Brenda Nelson-Porter, Neutral, ND, DM, PhD(c)’s Post

COULD TARGETING GENETICS REDUCE OUR CRAVINGS FOR SUGARY FOODS? A new study has revealed how genetic variations in the SI gene, which affects sucrose digestion, influence dietary preferences and intake of sugary foods. Researchers found that individuals with limited sucrose-digesting ability, due to specific genetic variations, showed reduced sugar cravings and consumption. This discovery opens up the potential to develop targeted treatments to reduce sugar intake on a population level, potentially reducing the incidence of obesity and type 2 diabetes. In studies, both mice and humans with impaired SI function consumed less sugar-rich foods, suggesting a natural link between sucrose tolerance and preference. Key Facts: 1. People with partial or total SI gene defects showed lower sucrose intake and preference. 2. Lower sucrose tolerance in the gut could reduce cravings for sugary foods naturally. 3. Targeting SI may offer new treatments for reducing sugar intake on a population scale. Source: https://lnkd.in/gujRrDNv

Effect of dietary glycerol monolaurate supplementation on gene expression, intestinal mucosa and microbiota of juvenile black sea bream (Acanthopagrus schlegelii). https://lnkd.in/eHUQiGN2

Non-Sugar Sweetener Consumption Alters Duodenal Microbial Diversity and Metabolic Pathways: REIMAGINE Study #Mysummary In this study conducted at Cedars-Sinai, researchers analyzed duodenal and stool samples from individuals consuming non-aspartame non-sugar sweeteners (NANS, n= 35), aspartame (ASP, n=9), and controls (n= 55). The findings reveal that NANS consumption is associated with decreased microbial diversity in the duodenum, where nutrient absorption happens. Interestingly, the relative abundance of potentially harmful bacteria like E. coli, Klebsiella, and Salmonella was lower in the duodenum of both NANS and ASP consumers compared to controls, suggesting a potential beneficial effect. Is this an artifact?! The circulating levels of the pro-inflammatory cytokine IL-1β were decreased in NANS consumers compared to controls, suggesting alterations in immune responses. The cylindrospermopsin biosynthesis pathway, which is linked to potential liver toxicity, was enriched in ASP consumers, raising concerns given the recent classification of aspartame as a possible carcinogen. #Mythoughts I wish the authors had used metagenomics instead of 16S sequencing - we could have had a better view of the changes in the gut microbiota composition. More studies with a larger number of volunteers are needed but it should not prevent us from taking action and already reducing the consumption of any type of sweeteners. HAPPY to hear your THOUGHTS and stay POSITIVE! #Myinspiration "We did not come to fear the future. We came here to shape it." Barack Obama Link to the paper here: https://lnkd.in/ecUkBCwH #microbiome #microbiology #science #biology #nature #health #pharma #probiotics #nutrition #diet #nature

Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice. https://lnkd.in/dctwa3TF

Dr. Robert Lufkin discusses the surprising reasons why grains can be harmful to your health. From gluten sensitivity to low-grade inflammation and exposure to harmful pesticides like glyphosate, this video exposes the potential risks of consuming grains. Stay informed and make healthier choices for your well-being. Clip from this podcast conversation: https://lnkd.in/gc_3hPZe #Health #Diet #Disease #Medicine #Food #Metabolism #Science #Biology #Podcast #Grains #Gluten #Glyphosate #Inflammation #Pesticides

🌾 New Low GI & High Protein Rice Discovered!🍚 IRRI researchers have developed rice varieties with ultra-low glycemic index (below 45%) and high protein content (15.99%), using advanced genetics and AI. This innovation could help control diabetes and improve nutrition in regions where rice is a staple. #HealthInnovation #LowGI #HighProteinRice #DiabetesPrevention #IRRI https://lnkd.in/gk7j_tE7

I'm excited to share our latest publication in Aquaculture Reports! Our study explores the effects of incorporating α-lipoic acid (LA) into a high-fat diet on lipid metabolism and mitochondrial function in Lateolabrax maculatus. We observed that LA significantly reduced lipid droplet accumulation and adipocyte size, which were notably larger in the high-fat diet group. Moreover, LA alleviated oxidative stress and enhanced mitochondrial function, as seen through increased enzyme activities. Additionally, LA promoted mitochondrial biogenesis and upregulated autophagy-related genes. Check out the full article for more details! 

