🌾 Exciting Research Update! 🐄🐑 I’m happy to share that two abstracts from our latest research were presented at the 2024 ASAS Annual Meeting and have been published in the Journal of Animal Science. These studies bring us closer to enhancing fertility outcomes and bolstering offspring immunity against infectious diseases. 📚 Read more here: 1.Characterizing the seminal microbiota in mature rams managed on divergent planes of nutrition, and in their male offspring Fusobacterium Study https://lnkd.in/giVj6qtR 2.Screening and isolation of Fusobacterium necrophorum and Fusobacterium varium from seminal, and vagino-uterine microbiota of healthy cattle and sheep Seminal Microbiota in Rams Study https://lnkd.in/gacxWDZG My constant gratitude goes to my advisor Dr Amat, coauthors and NDSU Microbiological Sciences and Biotechnology for this interesting journey of knowing how much I don't know. #AnimalScience #Microbiome #ReproductiveHealth #LivestockResearch
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We have been discussing using algae-based diets for fish 🐟 and much research has been done about their effects on growth and immunology. But did you know that studying their effects on fish reproduction is also important? Here 👇 you have our latest article on this 🔥 topic and a hint about the potential usage of algae for fish broodstock feeds! Centre of Marine Sciences (CCMAR) | Aquaculture Research Group (Aquagroup) | @Bioskel
Effects of dietary supplementation with macroalgae on sperm quality and antioxidant system in Senegalese sole
sciencedirect.com
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📣📣 We are thrilled to announce the #publication of our latest #research paper titled: "Dietary Administration of #Bacillus_subtilis Improves #Health Parameters and Regulates #Gene Expression in #Mice Receiving #Zearalenone-Contaminated Diet." 🔆 This study, conducted at the #Arka Industrial and Mineral Research Center, has been published in the *Brazilian Journal of Microbiology*, which boasts an impact factor of 2.1. Our research aims to combat #Zearalenone and other #fungal toxins by leveraging the power of #bacteria that decompose these harmful substances. Zearalenone, a significant non-polar #mycotoxin, mimics #estrogen and can adversely affect the #reproductive and #immune systems when absorbed into the bloodstream. This poses serious challenges for the reproductive health of #cattle and #poultry and #aquatic animals. In our study, we evaluated the potential of *Bacillus subtilis* in mitigating the effects of Zearalenone. Here’s how it works: 🔆 Key Mechanisms of Bacillus subtilis Against Zearalenone: 1. #Degradation: #Bacillus subtilis breaks down Zearalenone in the #digestive_system. 2. Binding: The bacterium binds Zearalenone to its cell wall, preventing its absorption into the #bloodstream. 3. Cellular Uptake: Bacillus subtilis absorbs Zearalenone into its cells, further reducing its #bioavailability. 4. #Detoxification: The bacterium produces #enzymes that decompose Zearalenone into less toxic compounds. 5. Immune Support: Bacillus subtilis enhances #immune function and #liver health by promoting probiotic growth in the gut. Conclusion: To combat non-polar mycotoxins like Zearalenone, incorporating toxin binders containing #microorganisms or enzymes that degrade these toxins is essential. Relying solely on #bentonite is insufficient for effective removal of such #toxins. 🔔 For more information, feel free to reach out! Dr. Ehsan Oskoueian Industrial and Mineral Research Center Arka Industrial Cluster #ArkaIndustrialCluster #FeedAdditives #Nutrition #FungalToxins #Poultry #Mycotoxin #Veterinary #AnimalScience #Feed #Livestock #toxinbinder #mycotoxin #mycotoxins #zearalenone #toxins #biodetoxification #probiotics #probiotic #animalnutrition
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Addressing Johne’s disease is essential, with efforts centered on managing Mycobacterium avium subsp. paratuberculosis (MAP) by treating infected cattle and curbing its spread. Phage therapy emerges as a promising strategy for controlling MAP infections. This research developed a library of MAP-specific lytic phages to evaluate their therapeutic value under conditions simulating those in infected cattle, such as ruminal fluid, milk, and the bovine gut epithelium. The phage library demonstrates strong lytic activity against MAP, with some also targeting other harmful mycobacterial species. Laboratory tests reveal that certain phages retain stability and effectiveness in complex biological environments and can inhibit MAP colonization in bovine epithelial cells, suggesting potential preventative use in livestock. This phage library could be transformed into probiotic-like products for economical Johne’s disease control. #PhageTherapy #AnimalHealth https://buff.ly/48nsknT
