European Association for Cancer Research (EACR)’s Post

Highlights in Cancer Research 💡 Discover the paper 'Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment': https://lnkd.in/gk3a8_aT

The EACR Board has selected the latest highlights in recent cancer research papers. Discover why they chose the Cancer Discovery paper 'Cancer Mutations Converge on a Collection of Protein Assemblies to Predict Resistance to Replication Stress': https://lnkd.in/ek2gNri4

Slightly outside of the current GenAI & Machine Vision spotlight, researchers here have used an unsupervised single hidden layer NN model to determine there are two distinct types of prostate cancer, formed by two different evolutionary trajectories. Shared below from PharmaTimes https://lnkd.in/eF5RqA6A, their paper is also published in full here https://lnkd.in/epgSNxFu

▪ UC San Diego Researchers Develop Innovative Therapy for Liver Cancer Researchers at UC San Diego have made significant progress in targeting hepatocellular carcinoma (HCC), a highly resistant form of liver cancer. They have engineered stem cell-derived natural killer (NK) cells that effectively combat HCC by disabling a protein that hinders immune function. Unlike personalized treatments like CAR T-cell therapy, this NK-cell therapy can be mass-produced and made shelf-ready, enabling immediate patient intervention. Lead researcher Dr. Dan Kaufman highlights the therapy's potential to enhance anti-tumor activity and improve survival rates, currently below 20% for HCC. This groundbreaking research may lead to clinical trials and new effective treatments for solid tumors, marking a major advancement in cancer therapy. Read more: https://lnkd.in/g_NpxPat

Cancer cells hijack essential vitalizing processes from their environmental cells and remember their learnings. We have shown that "the acquired characteristics" of glioma cancer cells also have electrical and synaptic activity like neurons, even in isolation. Our paper is here:https://lnkd.in/guZjApNN Eric Topol, MD article in the Ground Truth on this subject is here: https://lnkd.in/gK3r7SJv

Check out this case study on how we are using iPSC-neurons to study tumour-nerve interactions in panceratic cancer. https://lnkd.in/esfh_ZSY

Scientists at New York University have created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. The model, published in the journal Life Science Alliance, allows researchers to study a process previously hidden from view and may open the door to new screening and treatment options for cancers at risk of spreading. More from the NYU News Release below 📰 https://hubs.la/Q02VHSw40 Read the original paper published in Life Science Alliance🔬 https://hubs.la/Q02VHSmK0

Exploring the mysteries of aging, unraveling its connection to cancer, and envisioning the future of oncology—these were just a few topics covered in this recent interview. http://bit.ly/4aV0DCG

NCI ARTNet a program supported by the Division of Cancer Biology and NCI Division of Cancer Treatment and Diagnosis, focuses on the mechanisms of acquired resistance to #CancerTherapies and disease recurrence. https://lnkd.in/eBcw6zVe

🚨 In a groundbreaking development in cancer research, Cancer Research UK,Cell Genomics @CellGenomics, has unveiled a pivotal study that challenges the notion of prostate cancer as a singular disease. Utilizing the power of artificial intelligence, researchers have delved deep into the intricate complexities of prostate cancer, revealing a spectrum of variations that demand personalized approaches to treatment. This significant breakthrough marks a paradigm shift in our understanding of the disease, offering new insights into its diverse manifestations and paving the way for tailored treatment strategies. This revelation underscores the importance of harnessing cutting-edge technology to decode the intricacies of cancer biology and develop targeted interventions that address the unique characteristics of each patient's cancer. By recognizing that prostate cancer is not a uniform entity but rather a spectrum of distinct subtypes, researchers are poised to revolutionize how we approach diagnosis, prognosis, and treatment decisions. However, amidst this groundbreaking discovery, it's crucial not to overlook the critical role of early detection. Men, heed the call: prioritize regular check-ups and screenings. Early detection remains our most potent weapon in the fight against prostate cancer, offering the best chance for successful treatment outcomes and improved survival rates. Let's unite in the battle against cancer and ensure that every individual receives the care and support they need to thrive. @NDSurgicalSci, Nuffield Department of Surgical Sciences at the University of Oxford https://buff.ly/3T2Mkoi