VIB-KU Leuven Center For Brain & Disease Research’s Post

This afternoon, Eiman Azim, Ph.D., Associate Professor and William Scandling Developmental Chair at the Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, and Associate Adjunct Professor at UCSD's Department of Neurobiology, will give a talk on 'Sensorimotor Circuits for Dexterous Movement.' See the abstract here >

"Professor Benedikt Berninger delivers inaugural lecture "The Art of Forging Neurons" Professor Benedikt Berninger is a Professor of Developmental Neurobiology at the Centre for Developmental Neurobiology (CDN) and the MRC Centre for Neurodevelopmental Disorders (MRC CNDD). His research addresses the fundamental question of why neurons cannot regenerate or repair themselves when damaged. His group focuses on initiating neurogenesis in the adult mammalian brain, where neuron generation is typically impossible. Using neural reprogramming techniques, the group can convert support cells into neurons." Watch his inaugral lecture as a Professor of Developmental Neurobiology at IoPPN, here: https://lnkd.in/eBZ9g_Fg #KCL #IOPPN #Neuroscience #NeuroBiology #Neurons #NeurodevelopmentalDisorders #Science #Lecture

🔬 Welcome to the Laboratory of Molecular Neurobiology – LSMU University 🔬 We are excited to launch our official LinkedIn page! Our lab focuses on understanding the molecular mechanisms behind neurodegenerative and neuropsychiatric disorders. By exploring RNA-based markers such as miRNA in blood and extracellular vesicles, along with genetic variations, we aim to improve diagnosis and treatment outcomes. Additionally, our research investigates oxidative stress, aging, and drug interventions using animal models to gain deeper insights into disease progression and therapy. Follow us for updates on our latest discoveries and ongoing projects. Let’s explore the molecular mysteries of the brain together! 🧠✨ #Neurobiology #MolecularMarkers #RNAResearch #Neurodegeneration #LSMU #ExtracellularVesicles #OxidativeStress #AgingResearch #MolNeuroLT #Lithuania

Day 18th: Blog: Martyna Panasiuk, from the Centre of Developmental Neurobiology, King's College London, delves into precision techniques for targeting specific neuron populations in tissue slices, shedding light on strategies to enhance experimental accuracy. Read more https://buff.ly/3zPFhda #SciAdvent #patchclamp

🧠 Attention neuroscientists: we have new antibodies for you! Our catalog contains nearly 2000 antibodies for neuroscience research in a variety of applications including immunoprecipitation, western blot, multiplex IHC, and more. New additions to our neuroscience catalog include antibodies recognizing the following human proteins: - PAX8 - SOX2 - SET - KIF5A and KIF5B Visit our neuroscience hub to discover all antibodies for neuroscience targets, plus educational resources to support your neuroscience research! https://lnkd.in/dS85ED3D #neuroscience #neurobiology #neuro #antibodies #lifescience

Day 5: Scientifica has supported the Drosophila Neurobiology: Genes, Circuits & Behavior course at Cold Spring Harbor Laboratory with our #SliceScopes for several years - and we were given this wonderful insight into the course, techniques learnt and our collaboration. Find out more in our #ScientificaMeets series >> https://buff.ly/3WB8oZ3 #CSHLFlycourse #patchclamp #electrophysiology #SciAdvent

Still looking for antibodies to support your neuroscience research? 🧠 Find the antibodies you need in our extensive collection of nearly 2000 antibodies for neuroscience research. This includes antibodies against popular neuroscience targets including: -Neurofilament L (human/mouse/rat) -ASPH (human) -SOX10 (human) -Phospho-SMC3 (human, mouse) Visit our neuroscience hub to discover all antibodies for neuroscience targets, plus educational resources to support your neuroscience research. https://lnkd.in/dS85ED3D #neuroscience #neurobiology #neuro #antibodies #lifescience

We were thrilled to participate with our neuroscientists at the Federation of European Neuroscience Societies - FENS 2024 conference in #Vienna! The event was a hub of groundbreaking discussions and innovations in the field of #neuroscience, and our experts made significant contributions: ⚡ Spontaneous Activity in the Developing Cerebral Cortex Lodato Simona – Group Leader and Associate Professor at Humanitas University, delivered a special lecture on the role of spontaneous neuronal activity in cortical development. Her research, funded by the European Research Council (ERC), explores how different neuronal subtypes and their ion channel repertoires impact the formation of cortical circuits. These findings open new avenues for addressing developmental epilepsies. 🔬 Molecular Mechanisms of Synaptic Dysfunction in Angelman Syndrome Matteo Fossati – Junior Group Leader at Humanitas Research, presented pioneering research on Angelman Syndrome. His work delves into the role of the UBE3A gene in synaptic development, employing genetic engineering and advanced imaging techniques. 🧠 Maternal Immune Activation and Neurodevelopmental Disorders Davide Pozzi – Assistant Professor at Humanitas University, shared insights into how maternal immune activation can influence neurodevelopmental disorders (NDDs). His study highlights the role of prenatal IL-6 elevation in altering key processes in brain development. Understanding these mechanisms is vital for developing interventions to prevent NDDs.   We are proud of our researchers for their contributions to advancing our understanding of brain development! #FENS2024 #AngelmanSyndrome #NeurodevelopmentalDisorders #HumanitasResearch #humanitasuniversity #hunimed #humanitas #research

To revolutionize treatments for brain cancer and neurological disorders, we need precise control over neuron activity. For the past 18 months in Alice Ting's lab at Stanford, I've worked with Shizhong Dai to develop engineered ion channels that enable connection-specific neuronal modulation. This breakthrough holds significant potential for therapeutics and for advancing studies of cell and cell-type interactions. One of the major challenges in neuroscience is the lack of methods to study neural systems in a connection-specific manner. Despite the complexity of these systems, current approaches lack the precision needed to target specific neuronal connections. Our work aims to address this gap, offering a new pathway to better understand and manipulate neural circuits. I recently had the opportunity to present this research at the Stanford Genetics Retreat and am excited to further explore its potential in advancing therapeutic strategies and scientific discovery. #neuroscience #genetics #bioengineering #therapeutics #braincancer #neurologicaldisorders #research #stanford

👇👇👇 We would like to share this Review below which provides two novel contributions to the field: i) the first systematic comparative evaluation of the three modeling approaches applied to the same paradigmatic brain disorders, which define the opportunities and benchmarks for a xenografting-based translational research agenda in brain disorders; and ii) the integration in a coherent set of experimental designs of the latest technologies from areas that have so far progressed largely independently and that should now be brought to bear onto each other for transformative impact on human neurobiology