Dharan Cancer Speciality Centre, Salem’s Post

Prognostic Significance of Tertiary Lymphoid Structures and Tumour-Infiltrating Lymphocytes in Clear Cell Renal Carcinoma A study investigated the characteristics and clinical significance of tertiary lymphoid structures (TLSs) and tumour-infiltrating lymphocytes (TILs) in clear cell renal cell carcinoma (ccRCC) across 1,286 patients. TLSs were present in 16% of tumours and associated with improved survival and therapy response, particularly when mature and dense. Conversely, high infiltration of scattered TILs predicted poor prognosis. The study highlighted the importance of immune infiltration patterns, showing that mature TLSs correlate with decreased relapse and death risks, whereas high TILs indicate worse outcomes, revealing complex immune dynamics in ccRCC. The link to the original article is in the comments. If you found this post valuable, give it a like and share it with your network! 😃 #CancerResearch #Immunotherapy #RenalCellCarcinoma #TertiaryLymphoidStructures #TumorInfiltratingLymphocytes #TLSs #TILs #ImmunoOncology Be at the forefront of cancer immunotherapy breakthroughs! 🔬 Subscribe for FREE to my monthly Newsletter for a dose of knowledge and the latest advancements: https://lnkd.in/ec5sV-iP  📧 #ImmunotherapyFrontiers #StayInformed #ImmunotherapyExploration #DontMissOut"

Tertiary Lymphoid Structures (TLSs) and Tumor Infiltrating Lymphocytes (TILs) - Prognostic Significance

Nasal and Sinus Cancer, a subtype of Head and Neck Cancer, originates in the tissue of the nose or sinuses. At Dharan Cancer Speciality Centre, we stand as a beacon of hope for those confronting this challenge, often linked to symptoms like persistent nosebleeds or nasal blockage—signs that should never be overlooked. With cutting-edge technology and a team of renowned Oncologists, we offer precise diagnostics and personalized treatment plans. From groundbreaking Radiation therapy to expert Surgical interventions, our multidisciplinary approach ensures every patient receives the highest standard of care. Timely detection and preemptive action are crucial in combating Cancer. If you experience persistent Nasal blockage, get screened for Nasal Cancer and safeguard your health by scheduling a screening today. #lossofsmell #nosebleeds #cancertreatment #cancerpatients #cancercare #cancercentre #ComprehensiveCancerCare #dharancancercare #nasalcare #sinusinfection #nasalandsinuscancer #sinuscancer #BestHospitality #getscreenedtoday #oncology #chemotherapy #nasalblockage #nasalandsinuscancer For Further Query #Call : +91 - 99439 39990 #Visit : https://lnkd.in/fqCzSnA

Whats your opinion? 👉 Rethinking Lung Cancer Screening in Never-Smokers A recent The Lancet correspondence by Wayne Gao and H Gilbert Welch raises pivotal concerns about lung cancer screening for never-smokers. Critiquing the TALENT study, they highlight the risk of overdiagnosis and unnecessary surgeries due to high detection rates that don't correlate with a reduction in mortality. The duo emphasizes the lack of evidence supporting the benefits of screening outweighing its harms. Their insights challenge current screening practices, urging a more evidence-based approach to benefit public health. #LungCancerScreening #PublicHealthPolicy #EvidenceBasedMedicine https://lnkd.in/dZVe2fsF

I recently had the opportunity to write an article for Endpoints News to shed light on one of the most significant medical needs for people affected by lung cancer with EGFR exon 20 insertion mutations—the need for new and effective first-line treatment options.   This mutation has historically responded poorly to many commonly used real-world first-line therapies for EGFR mutations. There is a tendency for rapid progression and inadequate outcomes among these patients, and thus a dire need for novel targeted approaches that can be used earlier in the course of treatment.  At Johnson & Johnson Innovative Medicine, the oncology team is leading the way in developing differentiated, immune-driven mechanisms of action and introducing new standards of care through a patient-centric research approach. Our hope is to transform the lives of people facing a lung cancer diagnosis.  Read the full article: bit.ly/3wCoPeM #MyCompany #LungCancer #NSCLC #TargetedTherapy 

Lung cancer is the leading cause of death around the world, and unfortunately, patients with non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations face inevitable disease progression.     Our priority at Johnson & Johnson Innovative Medicine is to challenge the current treatment landscape for these patients by developing unparalleled, personalized, targeted therapies for earlier intervention to create meaningful change.     Luca Dezzani wrote an incredibly impactful article for @Endpoints News, detailing the immense need for additional therapies and our patient-centric approach to helping solve these problems.     We believe lung cancer patients deserve better options for treatment. Learn more about how we plan to deliver at https://bit.ly/3xaoGiZ. #MyCompany #LungCancer #NSCLC #TargetedTherapy 

