Lift Up: Women in Life Sciences’ Post

Dr. Ronald Klatz, MD, DO Worldhealth.net MIT #researchers have developed implantable #microparticles that deliver two #cancer therapies - #phototherapy and #chemotherapy - simultaneously. This approach targets aggressive #tumors more effectively and may reduce side effects associated with traditional intravenous chemotherapy. In mouse studies, this dual therapy led to complete tumor elimination in most subjects and significantly extended their survival. #worldhealth #cancertherapy #medicine #regenerativemedicine #clinicalresearch #medtech #health #wellness https://lnkd.in/guGQH3sd

Researchers give new insight into role of PTPRK in tissue repair, cancer Using human colorectal cancer cell lines, the team found that the deletion of PTPRK altered the appearance of the cells, compared to control cells where PTPRK was functional, and observed that the knockout cells showed impaired wound-healing response, which was likely to be due to the loss of PTPRK affecting coordinated action by cells and their neighbours and defects in cellular polarisation. #Researchers | #Tissuerepair | #Colorectal | #Cancercell | #Appearance | #Controlcells | #Functional | #Woundhealing | #Knockoutcells | #Coordinated | #Cellular | #Polarisation | #Healthnews Read more:

#IDIBELL and Institut Català d'Oncologia (ICO) researchers show that the colon cancer liver #metastases growth pattern may influence the response to #immunotherapy via the tumor microenvironment composition. These results, published in #MedComm, could have a major impact on the personalisation of treatments. https://lnkd.in/dKh-DGgQ

https://lnkd.in/dyiMGZqB Tumor/#stromal expression of #CD3/CD8/PD-1/PD-L1 and overall survival (OS) in patients (pts) with #metastatic (met) #HER2+ #breast cancer (BC)

🔥 Breakthrough for head and neck cancer treatment! 💡A new CT-based clinical-radiomics model significantly enhances 5-year progression predictions, outperforming traditional TNM8 staging. 🌟 AUC: 0.74 | Risk stratification made simpler with SHAP explainability. 🚀 #CancerResearch #Radiomics  Read here: https://lnkd.in/d-6NPe8C INCLIVA Instituto de Investigación Sanitaria Quibim Gema Bruixola Núria Grimalt Ferrer

#SpeakingofScience: In a recent breakthrough, Stanford University School of Medicine unveiled #AI-powered tools that offer new hope for treating soft tissue #sarcomas, a rare and challenging #cancer. The study mapped out distinct cellular configurations within these tumors, revealing insights into patient outcomes and #cancertreatment responses. One key finding is the identification of a cellular neighborhood linked to a positive response to #immunotherapy, potentially revolutionizing treatment approaches. Despite the cancer's complexity, #machinelearning techniques helped unravel crucial insights into the tumor microenvironment. This study challenges previous assumptions by suggesting that tumors with an intermediate level of immune cell infiltration may respond best to immunotherapy. Dr. Moding's team aims to validate these findings further, with the support of collaborative efforts and funding agencies. 🔬🚀 #CancerResearch #AI #Immunotherapy #PrecisionMedicine #StanfordMedicine #ClinicalResearch #Biotech #AIinhealthcare #MedTech #HealthcareInnovation #CancerDiscovery

Our Leeds - Manchester study of 228 patients with non-metastatic anal cancer, just published in Springer Nature British Journal of Cancer, demonstrates that MR derived extra-mural vascular invasion and tumour signal heterogeneity are novel prognostic biomarkers for loco-regional failure - HR 2.70 [95% CI1.39–5.24] and HR 2.66 [95% CI 1.29–5.48] respectively in addition to mrTumour (HR: 1.43 per cm [95% CI: 1.26–1.63]) and mr Nodal status (HR 2.70 [95% CI1.39–5.24]. University of Leeds Leeds Teaching Hospitals NHS Trust The University of Manchester #analcacner #radiotherapy #biomarkers #patients

Research sheds light on the role of PTPRK in tissue repair and cancer

At the Johns Hopkins Kimmel Cancer Center Prostate Multidisciplinary Clinic, patients receive personalized care from a team of experts and cutting-edge treatments. Among these is HDR prostate brachytherapy, a specialized therapy offered at only a few centers nationwide. This advanced approach precisely targets the #prostate, minimizing radiation to surrounding tissues for enhanced safety and efficacy. #ProstateCancer #Multidisciplinary https://bit.ly/3ZMDCz8

Researchers at Samsung Medical Center and Ulsan National Institute of Science and Technology have advanced our understanding of pancreatic ductal adenocarcinoma (PDAC) using cutting-edge scRNA-seq analysis. By examining both primary tumors and metastatic lesions, they've uncovered critical insights into cancer subtypes and their impacts on patient outcomes. #pancreaticcancer #medicalbreakthrough https://lnkd.in/gC9pcH9r