Discovery of Mycobacterium avium subsp. paratuberculosis Lytic Phages with Extensive Host Range Across Rapid- and Slow-Growing Pathogenic Mycobacterial Species
mdpi.com
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Today marked two week of significant milestone as I defended my project titled "Hematological Changes and In Response in Animals with Imbalanced Gut Microbiota Treated with Lactobacillus Species." This research journey has been nothing short of enlightening, and I’m thrilled to share this moment captured in the photo above! 🚀 The Journey: From the outset, my goal was to uncover the intricate relationship between gut microbiota and systemic inflammation. The imbalanced gut microbiota has been linked to various health issues, making it crucial to explore therapeutic interventions. My focus was on Lactobacillus species for their potential to restore balance and promote health. 🔍 Key Findings: My research revealed that the administration of Lactobacillus species resulted in significant hematological changes, reducing inflammation markers and enhancing the overall health of the studied animals. These findings could pave the way for future studies in gut health and its systemic effects. 🤝 Gratitude: This achievement wouldn’t have been possible without the guidance of my advisors and the support of my peers. I extend my heartfelt thanks to everyone involved in this journey. Your encouragement fueled my passion for discovery! 📈 Looking Ahead: I am excited to continue this line of inquiry, and I hope that my findings contribute to meaningful advancements in the fields of microbiome research and veterinary health. It’s inspiring to think about the potential impacts our work can have on both animal and human health. Here’s to embracing challenges, pursuing knowledge, and contributing to the ever-evolving landscape of science! 🧬💪 #ResearchDefense #Lactobacillus #GutMicrobiota #Hematology #Inflammation #VeterinaryScience #Microbiome #ScientificResearch #Gratitude #HealthAndWellness
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Check out this fascinating article discussing the potential of gene-editing in bolstering immunity against prevalent diseases like PRRS! 🧬🔬 #Genetics #Healthcare #Research https://lnkd.in/grjfa896
Gene-edited pigs show resistance to PRRS
agriculture.com
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Check out our new research article showing the analysis of blood transcriptome of cattle during bovine tuberculosis. Our study highlights the dynamic transcriptomic changes during bovine tuberculosis, particularly highlighting the involvement of lncRNAs with immune-related genes. The identified immune pathways and gene–lncRNA interactions offer valuable insights for further research in understanding host–pathogen interactions and potential avenues for genetic improvement strategies in cattle. For further details, check out our article https://lnkd.in/gw8482fx
In-silico analysis of cattle blood transcriptome to identify lncRNAs and their role during bovine tuberculosis - Scientific Reports
nature.com
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RT: Plant Pathology @BSPPjournals 🍻 🇨🇦#OpenAccess GWAS of adult plant resistance to spot blotch in an elite Canadian two-row barley germplasm collection: Genome-wide association study of adult plant resistance to spot blotch in an elite Canadian two-row barley germplasm collection James R. Tucker, Ana Badea, W. G. Dilantha Fernando, Colin W. Hiebert, Alexander C. Woitas, Aaron D. Beattie First published: 04 April 2024 https://lnkd.in/drjr4m9n #barley #germplasm #genebank #spotblotch #resistance #geneticresources #plantbreeding #prebreeding #beer ... Abstract Spot blotch, caused by Bipolaris sorokiniana, is a growing concern for barley (Hordeum vulgare) production in most humid, temperate growing regions of the world. Under epidemic conditions, this disease can reduce yields significantly. Reduction of kernel plumpness is associated with lower malt extract and consequently grain quality. Enhanced resistance to this disease is a