COR2ED’s Post

📢 New insights in breast cancer (BC) from the EMERALD Trial subgroup analysis: ESR1 mutations and beyond!   Is elacestrant a game-changer for patients with ER+ metastatic BC who retain endocrine sensitivity despite acquired resistance? How can the findings from the latest subgroup analysis guide real-world clinical decisions in the second-line, post-ET+CDK4/6i?   📺 Join Dr Virginia Kaklamani as she reviews the latest subgroup analyses from the EMERALD trial, offering insights on:   ·      ER-driven progression post-ET+CDK4/6i ·      The impact of metastasis site, co-mutations (PIK3CA, TP53), HER2-low expression, and ESR1 variants (D538G, Y537S/N) on elacestrant’s efficacy and safety ·      The relevance of routine testing for ESR1 mutations via ctDNA at each disease progression This hypothesis-generating analysis provides key insights into personalised treatment strategies and the role of elacestrant in clinically relevant patient populations.   🔎 Are you curious about elacestrant’s efficacy and safety in complex settings, such as ESR1 and PIK3CA coexisting mutations?   Explore the discussion now and stay ahead in the evolving ER+/HER2- mBC treatment landscape.   📖 Want more details? Follow this link to learn more: https://lnkd.in/eXCweWwJ This programme has been sponsored by Menarini Stemline and is intended for healthcare professionals only. #MedicalEducation

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