Manchester Cancer Research Centre’s Post

What are the key take aways from #BTOG24? Here, Drs Gerry Hanna and Fiona McDonald provide significant updates in radiotherapy. They discuss the findings of the most recent The Royal College of Radiologists audit data – looking at radiotherapy quality and numbers. They also discuss a study comparing radiotherapy in oncogene addicted lung cancer vs non-oncogene addicted. Watch here & stay tuned for other updates. The Royal Marsden NHS Foundation Trust Trinity College Dublin BRITISH THORACIC ONCOLOGY GROUP (BTOG) #Research #lungcancer #radiotherapy #PatientAdvocacy

Dose constraints in breast cancer radiotherapy. A critical review Out on the Green Journal Radiotherapy has become increasingly important in the treatment of breast cancer, particularly for patients with locoregional disease who are now experiencing long-term survival. Advances in radiotherapy techniques, such as intensity-modulated radiotherapy (IMRT), volumetric-modulated arc therapy (VMAT), and deep inspiration breath-hold (DIBH), along with the adoption of hypofractionated schedules and partial breast radiotherapy for selected patients, have transformed treatment approaches. These innovations necessitate new dose-volume constraints (DVCs) for organs at risk (OARs) in various treatment settings. This review examines the current evidence on DVCs for whole breast/chest wall radiotherapy, regional nodal irradiation, and partial breast irradiation to help standardize treatment planning. Fiorenza De Rose Maria Carmen De Santis  Sara Lucidi Riccardo Ray Colciago Francesca Cucciarelli  Eliana La Rocca  Francesca D.  Frank Lohr  Valentina Vanoni  Bruno Meduri #BreastCancer https://lnkd.in/dH5NaAw9

Review examines the current evidence on DVCs for whole breast/chest wall radiotherapy, regional nodal irradiation, and partial breast irradiation to help standardize treatment planning. #BreastCancer

We are thrilled to announce the winners of the CT or CBCT Guided Online Adaptive Radiotherapy Clinical Case Reports publishing competition! After receiving submissions from around the world covering a wide span of clinical applications, we are excited to share the top three case reports as determined by the Cureus community’s SIQ ratings on article importance and quality. Read the articles: https://hubs.la/Q02StKTb0 🥇 1st Place - 7.42 SIQ Solution for the External Contour Changes in Cone Beam Computed Tomography-Guided On-demand Online Adaptive Radiotherapy for a Patient With Very Advanced Head and Neck Cancer: A Technical Case Report 🥈 2nd Place - 6.69 SIQ Online Adaptive Radiotherapy for Planning Target Volume (PTV) Reduction in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma 🥉 3rd Place - 6.33 SIQ Cone-Beam Computed Tomography-Guided Online Adaptive Radiotherapy: Promising Results for Bladder Cancer Case Sponsored by Varian

✨Congrats @VincentVinhHung ✅Which metric is the most representative of the doses to OAR's to be free of model-assumption, non-parametric to avoid the temptation to fit parameters, blind to knowledge of response? ✅ A retrospective group of patients treated with the same hypofractionation schedule of 42 Gy to the breast and integrated tumor bed boost in 15 fractions. Nicolas BENZIANE-OUARITINI Sarah Belhomme Tahiti Infos Institut Bergonié SFRO - Société Française de Radiothérapie Oncologique SFjRO-Société Française des Jeunes Radiothérapeutes Oncologues Amethyst Radiothérapie France Amethyst Radiotherapy Group Breast Cancer Care Breast Cancer Academy #breast #cancer #radiotherapy https://lnkd.in/eNHcY8XX

Radiotherapy could hold the key for unlocking a significant advance in treating late-stage lung cancer. In a world-first, NHS teams at The Christie are carrying out the first trial in 20 years using radiotherapy to improve quality and length of life for lung cancer patients. And there are hopes that the treatment could even offer a cure. The Thoracic Umbrella Radiotherapy Study (TOURIST) is using new radiotherapy tools only previously used for people with early-stage cancer. This type of radiotherapy uses a rotating machine giving multiple beams of radiation at different strengths directly on the tumour; and is used alongside immunotherapy and/or chemotherapy. We keep saying it: radiotherapy is amazing. The sooner we can unleash its potential, the sooner we can #CatchUpWithCancer. Read more ➡️ https://bit.ly/3zIxDBo

The key to prevention of burdensome late radiation toxicities, and thus ensuring QoL after radiotherapy treatment, is accurate prediction of the risk for individuals. In this prospective study of patients irradiated for prostate or gynecologic cancer, we aimed to validate the γ-FDR as a predictive marker for late radiation toxicity. Do you want to read more? Please find our latest article entitled “Genetic markers of late radiation toxicity in the era of image-guided radiotherapy: lower toxicity rates reduce the predictive value of γ-H2AX foci decay ratio in patients undergoing pelvic radiotherapy” in BMC Cancer radiotherapy. Authors: Karin Nuijens, Arlene Leonie Oei, PhD, Lisa Koster, Ron Hoebe, KLaas Franken, Coen Rasch & Lukas Stalpers https://lnkd.in/g7-yXpbK

We are thrilled to announce the winners of the CT or CBCT Guided Online Adaptive Radiotherapy Clinical Case Reports publishing competition! After receiving submissions from around the world covering a wide span of clinical applications, we are excited to share the top three case reports as determined by the Cureus community’s SIQ ratings on article importance and quality. Read the articles: https://hubs.la/Q02StHPh0 🥇 1st Place - 7.42 SIQ Solution for the External Contour Changes in Cone Beam Computed Tomography-Guided On-demand Online Adaptive Radiotherapy for a Patient With Very Advanced Head and Neck Cancer: A Technical Case Report 🥈 2nd Place - 6.69 SIQ Online Adaptive Radiotherapy for Planning Target Volume (PTV) Reduction in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma 🥉 3rd Place - 6.33 SIQ Cone-Beam Computed Tomography-Guided Online Adaptive Radiotherapy: Promising Results for Bladder Cancer Case Sponsored by Varian

📢 Join us on June 20th for the next #AccurayExchange webinar, "Intensity Modulated Radiotherapy (IMRT) for Anal Squamous Cell Cancer" Learn more on the subject with Marianna Alessandra Gerardi & Raffaella Cambria, moderated by Barbara Jereczek-Fossa! #AccurayExpandRT https://lnkd.in/daw-VX6t

📘 New research published in Radiotherapy & Oncology is paving the way for breakthroughs in carbon-ion radiation therapy (CIRT)! A groundbreaking study has developed the first NTCP model to predict Grade ≥ 2 Acute Oral Mucositis (AOM) in patients with head and neck cancer. 🎓 By integrating dosimetry, radiomics, and dosiomics, the model achieves remarkable accuracy, offering a powerful tool for clinical decision-making. Discover the full details of this innovative study and its potential to reshape radiation oncology ➡️ https://bit.ly/4axDnMm #FRPT2024 #FRPT2025 #Radiotherapy #InnovationInOncology #RadOnc