Exploring K5 peptide’s role in improving protein delivery into cells 👉 Identifying cell receptors using fluorescent ligands 👉 Assessing crosslinking effects on collagen-elastin scaffolds for wound healing 👉 Investigating miRNAs’ effects on GCTB cell proliferation and movement 👉 Versatility of EVOS Cell Imaging Systems across multiple research fields 🤓 More info: https://lnkd.in/epkBGb5u #EVOS #imaging #thermofisherscientific

𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗯𝗶𝗼𝗹𝗼𝗴𝘆 paints a vivid picture of cellular interactions, guiding us toward the next generation of targeted therapies. At IRBM, we harness the power of spatial biology to decode these interactions, offering deeper insights into cellular behavior and therapeutic potentials. Our latest white paper, 𝙄𝙣𝙨𝙞𝙜𝙝𝙩𝙨 𝙛𝙧𝙤𝙢 𝙎𝙥𝙖𝙩𝙞𝙖𝙡 𝘽𝙞𝙤𝙡𝙤𝙜𝙮 𝙞𝙣 𝘿𝙧𝙪𝙜 𝘿𝙞𝙨𝙘𝙤𝙫𝙚𝙧𝙮 𝙖𝙩 𝙄𝙍𝘽𝙈: 𝘛𝘩𝘦 𝘐𝘮𝘱𝘢𝘤𝘵 𝘰𝘧 𝘊𝘦𝘭𝘭𝘶𝘭𝘢𝘳 𝘌𝘤𝘰𝘴𝘺𝘴𝘵𝘦𝘮𝘴, showcases how our advanced imaging techniques and analyses uncover critical insights for innovative drug development. 🎨Dive into the colorful world of spatial biology by downloading the white paper now! Learn how our capabilities are helping translate these discoveries into progress across different therapeutic areas. #DrugDiscovery #SpatialBiology #IRBM

𝗖𝗘𝗟𝗟𝗟𝗜𝗠𝗔 𝗧𝗔𝗟𝗞𝗦 𝗩 𝗚𝘂𝗮𝗿𝗱𝗶𝗮𝗻𝘀 𝗼𝗳 𝗵𝗲𝗮𝗹𝘁𝗵: 𝗧𝗵𝗲 𝘀𝘁𝘂𝗱𝘆 𝗼𝗳 𝗶𝗼𝗻 𝗰𝗵𝗮𝗻𝗻𝗲𝗹𝘀 𝗶𝗻 𝗲𝗮𝗿𝗹𝘆 𝗱𝗿𝘂𝗴 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆. Join us for an exclusive conversation with @𝗧𝗵𝗼𝗺𝗮𝘀 𝗠𝘂̈𝗹𝗹𝗲𝗿, a distinguished scientist with over 30 years of experience in ion channel research. https://lnkd.in/eBwc5MqX 🌍 From neural activity to muscle contraction: Ion channels play a key role. Learn from Thomas Müller how these fascinating structures impact modern medicine. Whether you're an experienced researcher, a biology student, or simply curious about the latest advances in science and medicine, this webinar promises to inspire and inform. Don't miss this opportunity to gain insights from a leading expert and explore the future of ion channel research. Register now and be part of this exciting event that bridges science and innovation! https://lnkd.in/e_JMdfiE 𝘛𝘩𝘦 𝘤𝘰𝘯𝘷𝘦𝘳𝘴𝘢𝘵𝘪𝘰𝘯 will be 𝘪𝘯 𝘎𝘦𝘳𝘮𝘢𝘯 𝘸𝘪𝘵𝘩 𝘴𝘪𝘮𝘶𝘭𝘵𝘢𝘯𝘦𝘰𝘶𝘴 𝘌𝘯𝘨𝘭𝘪𝘴𝘩 𝘵𝘳𝘢𝘯𝘴𝘭𝘢𝘵𝘪𝘰𝘯 𝘰𝘯 𝘢 𝘴𝘦𝘤𝘰𝘯𝘥 𝘢𝘶𝘥𝘪𝘰 𝘵𝘳𝘢𝘤𝘬. #cellbiology #drugdiscovery #research #healthcare @CELLIMA

Today, Precede Biosciences launched our #BehindtheScience video series, which provides a brief video synopsis of new data we're presenting at #AACR24. Watch Matthew Eaton, PhD, our Vice President of Computational Biology, describe key takeaways for the abstract on the proof-of-concept study for our comprehensive epigenomic #LiquidBiopsy platform. #PrecisionMedicine #PrecisionOncology #Healthcare #DrugDevelopment #ADCs View data: https://bit.ly/49pPc56

In today’s #ThursdayDiscovery, we’re highlighting a best-practices framework for spatial biology studies using GeoMx DSP. The authors demonstrate how digital spatial profiling can be optimized to overcome tissue sample constraints and enhance biomarker discovery. This framework empowers researchers to maximize insights from limited samples in spatial biology.   Visiopharm's Oncotopix® Discovery software was key to the image analysis process, specifically in selecting regions of interest (ROIs) and segmenting tissue compartments for precise analysis.   If you work in spatial biology or drug discovery, this is essential reading! 👉 Read the full article: https://lnkd.in/gCpMJDfy Congratulations Espy Anguiano, PhD, MS-MBA for moving this project forward, and all the authors David Krull, Premi Haynes, Anil Kesarwani, PhD, Julien Tessier, Benjamin Chen, MD, PhD, Kelly Hunter, Deniliz Rodriguez, Yan Liang MD PhD, James R. Mansfield, Maxine McClain, Corinne Ramos, Edward Bonnevie, NanoString Technologies, Inc. 👏 #SpatialBiology #SpatialOmics #OncotopixDiscovery