What are 5 facts about cancer? 1. Diverse Types: There are over 100 types of cancer, each named for the type of cell or organ in which it starts. Common types include breast cancer, lung cancer, prostate cancer, and colorectal cancer. 2. Global Impact: Cancer is a leading cause of death worldwide. According to the World Health Organization (WHO), it accounted for nearly 10 million deaths in 2020. 3. Early Detection Improves Outcomes: Early detection of cancer can significantly improve the chances of successful treatment. Screening methods such as mammograms, colonoscopies, and Pap smears can help detect cancer at an early stage. 4. Multiple Risk Factors: Cancer risk is influenced by a combination of genetic, environmental, and lifestyle factors. Some risk factors, like smoking and exposure to UV radiation, are preventable, while others, like genetics, are not. 5. Advances in Treatment: Significant progress has been made in cancer treatment over the past few decades. Modern treatments include surgery, chemotherapy, radiation therapy, immunotherapy, targeted therapy, and personalized medicine, which have improved survival rates and quality of life for many cancer patients. #CancerTypes #GlobalCancer #EarlyDetection #CancerRisk #CancerTreatment #IndiaCancerSurgerySite #India #CancerSurgeryHospital #LowCostCancerSurgery #BestCancerSurgeon 📌 For more information, you can contact us:- ✅Contact:- +91 9371770341 ✅Website:- https://lnkd.in/gknyN5jY ✅Email ID:-info@indiacancersurgerysite.com 👉 Watch Full Video:-

Big news in cancer screening! 🎉 The FDA has just approved a new blood test for colorectal cancer (CRC) screening. This breakthrough "Shield" test by Guardant Health offers a noninvasive alternative to traditional methods like colonoscopies and stool-based tests, making CRC screening more accessible. 🩸 Key points: ~ CRC is the second-leading cause of cancer-related deaths in the U.S. ~ Early detection is crucial, with a 91% five-year survival rate when detected early. ~ Screening rates are currently at 59%, below the 80% goal. ~ The ECLIPSE study demonstrated that the Shield test has 83% sensitivity for CRC detection and 90% specificity for advanced neoplasia. Dr. Daniel Chung from Massachusetts General Hospital highlights the importance of this approval, stating it will close the gap in screening rates and save more lives. Dr. William M. Grady from Fred Fred Hutch Cancer Center emphasizes the test's potential as an alternative for those who avoid current screening options. What are your thoughts on this advancement? How do you think it will impact CRC screening and patient compliance? Read the full article for more details: https://lnkd.in/eBuQdstX Let's discuss! 👇 #HealthcareInnovation #CancerScreening #ColorectalCancer #EarlyDetection #GuardantHealth #MedicalAdvancements #PatientCare

NOW ONLINE Being overweight after #ColorectalCancer diagnosis might affect your health. Read more in this special report by World Cancer Research Fund 🔓 OPEN ACCESS ➡️https://lnkd.in/gXMKSEuY The influence of adiposity on colorectal cancer prognosis remains poorly characterised. Here, as part of CUP Global, the evidence on post-diagnosis adiposity and colorectal cancer outcomes was systematically synthesised using standardised criteria, and a non-linear dose–response meta-analysis was conducted for the first time. Reverse J-shaped associations were observed between post-diagnosis BMI and all-cause mortality, colorectal cancer-specific mortality, and recurrence. Synthesised studies on other adiposity–outcome associations were limited in number and methodological quality. All evidence was graded as ‘limited—no conclusion’ for the likelihood of causality due to potential methodological limitations, calling for additional well-designed observational studies and intervention trials.

Exciting news for cancer patients and their loved ones! Introducing Cancertame, a revolutionary over-the-counter medicine for cancer. This broad-spectrum medication not only fights cancer cell growth but also helps reduce the harsh side effects of chemotherapy and radiotherapy. With Cancertame, patients can now have a more comfortable and manageable experience during their cancer treatment journey. No more worrying about the debilitating side effects, as Cancertame has covered you. This game-changing medicine is now available without a prescription, making it easily accessible for those in need. Say goodbye to expensive and hard-to-find medications, and hello to Cancertame. Join the fight against cancer and spread the word about Cancertame. Let's make this life-saving medicine known to all those who need it. Together, we can make a difference in the lives of cancer patients. #Cancertame #CancerTreatment #OverTheCounterMedicine #BroadSpectrum #FightCancer #ReduceSideEffects #Chemotherapy #Radiotherapy #ComfortableTreatment #AccessibleMedication #GameChanger #NoPrescriptionNeeded #Affordable #SpreadTheWord #LifeSaving #MakeADifference #CancerAwareness #Hope #Strength #Support