Charnwood Discovery, part of Concept Life Sciences’ Post

Superbio X31Plex STR Detection Kit Catalog No.A00110-50,50 Reactions/Box 30 X-Chromosome STR Loci, 1 Sex Locus 1. Six-Color Fluorescent Labeling Technology: The kit uses six-color fluorescent labeling technology, with highly efficient fluorescent molecules (energy transfer) that provide high sensitivity. 2. Optimally Selected Loci: The selected loci have a high number of alleles, with evenly distributed common alleles. All loci are 4-5 nucleotide repeats, meeting the ideal conditions for forensic STR loci and suitable for STR-PCR multiplex amplification. 3. Highly Specific Primer Design: The design and selection of primers are highly specific, eliminating analytical errors due to homology. The entire set of primers is designed with uniform parameters to ensure consistent annealing temperatures, achieving amplification stability and balance. This allows for reproducible, sensitive, and parallel efficient amplification in multiplex PCR processes.

Review of #mRNA cap structures, cap analogs and NUDIX enzymes with known decapping activity (Nudt16, Nudt12, and Nudt2) that can be used as tools to characterize synthetic capped mRNAs.

Introducing ATCC Assay Ready Cells: From Frozen to Data in 1 Day! What is ATCC’s Assay Ready Solution? Assay Ready Cells are cryopreserved at a highly functional state, eliminating the need for prior cell culture. Just like most consumables, these cells can be used in your assays right after thawing. Learn More: https://buff.ly/3XSLexW #ATCC #AssayReadyCells #ResearchRevolution #ScienceInnovation

Here is a new and very significant application paper demonstrating the real power of differential mobility spectrometry coupled with acoustic droplet ejection - open port sampling interface - mass spectrometry (the Sciex Echo-MS) in the high throughput analysis, separation and quantitation of isomeric compounds in complicated biological reaction mixtures.

IDT Targeted RNA-Seq from FFPE samples highly degraded Effectiveness of the RNA-Seq lib prep method combining cDNA synthesis and single-stranded ligation strategy with xGen cfDNA & FFPE DNA lib prep https://lnkd.in/dzYr4xJg cDNA libraries constructed from severely degraded samples, RIN 1.3 or lower

Successfully completed a two day workshop on approaches on biochemical investigations held on 22nd & 23rd February 2024 . This workshop provided me with a comprehensive understanding of various biochemical investigational techniques, including: Qualitative analysis of biomolecules (monosaccharides, disaccharides, polysaccharides, proteins) Hematological studies (sample collection and preservation, separation of serum and plasma from blood, differential staining of RBCs and WBCs) Cytological studies (observation of different stages of mitosis and meiosis, calculation of mitotic and meiotic index)

Happy to share one of the last projects I worked on during my PhD in collaboration with J&J. I wanted to thank all the authors and colleagues in J&J for their effort and contributions. It was an amazing experience to learn and combine state of the art chemical technologies such as HTE, flow, and automation with our previously developed photoredox approaches on C(sp3)-C(sp3) bond formation. If you want to know more about how these technologies can optimize and accelerate the library synthesis of building blocks or drug-like molecules by using commercially available aldehydes click on the link below.

#callforreading #recommendations in Methods and Protocols MDPI Title: Studying miRNA–mRNA Interactions: An Optimized CLIP-Protocol for Endogenous Ago2-Protein Authors: Sophie Stebel, Janina Breuer and Oliver Rossbach from University of Giessen Read and Download for #free at: https://lnkd.in/g7Yj74XB #methods #protocols #geneexpression #protein #rnaseq #micro #rna #cell #uv #interaction

#DCRJournal visual abstract recap | on Cost-Effectiveness Analysis: Selective Use of Neoadjuvant Chemoradiation in Locally Advanced #RectalCancer: https://bit.ly/3ZfVdxu (link in bio)

DNA evidence and Forensic science DNA-based methods for human identification principally rely upon genotyping of short tandem repeat STR loci. Electrophoretic-based techniques for variable-length classification of STRs are universally utilized, but are limited in that they have relatively low throughput and do not yield nucleotide sequence information. High-throughput sequencing technology may provide a more powerful instrument for human identification, but is not currently validated for forensic casework. Here, we present a systematic method to perform high-throughput genotyping analysis of the Combined DNA Index System CODIS STR loci using short-read 150 bp massively parallel sequencing technology. Youtube video: https://lnkd.in/drdf8yDK #nikolaysgeneticslessons