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As simple as 1 - 2 - 3! What a great new tool.

Exciting News for Cell Researchers! - Sartorius just introduced the #CellCelector Configuration Tool 👇 Whether you're working on #singlecell isolation, #colonypicking, or any other #cellbased application – its your ultimate companion to select the right components building a custom platform which suits your individual #research needs. Try It Today!

Recent publication as a first author ( 😊 ) from my PhD works shed light on the intricate mechanisms underlying vascular protection in diabetic individuals. In our study, we explored into the role of Angiotensin (Ang)-(1–7) and Telomerase reverse transcriptase (TERT) in stimulating vasoprotective functions of CD34+ hematopoietic stem/progenitor cells, crucial players in vascular health. https://lnkd.in/gvxPJRUM

How do human haematopoietic stem cells (HSCs) self-renew and engraft? A new study finds MYC target 1 (MYCT1) is a crucial human HSC regulator that moderates endocytosis and environmental sensing https://ow.ly/MibV50SbcsI

A study, conducted by Feng et al. (2024), demonstrates the promising potential of umbilical cord stem cells (hucMSCs) in treating heart failure with preserved ejection fraction (HFpEF). The researchers found that hucMSC treatment significantly improved heart function and reduced harmful cardiac remodeling in HFpEF, with repeated treatments showing greater effectiveness than a single dose. Additionally, in vitro studies confirmed that hucMSC-secreted factors help moderate damaging cardiac changes, primarily through the Akt/FoxO1 signaling pathway, which plays a crucial role in their protective effects. These results suggest that hucMSCs could offer a valuable therapeutic option for HFpEF, particularly with repeated administration. Read more: https://lnkd.in/dph5ppEA #stemcellsresearch #stemcelltherapy #heartfailure #mesenchymalstemcells #stemcellbanking #umbilicalcordstemcells

Help me Improve this Prompt   Share your Feedback here (takes only 1m): https://qr.ae/pstM0g 🔬 Curious about stem cell patches? Let's delve into their wonders and potential side effects. 🧪 While these patches offer exciting prospects for tissue repair and regeneration, it's crucial to understand their complexities. Here's what you need to know: Possible side effects: Inflammation at the application site Risk of infection Allergic reactions Tissue rejection 🌱 Despite these potential drawbacks, the advancements in stem cell technology continue to revolutionize medicine. Let's discuss in the comments: what are your thoughts on the future of regenerative medicine? 💬 #StemCells #RegenerativeMedicine #HealthcareInnovation #MedicalTechnology #Biotechnology #Healthcare #Science #Wellness #Research #FutureOfMedicine  

The recent study conducted by Yang et al. (2024) investigated using exosomes from umbilical cord stem cells to deliver a specific circular RNA for treating premature ovarian failure. Results show that this RNA, when delivered through the exosomes, reduces aging in ovarian cells. It achieves this by regulating cellular processes and improving ovarian function. The findings suggest a promising approach for treating premature ovarian failure and shed light on its underlying mechanisms.   Read more: https://lnkd.in/dpfacjB4

#HighlyCitedPapers   📝 Wnt/β-Catenin Signaling Activation Induces Differentiation in Human Limbal Epithelial Stem Cells Cultured Ex Vivo — Bisevac, et al.   In this paper, the authors aimed to test the effect of the small molecule LY2090314, a GSK-3 inhibitor and Wnt/β-catenin activator, on the cell fate of hLESCs expanded from healthy limbal biopsies cultivated ex vivo.   Full text is available 👇 https://lnkd.in/etUKuiSq   #medicine #health #research #science

Disease modeling of human pathologies in vitro using human pluripotent stem cells (hPSCs) is increasing in the scientific community. Read about this novel method of hPSC clonal isolation to improve and upscale the generation of edited hPSCs required for downstream applications including disease modeling and drug screening and the role that CellCelector played: https://ow.ly/9zMo50QQPHm #stemcells #CRISPR #automation #cellcelector #lifescienceresearch

The Cellcelector platform plays a pivotal role in this endeavor by offering precise and efficient cell isolation capabilities. Researchers can use Cellcelector to selectively isolate specific cell populations derived from human pluripotent stem cells, allowing for the creation of complex in vitro disease models that closely mimic the cellular heterogeneity observed in human tissues. By enabling the isolation of disease-relevant cell types with high purity and viability, Cellcelector facilitates the development of more accurate and physiologically relevant disease models, ultimately advancing our ability to study disease mechanisms and identify novel therapeutic targets. Click on the link below to explore further on the technology. #cellcelector #automation #CRISPR #hPSCs