Curio Bioscience’s Post

ICYMI: Recent advancements in #spatial #omics have transformed genomics, allowing us to analyze cellular function within their native tissue environment. However, challenges like noise and limited resolution hinder current methods. Our recent blog explores a novel technique that overcomes these limitations. Read more: https://lnkd.in/dnmktd7w #SpatialTranscriptome #multiomics #singlecell

Breakthroughs are transforming #multiomics research with the emergence of spatial omics. This innovative approach adds a crucial dimension to our understanding of biological systems by mapping molecular information directly onto tissue structures. Spatial omics technologies, including spatial transcriptomics and imaging mass spectrometry, allow visualization and analysis of #gene, #protein, and #metabolite distribution within tissues. This spatial resolution reveals intricate cellular interactions, microenvironmental influences, and tissue heterogeneity previously obscured in bulk analyses. The impact of #spatialomics extends across multiple areas: enhancing our grasp of disease progression and treatment responses, improving drug discovery and development, enabling more precise cell type identification, and deepening our insights into developmental biology and organ function. However, integrating spatial data with traditional omics datasets presents new bioinformatics challenges. As we explore this new frontier, questions arise: How can we effectively combine and interpret this wealth of spatially resolved molecular information? How will spatial omics reshape various research fields and drive innovation in personalized medicine and drug discovery? https://lnkd.in/dkuEcGTW #SpatialOmics #Multiomics #Biotech #ResearchInnovation #PersonalizedMedicine

Happy Monday everyone! Today's blog dives deeper into a new method - published in Nature - called Slide-tags. It's changing spatial omics by capturing single-cell data with high-resolution location information. Imagine the ability to analyze single cells across multiple layers - their genes (transcriptomics), regulatory mechanisms (epigenomics), and proteins (proteomics) - all while pinpointing their exact location within the tissue! #SingleCell #SpatialTranscriptomics #Bioinformatics

Recent advancements in spatial omics have transformed genomics, allowing us to analyze cellular function within their native tissue environment. However, challenges like noise and limited resolution hinder current methods. Today's blog explores a novel technique that overcomes these limitations. Slide-Tag achieves high-throughput, single-nucleus barcoding with micrometer-scale spatial resolution and is compatible with various single-cell omics techniques. Read more: https://lnkd.in/dnmktd7w #SpatialTranscriptome #multiomics #singlecell #omics

𝗔𝗰𝗰𝗲𝘀𝘀 𝘁𝗼 𝘁𝗵𝗲 𝗹𝗮𝘁𝗲𝘀𝘁 #𝘀𝗶𝗻𝗴𝗹𝗲𝗰𝗲𝗹𝗹 𝗮𝗻𝗱 #𝘀𝗽𝗮𝘁𝗶𝗮𝗹𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 At the Earlham Institute, our single-cell and spatial analysis platform is open for service and collaboration with the bioscience community. We have some highly skilled biologists using the latest technology platforms to gain greater cellular insight, including: 📷 The BD S8 Discover - a cutting-edge spectral imaging #cellsorter, combining #spectralflow cytometry with real-time #spatial and morphological insights. *️⃣ The Vizgen Merscope - enabling the visualisation and mapping of hundreds to tens of thousands of RNA species, with the capability to quantify and map the #transcriptome of whole tissues down to a sub-cellular level. If you are starting with tissue, sorted cells or even pre-made libraries, we have the platforms and expertise to support your project. https://okt.to/SF9uhM #singlecellgenomics #singlecell #spatialanalysis #genomics #datascience #sequencing

The Human Cell Atlas (HCA) has arrived! 🧬 A groundbreaking collaboration in biotechnology involving 3,600 researchers from 102 countries, the HCA has released its first draft—a detailed map of human biology built cell by cell, tissue by tissue, organ by organ. With data from 62 million cells across all stages of human development, this elaborate resource is powered by cutting-edge technologies like single-cell RNA sequencing and AI tools from Google, ensuring inclusivity and global representation. The HCA offers immense potential for precision medicine, disease modeling, safer drugs, and AI-driven discoveries. The future of biotech just got a whole lot brighter! https://lnkd.in/eCNeb7-Y #HumanCellAtlas #Biotechnology #PrecisionMedicine #AI #Innovation #HCA #TechBio

I see a very promising future for liquid biopsy and mutli-omics: A Conversation with Morghan Lucas The Festival of Genomics and Biodata is just around the corner, and we’ve had the opportunity to sit down with ... The post “I see a very promising future for liquid biopsy and mutli-omics”: A Conversation with Morghan Lucas appeared first on Front ... https://lnkd.in/e-snAmjH #BioTech #science

Have you got questions about hashtag #singlecell or hashtag #spatialomics? The latest report from Front Line Genomics is the most comprehensive yet, pulling together the latest research and the intelligence of experts in the field.

Today, we're sharing an interesting watch with you! In case you missed the live version of our #webinar, 𝙐𝙣𝙡𝙤𝙘𝙠𝙞𝙣𝙜 𝙩𝙝𝙚 𝙨𝙥𝙖𝙩𝙞𝙖𝙡 𝙙𝙞𝙢𝙚𝙣𝙨𝙞𝙤𝙣: 𝙈𝙖𝙭𝙞𝙢𝙞𝙯𝙞𝙣𝙜 𝙞𝙣𝙨𝙞𝙜𝙝𝙩𝙨 𝙛𝙧𝙤𝙢 𝙨𝙥𝙖𝙩𝙞𝙖𝙡 𝙤𝙢𝙞𝙘𝙨 𝙙𝙖𝙩𝙖... 🍀 You're in luck! You can watch the recording in our knowledge hub ▶ https://lnkd.in/eDwKNp_3 In this webinar, Louise Leijonancker of Pixelgen Technologies and Viacheslav Mylka & Volodimir Olexiouk from BioLizard delve into the cutting-edge realm of spatial #omics technologies, to: 🌟 Guide you through how #spatial omics can deepen your biological understanding by preserving spatial context within molecular analyses, 🌟 Present an introduction to the pioneering molecular pixelation method for single cell spatial #proteomics, and 🌟 Share insights into #analysis of spatial omics data and integration of different omics data types, drawing on real-life #casestudies #spatialbiology #dataanalysis #lifescience #biotech #multiomics #spatialproteomics #spatialtranscriptomics

In case you missed it! neofleX, our new benchtop axial TOF/TOF, which benefits from fast analysis speed and flexibility in applications. Drive your ability for translational context with simultaneous imaging of >100 targeted proteins. Dig deeper into the multiomics molecular expression profiles for broad spatial contextualization. https://lnkd.in/eCraGzJu #massspectrometry #imaging #maldiimaging