Croslyn Healthcare LTD’s Post

The renin-angiotensin-aldosterone system (RAAS) plays a vital role in regulating #bloodpressure and fluid balance. When activated, it narrows blood vessels and increases fluid retention, helping the body maintain stable blood pressure. While #exercise initially activates RAAS to ensure efficient blood flow, regular physical activity can lower its baseline activity. This helps reduce resting blood pressure and improve vascular health. Genetic makeup, including variations in the ACE and AGT genes, can influence how the body responds to RAAS activation and exercise. Individuals with certain genetic profiles may experience different blood pressure benefits from exercise. For those with genetic predispositions to hypertension, such as variations in #hypertension genes, exercise serves as a powerful tool to counteract these risks.

#Non_alcoholic_fatty_liver_disease (#NAFLD) and #metabolic_syndrome (#MetS) are intricately linked, sharing many pathophysiological mechanisms and contributing to each other's progression. #MetS is characterized by a cluster of conditions including #insulin_resistance (IR), central #obesity, #dyslipidemia, and #hypertension, all of which are major risk factors for #cardiovascular disease and type 2 #diabetes. The primary driver of #MetS is insulin resistance, often linked to visceral adiposity, which also plays a crucial role in developing NAFLD. #NAFLD represents a spectrum of liver conditions ranging from simple steatosis (fat accumulation) to non-alcoholic steatohepatitis (#NASH), which can progress to #cirrhosis and #liver_cancer. Fat distribution significantly impacts metabolic health. Subcutaneous adipose tissue (#SAT) is more metabolically benign than visceral adipose tissue (#VAT), closely associated with metabolic disturbances #Non_alcoholic_fatty_liver_disease #metabolic_syndrome #insulin_resistance #liver_cancer #cirrhosis #NAFLD REF: https://lnkd.in/dgDnP_S4 https://lnkd.in/dJgpsnFH

Unlock the power of personalized medicine with pharmacogenomics.🧬 Gain personalized insights into your genetic blueprint to better understand your risks for conditions like diabetes, hypertension, and more. Armed with this knowledge, you can make informed decisions to optimize your well-being and lead a healthier, more fulfilling life. Visit our website now(https://lnkd.in/gyM9taTg) and explore our customized DNA tests. #MensHealthMonth #GeneticTesting #HealthPotential #DiabetesAwareness #HypertensionPrevention #HealthyLiving #MensHealthAwareness #GeneticInsights #WellnessJourney  #MyDNA #MyDNAGeneProactive #MyDNAGeneProactivekids #GeneticWellness #NewBeginnings  #GeneticWellness #UnlockYourGenes #GeneticInsights #HealthyGenes #GeneticTesting #CancerPrevention #HealthEmpowerment #HealthJourney #KnowledgeIsPower #PreventiveHealth #EarlyDetection #ProactiveHealth #WellnessWednesday

Is there a potential for anakinra & pioglitazone in protein metabolism for patients on maintenance hemodialysis? Dive into the findings of a recent randomized pilot trial. Join us as we explore potential advancements in managing protein-energy wasting.#HealthcareResearch https://lnkd.in/gCruDHZw #MedicalTrials #ChronicInflammation #InsulinResistance #DialysisCare #PatientOutcomes #SCWD #Sarcopenia #Cachexia #WastingDisorders

[𝐁𝐥𝐨𝐠] Are you interested in #cellular #metabolism? Quantifying intracellular pyruvate is now easier then ever using Pyruvate-Glo™ Find out more in our latest blog where we discuss the current understanding of #pyruvate metabolism, it’s production and its disease implications. Read more at: https://bit.ly/3v9LvlP #energymetabolism #labchat

🔔Metabolism has emerged as a major driver of fibrotic diseases and provides new therapeutic options‼️ 👉Read more about metabolism and bioenergetics in the pathophysiology of organ fibrosis https://lnkd.in/d-F_ynBe

🌿 Understanding MTHFR Mutation: PART 1: A Patient's Path: Listen to the story of Dr. Mirhashemi's patient, who has faced symptoms since 2011 and is finding hope and healing. We're here to help unravel these mysteries and support your journey to better health. 💪 #MTHFRMutation #Folate #Metabolism #RareDisorders #PatientCare #healthjourney

📢A new #review #article shows evidence of an association between low #water intake and the risk of developing type 2 #diabetes or hyperglycemia (T2D/H). The authors propose several mechanisms to elucidate this relationship: • Increased circulating arginine vasopressin (AVP) results in hyperglycemia, promote gluconeogenesis and elevate plasma glucagon concentration. • Increased blood aldosterone concentration disrupts insulin signaling, hindering effective glucose removal from the bloodstream. • Cellular metabolism may undergo alterations, potentially leading to insulin resistance. 💧Explore further the relationship between T2D/H and water intake within the complete article below: https://lnkd.in/d8QiWjx2

[𝐁𝐥𝐨𝐠] Are you interested in #cellular #metabolism? Quantifying intracellular pyruvate is now easier then ever using Pyruvate-Glo™ Find out more in our latest blog where we discuss the current understanding of #pyruvate metabolism, it’s production and its disease implications. Read more at: https://bit.ly/3TwOIVS #energymetabolism #labchat

🐔 Aflatoxin B1 impairs liver function, induces oxidative stress and disrupts cellular pathways, potentially worsening bone health. 📑 This study revealed that broilers exposed to #AFB1 suffers lameness and other bone disorders by impairing #bonemineralization through the disruption of the #vitaminD receptor and #calcium and phosphorus transporters. ⬇ Follow this link to read the complete article: https://lnkd.in/dCiRGzSp #BIŌNTE  #mycotoxins #animalnutrition