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Here are the main points from the article: Triazenolysis: A new chemical process called triazenolysis has been introduced, which transforms alkenes into multifunctional amines. These amines have potential applications in polymers, pharmaceuticals, and agriculture. Comparison with Ozonolysis: Unlike the century-old ozonolysis that forms carbon-oxygen bonds, triazenolysis efficiently creates carbon-nitrogen bonds, making it more versatile for various scientific and industrial fields. Research Team: The process was developed by researchers at the Schulich Faculty of Chemistry at the Technion, including doctoral students Alexander Koronatov and Deepak Ranolia, postdoctoral researcher Pavel Sakharov, and Prof. Mark Gandelman. Publication: The study was published in Nature Chemistry and supported by the Israel Science Foundation. This breakthrough could significantly impact the production of raw materials for various industries. Fascinating, isn't it? https://lnkd.in/g9KFY-H6

#CHEMISTRY: 𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗶𝗻 𝗘𝗻𝘇𝘆𝗺𝗲 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗳𝗼𝗿 𝗚𝗿𝗲𝗲𝗻 𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆🔬 Researchers Dr. Xiao-Dan Li, Dr. Richard Kammerer, and Prof. Dr. Volodymyr Korkhov at the PSI Paul Scherrer Institut have successfully characterized the enzyme styrene oxide isomerase for the first time.🚀🔬 Published in Nature Chemistry, this breakthrough paves the way for environmentally friendly production of valuable chemicals and drug precursors. By elucidating the enzyme's structure and function, the team has overcome previous limitations to its practical application.🌱 Using advanced techniques like cryo-electron microscopy, the researchers uncovered that the enzyme's efficiency owes to an iron-containing group, similar to the iron-containing pigment in our blood. This allows the enzyme to split the epoxide ring in styrene oxide, a key step in the Meinwald reaction, with high precision, producing only one specific product.🎯 Their findings promise significant advances for the chemical and pharmaceutical industries, offering a versatile, energy-saving tool for green chemistry.🌐💊 👉 Learn more >> https://lnkd.in/guMZm_jp #BioChemistry #GreenChemistry #EnzymeResearch #SustainableScience #EnvironmentalScience Science-Switzerland Follow the Consulate of Switzerland, Swissnex in Japan🇨🇭🇯🇵 #AddingValue | #Education | #Research | #Innovation | #Startups🚀 | #VitalitySwiss

#Chemistry | 𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗶𝗻 𝗘𝗻𝘇𝘆𝗺𝗲 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗳𝗼𝗿 𝗚𝗿𝗲𝗲𝗻 𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆 | Researchers Dr. Xiao-Dan Li, Dr. Richard Kammerer, and Prof. Dr. Volodymyr Korkhov at the PSI Paul Scherrer Institut have successfully characterized the enzyme styrene oxide isomerase for the first time. Published in Nature Chemistry, this breakthrough paves the way for environmentally friendly production of valuable chemicals and drug precursors. By elucidating the enzyme's structure and function, the team has overcome previous limitations to its practical application. Using advanced techniques like cryo-electron microscopy, the researchers uncovered that the enzyme's efficiency owes to an iron-containing group, similar to the iron-containing pigment in our blood. This allows the enzyme to split the epoxide ring in styrene oxide, a key step in the Meinwald reaction, with high precision, producing only one specific product. Their findings promise significant advances for the chemical and pharmaceutical industries, offering a versatile, energy-saving tool for green chemistry. 👉 Learn more >> https://lnkd.in/guMZm_jp 🇨🇭 Follow #ScienceSwitzerland for trending updates on Swiss scientific, technological, educational, and innovative advancements >> www.swissinnovation.org Follow us >> Science-Switzerland #Science | #Education | #Research | #Innovation

Cryo-EM data collection and processing All the cryo-EM datasets of SOI were collected using EPU software on a 300-kV Titan Krios system (Thermo Fisher Scientific ) equipped with a Gatan K3 direct electron detector and a Gatan Quantum-LS GIF, at ScopeM, ETH Zurich. All movies were acquired in super-resolution mode with a defocus range of −0.5 to −3 μm and were binned twofold after acquisition in EPU.