major goal of western Canadian two-row barley breeding programmes; however, two-row barley is considered to be more susceptible than six-row barley. Plant–pathogen interactions observed for Canadian germplasm are polygenic, where quantitative breeding methods could be beneficial for the development of resistant germplasm. A germplasm panel consisting of 200 two-row, spring barley genotypes with differential reaction to spot blotch was evaluated at Brandon, Manitoba (MB), and Melfort, Saskatchewan (SK), over eight site years. Genome-wide association study was conducted using a 50k single-nucleotide polymorphism (SNP) Illumina iSelect genotyping array. The most-resistant germplasm was found to carry Midwest Six-rowed Durable Resistant Haplotype (MSDRH) alleles at the loci located on chromosomes 1H (Rcs-qtl-1H-11_10764), 3H (Rcs-qtl-3H-11_10565) and 7H (Rcs-qtl-7H-11_20162, Rcs5 locus), where the 3H locus was found to be the most under-represented in Canadian germplasm. Additional marker-trait associations within nurseries were identified on chromosomes 1H, 2H and 4H. Several of the SNP markers identified were found to be polymorphic within the Canadian two-row germplasm panel and thus could be useful for enhancing spot blotch resistance in two-row barley for development of resistant cultivars.
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In our latest article we explore the complicated landscape of Early Blight-causing pathogens on potato, which ones are truly pathogenic under our test conditions, and how some of them interact (or not) https://lnkd.in/e9-Giuet #potato #plantpathology #alternaria #EarlyBlight #phytopathology #potatopathogens #potatocrop
Pathogenicity of Single and Combined Inoculations of Alternaria spp. on Potato - Potato Research
link.springer.com
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CHINA - Huazhong Agricultural University: Amur Barberry (Berberis Amurensis) inhibits #ASFV proliferation by interfering with early viral infection stages. Luteolin, found in common vegetables like broccoli, has demonstrated the ability to suppress the virus's replication cycle by modulating key signaling pathways. Researchers from Huazhong Agricultural University, in collaboration with the Hubei Jiangxia Laboratory, have published a comprehensive review (DOI: 10.1186/s44149-024-00122-1) in the journal Animal Diseases. The study delves into the advancements of Traditional Chinese Medicine (TCM) in the prevention and control of ASF, highlighting the #antiviral and #immunoregulatory capabilities of herbal compounds. The comprehensive review meticulously details the multifaceted approach of TCM in addressing ASF. It underscores the antiviral potential of various herbal extracts, such as berbamine hydrochloride from Berberis amurensis Rupr., which inhibits ASFV proliferation by interfering with early viral infection stages. Luteolin, found in common vegetables like broccoli, has demonstrated the ability to suppress t he virus's replication cycle by modulating key signaling pathways. The study also highlights the role of TCM in immunomodulation, showcasing how certain herbal formulas can enhance the pigs' immune responses and potentially reduce the severity of ASF. The integration of such traditional knowledge with modern scientific methods presents a robust strategy to combat this devastating disease, illustrating the profound impact of TCM in contemporary veterinary medicine. Dr. Qiang Zhang, a corresponding author and expert in veterinary medicine, emphasizes the importance of this research, stating, "TCM offers a unique perspective in managing diseases like ASF. Its multi-component, multi-target approach can potentially lead to more effective and safer treatments with less risk of resistance development." The findings suggest that integrating TCM into modern pig farming practices could significantly bolster disease prevention and control measures. The use of herbal additives in feed and the development of TCM-based antiviral drugs present promising avenues. Moreover, this research could pave the way for a deeper understanding of TCM mechanisms, facilitating its integration with Western medicine and contributing to global health strategies against ASF and potentially other infectious diseases. https://lnkd.in/d7v6JQYa #swine #swineindustry #feedadditives #herbalextracts #porkmarket #asf #stopspreadasf #africanswinefever
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