INESC-ID’s Post

🌟 Exciting Research Highlight! 🌟 In the study "Irreversible light-activated SpyLigation mediates split-protein assembly in 4D" conducted by researchers from the University of Washington, Bioer LifeEco thermal cycler played a crucial role. Precise and advanced amplificaiton of DNA was essential for cloning LASL plasmids and synthesizing the photocaged amino acid for photoactivatable SpyCatcher (pSC). Published in Nature Communications, this research underscores the precision and reliability of the LifeEco thermal cycler in groundbreaking scientific endeavors. Read the full article and discover more about Bioer's thermal cycler and applications! https://lnkd.in/gnqUsbyx #Bioer #LifeEco #ThermalCycler #ScientificResearch #Biotechnology #PCR #Genetics #Innovation #4DAssembly #SpyLigation

🚀📢 𝐍𝐞𝐰 𝐏𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐀𝐥𝐞𝐫𝐭! We're thrilled to announce that our PacBio+Illumina hybrid assembly strategy has successfully produced a single, circularized contig for the 13.08-Mb genome of 𝘋𝘢𝘤𝘵𝘺𝘭𝘰𝘴𝘱𝘰𝘳𝘢𝘯𝘨𝘪𝘶𝘮 sp. This novel strain from the Sarawak forest can utilize natural or synthetic rubber as its sole carbon source. In collaboration with the Sarawak Biodiversity Centre, Universiti Sains Malaysia and Nagaoka University of Technology, we've discovered three novel and unique latex clearing protein (lcp) genes and their genetic organization. Expressing these genes in 𝘌𝘴𝘤𝘩𝘦𝘳𝘪𝘤𝘩𝘪𝘢 𝘤𝘰𝘭𝘪 showed varying degrees of degrading activity against natural rubber. The genomic information and validation from this research provide a valuable reference for future characterization and engineering work. We're excited about the potential applications and further explorations this opens up! 🌿🔬 #Research #Genomics #Biotechnology #SyntheticBiology #Collaboration #Innovation #Sustainability #PacBio #Illumina #RubberDegradation #Bioinformatics #CoGen #CodonGenomics #Biologicaldatacompany

🔬 Am excited to share my latest research findings on delving into the anti-inflammatory potential of Adansonia digitata stem bark extract has been an enlightening journey. My study sheds light on its impact on MCP-1 and VCAM-1 receptors, paving the way for potential therapeutic anti-inflammatory agents. 💡 Additionally, I'm passionate about understanding the normal mechanisms behind pro-inflammatory signals and their role in microbial defense. Join me in the quest to decipher these pathways and how they go awry at disease states. Let's connect and collaborate to advance scientific understanding! #Biochemist #ResearchEnthusiast #InflammationResearch #MicrobialDefense #ScientificDiscovery 🧪📚

Do you want to read about our recent paper in Nature Communications (Nature Portfolio)? Lindlich's one and only Jan Lukas Krüsemann brings it to the point nicely. The full article can be read at https://lnkd.in/dUzc3WDG

How can we use #AI to improve #biomanufacturing and #syntheticbiology? Watch our new short video about the deCYPher research project that is developing cutting-edge bioprocesses using microbes as cell factories. The deCYPher project aims to revolutionize industrial applications by integrating biological and data-driven techniques. A key focus is the creation and implementation of CYP proteins to enhance microbial cell factories.

💡 𝗪𝗵𝗮𝘁 𝗶𝗳 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀 𝗮𝗳𝗳𝗲𝗰𝘁𝗶𝗻𝗴 𝗽𝗿𝗼𝘁𝗲𝗶𝗻 𝘀𝘁𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗳𝗼𝗹𝗹𝗼𝘄𝗲𝗱 𝘀𝗶𝗺𝗽𝗹𝗲 𝗺𝗮𝘁𝗵𝗲𝗺𝗮𝘁𝗶𝗰𝗮𝗹 𝗿𝘂𝗹𝗲𝘀? 🧬 Researchers from the 𝘾𝙚𝙣𝙩𝙧𝙚 𝙛𝙤𝙧 𝙂𝙚𝙣𝙤𝙢𝙞𝙘 𝙍𝙚𝙜𝙪𝙡𝙖𝙩𝙞𝙤𝙣 (#CRG) and the 𝙒𝙚𝙡𝙡𝙘𝙤𝙢𝙚 𝙎𝙖𝙣𝙜𝙚𝙧 𝙄𝙣𝙨𝙩𝙞𝙩𝙪𝙩𝙚 have discovered that mutations affecting protein stability follow remarkably simple mathematical rules. This groundbreaking study, published in #Nature, 𝐫̲𝐞̲𝐯̲𝐞̲𝐚̲𝐥̲𝐬̲ ̲𝐭̲𝐡̲𝐚̲𝐭̲ ̲𝐭̲𝐡̲𝐞̲ ̲𝐠̲𝐞̲𝐧̲𝐞̲𝐭̲𝐢̲𝐜̲ ̲𝐚̲𝐫̲𝐜̲𝐡̲𝐢̲𝐭̲𝐞̲𝐜̲𝐭̲𝐮̲𝐫̲𝐞̲ ̲𝐨̲𝐟̲ ̲𝐩̲𝐫̲𝐨̲𝐭̲𝐞̲𝐢̲𝐧̲𝐬̲ ̲𝐢̲𝐬̲ ̲𝐬̲𝐢̲𝐦̲𝐩̲𝐥̲𝐞̲𝐫̲ ̲𝐭̲𝐡̲𝐚̲𝐧̲ ̲𝐩̲𝐫̲𝐞̲𝐯̲𝐢̲𝐨̲𝐮̲𝐬̲𝐥̲𝐲̲ ̲𝐭̲𝐡̲𝐨̲𝐮̲𝐠̲𝐡̲𝐭̲, allowing for accurate genetic predictions in high-dimensional sequence spaces. 🌟 This discovery has profound implications for accelerating the development of new treatments for diseases and designing new proteins for industrial applications. 🌐🔬 📖 Read more about this fascinating research here: https://lnkd.in/gDRYabjd #science #bioinformatics #research #genomics #ProteinStability #Innovation