Join us for our free webinar on Wednesday 4 December 2024 at 4.00pm (GMT) - Using the HaloTag® and Janelia Fluor® Dyes for Live Cell Single Molecule Imaging. Live cell single-molecule imaging is a powerful approach to analyse the sub-cellular dynamics and biochemical properties of biomolecules in their endogenous context. Single-molecule methods have the unique capability to dissect the molecular heterogeneity underlying biological processes. Instead of observing the average behaviour of an ensemble of macromolecules, single-molecule experiments can identify sub-populations of molecules with distinct biochemical properties. Therefore, this approach has the power to uncover an entirely unexplored layer of cell biology and will reveal novel biological concepts that challenge existing paradigms. Single-molecule detection of proteins in living cells requires the sparse labelling of the target protein with bright, photostable fluorophores. The combination of the HaloTag®, which forms a covalent bond with its ligand, with cell permeable Janelia Fluor® dyes allows the titratable, intracellular labelling of the tagged protein to achieve single-molecule detection. In this webinar our featured speaker Dr. Jens Schmidt from Michigan State University, will outline the scientific questions single-molecule imaging can address, the equipment required to carry out the experiments, and best practices for using the HaloTag® and Janelia Fluor® dyes to generate the best data. Register at https://bit.ly/4fMUN9m to secure your place. #MolecularImaging #ProteinTagging #CellularImaging

Join us for our free webinar on Wednesday 4 December 2024 at 4.00pm (GMT) - Using the HaloTag® and Janelia Fluor® Dyes for Live Cell Single Molecule Imaging. Live cell single-molecule imaging is a powerful approach to analyse the sub-cellular dynamics and biochemical properties of biomolecules in their endogenous context. Single-molecule methods have the unique capability to dissect the molecular heterogeneity underlying biological processes. Instead of observing the average behaviour of an ensemble of macromolecules, single-molecule experiments can identify sub-populations of molecules with distinct biochemical properties. Therefore, this approach has the power to uncover an entirely unexplored layer of cell biology and will reveal novel biological concepts that challenge existing paradigms. Single-molecule detection of proteins in living cells requires the sparse labelling of the target protein with bright, photostable fluorophores. The combination of the HaloTag®, which forms a covalent bond with its ligand, with cell permeable Janelia Fluor® dyes allows the titratable, intracellular labelling of the tagged protein to achieve single-molecule detection. In this webinar our featured speaker Dr. Jens Schmidt from Michigan State University, will outline the scientific questions single-molecule imaging can address, the equipment required to carry out the experiments, and best practices for using the HaloTag® and Janelia Fluor® dyes to generate the best data. Register at https://bit.ly/4i9CwF6 to secure your place. #MolecularImaging #ProteinTagging #CellularImaging

Two weeks ago, I completed the 6 week lab based section of my research project, and what an incredible journey it has been! Throughout this experience, I had the opportunity to develop a range of laboratory skills, from tissue culturing to flow cytometry. My research focused on the specialisation of actin-based processes in Dictyostelium, providing me with valuable insights into cellular mechanisms. Now, I’m excited to move on to the next step: writing up the results! Attached is a PIP3 LifeAct of labelled Dictyostelium. #labproject #researchproject #Dictyostelium #dissertation

Been awhile since I last spoke in a conference, so I do look forward to sharing more on RareCyte, Inc.'s Orion platform which is a high-performance spatial biology platform designed for multiplexed tissue imaging. It allows researchers to visualize multiple biomarkers simultaneously in tissue samples with high spatial resolution, making it useful for studying tissue architecture, cell-cell interactions, and spatial context within the tumor microenvironment. Orion enables researchers to gain insights into complex cellular environments in oncology, immunology, and other fields requiring high-plex tissue imaging. Discover next generation spatial imaging! #SpatialbiologyCongress #SpatialBiology #RareCyte

Exciting news from Aurora Biomed! 🎉 We’re thrilled to introduce the ADNAP20 series 96 channel. In just 30 minutes automate 96 well sample plate. Designed to streamline your lab workflows, the ADNAP20 series offers high throughput and precision, ensuring consistent and reliable nucleic acid extraction every time. Whether you're working with blood, tissue, or cells, this system is your go-to for enhancing efficiency and accuracy in your molecular biology applications. Why choose the ADNAP20 series? 🔬 Automate your DNA/RNA purification with ease 🚀 Boost productivity with high sample processing capacity 📊 Achieve reproducible results across diverse sample types Ready to enhance your lab's capabilities? Discover how the ADNAP20 series can transform your research workflow! #LabAutomation #DNAPurification #MolecularBiology #ADNAP20 #liquidhandling #automation #RNAPurification #DNAPurification #NucleicAcidExtraction