About time! CONSENSUS STUDY REPORT A New Vision for Women's Health Research: Transformative Change at the National Institutes of Health - link at bottom Women make up over half of the U.S. population, yet research on women’s health conditions, including those that are female specific such as fibroids, more common among women such as anxiety, or affect women differently such cardiovascular disease, is severely lacking. Medical advances for women have lagged, in part due to a lack of understanding of basic sex-based differences in physiology. To address this, the National Institutes of Health’s (NIH) Office of Research in Women’s Health tasked the National Academies with convening a committee of experts to assess the state of women’s health research at NIH, identify critical knowledge gaps, assess the level of funding for women’s health research, and more. The resulting report outlines specific recommendations for NIH women’s health research priorities; training and education efforts to build, support, and maintain a robust women’s health research workforce; improving internal structures, systems and processes; soliciting, reviewing, and supporting women’s health research; and ensuring appropriate levels of funding. https://lnkd.in/eHVaJQEN
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For the better part of the past year, I have had the honor of co-chairing a NASEM study committee charged with assessing women’s health research at the NIH. I have had the privilege of working with and learning from a remarkable committee and staff. This report, A New Vision for Women's Health Research, Transformative Change at the National Institutes of Health, finds that while the NIH has made important contributions in women’s health research, there has been a persistent underinvestment in women’s health research and as result there are still many gaps. The committee is recommending a greater investment and a new women’s health research structure for NIH including: · A new Institute for women’s health, on female physiology and chromosomal differences, reproductive life course, and female-specific conditions not under purview of other ICs · A new fund to foster interdisciplinary and sex differences research · New and enhanced approaches to grow, support, and retain the women’s health workforce · Increased funding to support these efforts. We make recommendations for priority areas across the research continuum, with the goal of sparking breakthroughs to either prevent, treat, or reduce the amount of time women live with painful or debilitating conditions, as well as conditions that cause early mortality, such as cardiovascular disease, female-specific cancers, and maternal morbidity and mortality. The persistent lack of investments and resultant gaps have consequences on women’s lives, their families, and society as a whole. The committee concludes that if no change is made, slow and stagnant progress will continue to undermine the health and wellbeing of women and girls in this country. Sheila Burke; Sherita Golden; Robert Kaplan; Angeles Alvarez Secord; Neelum T. Aggarwal, MD; Chloe Bird, PhD, FAAAS, FAAHBHolly Ingraham; Nancy Lane; Jane Salmon; Crystal Schiller; Methodius Tuuli, MD, MPH, MBA; Bianca Wilson; Felina Cordova-Marks; Amy Geller
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Super honored to have been a part of the committee on the assessment of NIH research and women's health. Here is the recently released important report put out by The National Academies of Sciences, Engineering, and Medicine ! https://lnkd.in/gq4qU8bG "To advance health for AIAN women, it is essential to understand the history of colonialism and how it continues to reverberate through all aspects of health at systems, community, and individual levels. The effects of colonialism have created modern health inequities through violence, targeted eradication of AIAN people, erasure of culture, dispossession of land, removal from tribal homelands, forced urbanization, and more (Brown-Rice, 2013; Carroll et al., 2022; Moss, 2019; NASEM, 2023b). These health inequities exist, but it is important that solutions be framed to include community assets and viewed in terms of attaining balance among the components necessary for health and well-being in alignment with an Indigenous model of health.... (Greer and Lemacks, 2024; National Library of Medicine, n.d.)."