If you’re attending the AGBT - Advances in Genome Biology and Technology meeting, be sure to check out our poster. John Vieceli our SVP of Product Development will be presenting – BEYOND THE GENOME: UNRAVLEING PROTEIN VARIABLITY WITH QUANTUM-SI’S NEXT GENERATION PROTEIN SEQUENCING™ TECHNOLOGY.  Next-generation protein sequencing is a transformational tool to unlock new insights into the function of proteins in health and diseases. Quantum-Si’s Platinum® technology brings the insights of protein sequencing to every lab with a space-friendly benchtop instrument, a simple end-to-end workflow, and single-molecule resolution that enables detection of protein variants and modifications. Poster #531. Join the presentation today 430-6:10pm ET. And click here to learn more about the power of #Platinum®: https://lnkd.in/ekwUJc-5 #AGBT2024 #QuantumSi #QSI #proteomics #proteinsequencing #proteinsequencing #ngps #innovation #technology #research #health #biotech 

📣 Introducing our host, Dr Nisha Lakhotia, Account Manager, AGRF. On Thursday 29 August at La Trobe University, Dr Lakhotia will host this insightful workshop, Emerging Technologies - Genomics and Proteomics. 🔉 In this workshop, Dr Lakhotia will 🔎 explore the topic: "Beyond Short Reads: Revealing Niche Differences with Full-Length 16S and ITS Long-Reads for Enhanced Understanding of Microbial Diversity."   🤝 Join us as Dr Lakhotia delves into how full-length 16S and ITS long-read sequencing, facilitated by PacBio HiFi technology, can uncover niche differences between closely-related strains. This advanced approach enables a more comprehensive understanding of microbial communities by providing detailed Alpha and Beta diversity measures, ASV classification, taxonomic classification, and comprehensive phylogenetic and diversity metrics.   🛰 Discover how this methodology enhances our exploration of microbial communities, offering valuable insights into their structure and ecological roles. This workshop promises to be an enlightening experience, offering practical knowledge and cutting-edge techniques for advancing our understanding of microbial diversity.   ❗ Don't miss this opportunity to gain a deeper appreciation of the complexities within microbial ecosystems with one of the leading experts in the field. 📆 For event registration and details follow this link: https://lnkd.in/gaCnxT2h #AGRF #Genomics #Proteomics #Olink #Research #Bioscience #Biochemistry #Medicalresearch #PacBio #microbialdiversity

GreenGate Genomics is ready for the spring, are you? 🌱 ☀ Do you want to find out how our expertise and know-how can support your next research journey? Visit our website www.greengategenomics.com, we have made some allaround changes to better showcase what we stand for and how we can help researchers and scientists with their projects. ◼ Interested in talking to us? Use our contact form to reach out! ◼ Take a look at our resources page to find some useful tips on genomic data analysis and processing. ◼ Want to leave feedback? With our new feedback form you can do just that! ◼ Prefer 🇩🇪 ? Our website is available in both English and German now! Whether you're a researcher at an academic institution, a government agency, or a biotech company, we would be happy to discuss your specific bioinformatic and genomic needs and we are happy to answer any questions! #Bioinformatics #SpringProjects #Innovation #Research #Genomics #Biotechnology

Always looking to get better at what we do. Take advantage of our new features to let us know how we can best support microbial genomics users! 💹 #TuesdayMotivation #StartUp #Bioinformatics #MicrobialGenomics