Låkril scientists Benjamin Hoekstra and Lyle Monson have developed a novel GC method to aid in the development of the Låkril Amber Technology for the production of bio-based acrylics. This dual-column stopped-flow method quantifies permanent gases, organic acids and water from a single injection, yielding more complete compound identification and mass balance data in complex process streams. Analysis of permanent gases and organic acids is typically performed with separate methods due to challenges in achieving sufficient resolution while using column stationary phases which are chemically compatible with acids. We developed an online analysis method to continuously analyze samples containing high levels of water, organic acids (lactic acid, acrylic acid), oxygenates, and permanent gases (CO, CO2, C2H4) using a single injection. Ben Hoekstra recently introduced this method to the public at the Fall ACS meetings in Denver, and a detailed paper has just been published in Analytical Chemistry. Read more here: https://lnkd.in/g4T4YhQq

At the link below is our now in ASAP paper at Analytical Chemistry on a dual-column #gaschromatography method for determination of organic acids and permanent gases

𝗔 𝗯𝗶𝗼𝗻𝗮𝗻𝗼𝗺𝗮𝗰𝗵𝗶𝗻𝗲 𝗳𝗼𝗿 𝗴𝗿𝗲𝗲𝗻 𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆: Researchers at the Paul Scherrer Institute PSI have for the first time precisely characterised the enzyme styrene oxide isomerase, which can be used to produce valuable chemicals and drug precursors in an environmentally friendly manner. The study appears in the journal Nature Chemistry. Enzymes are powerful biomolecules that can be used to produce many substances at ambient conditions. They enable “green” chemistry, which reduces environmental pollution resulting from processes used in synthetic chemistry. One such tool from nature has now been characterised in detail by PSI researchers: the enzyme styrene oxide isomerase. It is the biological version of the Meinwald reaction, an important chemical reaction in organic chemistry. 𝗪𝗶𝘁𝗵 𝘁𝗵𝗲 𝗵𝗲𝗹𝗽 𝗼𝗳 𝗮𝗻 𝗲𝗻𝘇𝘆𝗺𝗲, 𝘁𝗵𝗲 𝗶𝗻𝗱𝘂𝘀𝘁𝗿𝘆 𝗰𝗼𝘂𝗹𝗱 𝗽𝗿𝗼𝗱𝘂𝗰𝗲 𝘃𝗮𝗹𝘂𝗮𝗯𝗹𝗲 𝗰𝗵𝗲𝗺𝗶𝗰𝗮𝗹𝘀 𝗮𝗻𝗱 𝗱𝗿𝘂𝗴 𝗽𝗿𝗲𝗰𝘂𝗿𝘀𝗼𝗿𝘀 𝗶𝗻 𝗮𝗻 𝗲𝗻𝗲𝗿𝗴𝘆-𝘀𝗮𝘃𝗶𝗻𝗴 𝗮𝗻𝗱 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁𝗮𝗹𝗹𝘆 𝗳𝗿𝗶𝗲𝗻𝗱𝗹𝘆 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀: https://lnkd.in/eAwFvtFv Xiao-Dan Li, Richard Kammerer, Zhi Xian Li, Volodymyr Korkhov

I am excited to share an experience from my undergraduate research. It was a highly rewarding time focused on the green synthesis of nanoparticles. Green synthesis is an eco-friendly method of producing nanoparticles using plant extracts, bacteria, algae and fungi, which is important for reducing environmental impact. Green synthesized nanoparticles can be safely used in agriculture, pharmaceutical, cosmetic, food and beverage industries. For my research, I used neem leaves (Azadirachta indica) to synthesize ZnO, MgO, and sulfur nanoparticles. Neem leaves play a crucial role in green synthesis due to their natural reducing and stabilizing properties. It felt like a magical process to see the formation of nanoparticles. The experience was incredibly amazing and taught me the potential of sustainable practices in scientific research. 🧑🔬 #greensynthesis #nanoparticles #ecofriendly #research

𝗕𝗿𝗲𝗮𝗸𝗶𝗻𝗴 𝗯𝗼𝗻𝗱𝘀 𝘁𝗼 𝗳𝗼𝗿𝗺 𝗯𝗼𝗻𝗱𝘀: #𝗥𝗲𝘁𝗵𝗶𝗻𝗸𝗶𝗻𝗴 𝘁𝗵𝗲 #𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆 𝗼𝗳 𝗖𝗮𝘁𝗶𝗼𝗻𝘀: A team of chemists from the University of Vienna, led by Nuno Maulide, has achieved a significant breakthrough in the field of chemical synthesis, developing a novel method for manipulating carbon-hydrogen bonds. This groundbreaking discovery provides new insights into the molecular interactions of positively charged carbon atoms. By selectively targeting a specific C–H bond, they open doors to synthetic pathways that were previously closed – with potential applications in medicine. The study was recently published in the journal Science. Living organisms, including humans, owe their complexity primarily to molecules consisting mainly of carbon, hydrogen, nitrogen, and oxygen. These building blocks form the basis of countless substances essential for daily life, including medications. When chemists embark on synthesizing a new drug, they manipulate molecules through a series of chemical reactions to create compounds with unique properties and structures. 𝗡𝗲𝘄 𝗰𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗿𝗲𝗮𝗰𝘁𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗺𝗲𝗱𝗶𝗰𝗶𝗻𝗮𝗹 𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆: https://lnkd.in/e7iMtsVw Universität Wien