A New Vision for Women's Health Research
nap.nationalacademies.org
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An important report just announced from the NAP: A New Vision for Women's Health Research: Transformative Change at the National Institutes of Health (2025). I was particularly excited to see (page 36, second paragraph) "To expand and leverage data collection and analysis related to women’s health, NIH is launching an effort to standardize these data..." Those of us, in informatics research, practice, and policy are critical to this agenda and poised to move forward. Great things to come in 2025! #womenshealthresearch #womenshealth #womenshealthdatainitiative #datastandards https://lnkd.in/gP8pUnnW
A New Vision for Women's Health Research
nap.nationalacademies.org
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In research, it seems like the work never stops, even during Summer. But sometimes we do finish something 😉 Last week, our review on socioeconomic position and frailty has been published in Ageing Research Reviews. In this review, led by Peter Hanlon and co-authored by several EPI-FRAIL colleagues, we included 383 studies reporting findings from 265 samples/cohorts. No matter what SEP indicator was used (childhood deprivation, education, income, occupation etc.), lower SEP was associated with higher frailty prevalence, frailty incidence and frailty progression. Resourcing of interventions and services to support people living with frailty should be proportionate to needs in the population to avoid widening existing health inequalities. See for more information: https://lnkd.in/dFz6QJrg More information about EPI-FRAIL: www.epi-frail.com Amsterdam UMC, Amsterdam Public Health, Amsterdam Cohort Hub - Amsterdam UMC, University of Glasgow, Karolinska Institutet
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let's briefly review the translational research phases: T1 (Translation to Humans): This phase involves applying basic science discoveries to clinical studies, typically in controlled settings. It's focused on understanding mechanisms and developing new treatments or interventions. T2 (Translation to Patients): This phase is about testing the efficacy and safety of these interventions in controlled environments, often through clinical trials. It aims to establish the clinical benefits and optimize the interventions. T3 (Translation to Practice): This phase is concerned with implementing and disseminating the findings from T1 and T2 in broader clinical practice. It focuses on how well these interventions work in real-world settings and identifies barriers to implementation. T4 (Translation to Population Health): This phase extends the findings to a broader population, aiming to affect public health policy and practice at large.
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Women make up over half of the U.S. population, yet research on women’s health conditions, including those that are female specific, more common among women, or affect women differently, is severely lacking. To address this, the National Academies convened a committee of experts, that included UNC Health psychologist Dr. Crystal Schiller, to assess the state of women’s health research at NIH, identify critical knowledge gaps and the allocation of funding needed to address them, provide recommendations on NIH structure, policies, and programs to optimize women’s health, and more. https://lnkd.in/eVdJEtrg
A New Vision for Women's Health Research: Transformative Change at the National Institutes of Health
nap.nationalacademies.org
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In her new Forefront article, Michal Elovitz from the Icahn School of Medicine at Mount Sinai discusses how for too long, there has been a failure to invest resources and efforts focused on female and sex-specific biology. As a result, we do not currently understand the basic biology that drives many conditions that burden women. "Women comprise more than half of the population. Yet, women’s health research is understudied and underfunded. Women and their doctors need more information to understand diseases that impact them; they need more tools to help identify who is at risk for adverse health outcomes; and they need more therapeutics to prevent or treat the many conditions that continue to unduly burden women." Read the full article here: https://bit.ly/440wujb
The Urgent Need To Advance Women’s Health Research | Health Affairs Forefront
healthaffairs.org
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Yet another phenomenal step in the right direction toward improving our understanding of all facets of #womenshealth. We simply cannot progress far in #personalizedmedicine or #precisionmedicine without these fundamental underpinnings first.
NIH has launched a Notice of Special Interest to elevate #WomensHealth research as part of The White House Initiative on Women’s Health Research. Learn about the initiative & how it aims to drive innovation in this field of research: https://bit.ly/3QlNnzs #WomensHealthMonth #WomensHealth #WomensHealthResearch #research #science #NIH
Notice of Special Interest (NOSI): Women’s Health Research
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"For far too long, scientific and biomedical research excluded women and undervalued the study of women’s health. The resulting research gaps mean that we know far too little about women’s health across women’s lifespans, and those gaps are even more prominent for women of color, older women, and women with disabilities." - EO on Advancing Women’s Health Research and Innovation (3/18/24) Within this context, President Biden is issuing an executive order "to bolster women's health research, while federal agencies are announcing new steps to close long-standing gender gaps in clinical trials and care." - Axios WH EO fact sheet: https://lnkd.in/eRJm8Fm6 Executive Order: https://lnkd.in/eiVT6f9w Axios: https://lnkd.in/eUC5vjXY
FACT SHEET: President Biden Issues Executive Order and Announces New Actions to Advance Women’s Health Research and Innovation | The White House
whitehouse.gov
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