📃Scientific paper: Nutrient availability of roughages in isocaloric and isonitrogenous diets alters the bacterial networks in the whole gastrointestinal tract of Hu sheep Abstract: Background The nutrient availability of roughages could affect the dietary utilization efficiency of ruminants even in isocaloric and isonitrogenous diets. Here, we analyzed the bacterial composition and their metabolic pathways in the gastrointestinal tracts (GITs) of Hu sheep fed with wheat straw (WS) instead of alfalfa (AL) in isocaloric and isonitrogenous diets, trying to explore the reasons from the perspective of GITs bacterial network structure changes. Results We employed 16S rRNA gene sequencing in combination with the Kruskal–Wallis test, Spearman correlation analysis, and other statistical methods to describe the microbiota composition in the GITs of Hu sheep. The results showed after the roughage was replaced from AL to WS, the most positive response occurred in the rumen microbiota, resulting in a more obvious microbiological and functional redundancy phenomenon. Whereas extended biogeographic studies of the GITs bacterial community found opposite results for the hindgut microbiota and metabolism networks compared to the forestomach. The abundance of fiber-degrading bacteria such as Prevotella , Oscillospiraceae NK4A214 group , and Treponema was significantly increased in GITs, but low-efficiency crude fiber degradation inhibited energy use efficiency, the pentose phosphate pathway, gluconeogenesis, and volatile acid synthesis. In addition, dietary shifting from AL to WS decreased the abundance of beneficial bacteria such as the Lachnospiraceae NK3A20 gro... Continued on ES/IODE ➡️ https://etcse.fr/5TeS ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

📃Scientific paper: Nutrient availability of roughages in isocaloric and isonitrogenous diets alters the bacterial networks in the whole gastrointestinal tract of Hu sheep Abstract: Background The nutrient availability of roughages could affect the dietary utilization efficiency of ruminants even in isocaloric and isonitrogenous diets. Here, we analyzed the bacterial composition and their metabolic pathways in the gastrointestinal tracts (GITs) of Hu sheep fed with wheat straw (WS) instead of alfalfa (AL) in isocaloric and isonitrogenous diets, trying to explore the reasons from the perspective of GITs bacterial network structure changes. Results We employed 16S rRNA gene sequencing in combination with the Kruskal–Wallis test, Spearman correlation analysis, and other statistical methods to describe the microbiota composition in the GITs of Hu sheep. The results showed after the roughage was replaced from AL to WS, the most positive response occurred in the rumen microbiota, resulting in a more obvious microbiological and functional redundancy phenomenon. Whereas extended biogeographic studies of the GITs bacterial community found opposite results for the hindgut microbiota and metabolism networks compared to the forestomach. The abundance of fiber-degrading bacteria such as Prevotella , Oscillospiraceae NK4A214 group , and Treponema was significantly increased in GITs, but low-efficiency crude fiber degradation inhibited energy use efficiency, the pentose phosphate pathway, gluconeogenesis, and volatile acid synthesis. In addition, dietary shifting from AL to WS decreased the abundance of beneficial bacteria such as the Lachnospiraceae NK3A20 gro... Continued on ES/IODE ➡️ https://etcse.fr/5TeS ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

🐄🌾 The transition period in dairy cows, from dry-off through postpartum, is critical for their health and productivity. Major dietary changes impact rumen function, health and the cow’s overall well-being. Calving significantly influences digestion, with studies showing changes in rumen wall histology and gene expression. Support your herd by monitoring: - Feedbunk and water trough space, - Stocking density of the fresh cow pen, - Adjust the ration for proper moisture, energy density and particle length, - Feed a live yeast probiotic like S. cerevisiae CNCM I-1077 (LEVUCELL SC) to help support rumen function and improved cow performance Learn more practical transition cow management and nutrition tips here: https://bit.ly/3VI7Wbc