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🔆 Engineering Photosynthetic Yeast!! 🍻 🔆🍻 Researchers have developed a method to convert heterotrophic organisms into autotrophic ones, enabling them to assimilate carbon from CO2. 🔆🍻 This is typically achieved through metabolic engineering, but in this study a "directed endosymbiosis" approach is employed to introduce photosynthetic capabilities into budding yeast. 🔆🍻 By engineering cyanobacterial endosymbionts to assimilate carbon and secrete sugars, the team created yeast/cyanobacteria chimeras capable of propagating under photosynthetic conditions without external carbon sources like glucose. 🔆🍻 The chimeras were engineered to produce natural products such as limonene under these conditions. 🔆🍻 This method was extended to standard yeast strains, allowing for more versatile applications in synthetic biology and biotechnology. 🔆🍻 The study highlights that combining yeast's genetic tractability with cyanobacteria's photosynthetic abilities can optimize CO2 conversion into useful chemicals. 🔆🍻 By leveraging cyanobacteria's glucose secretion and ATP production the yeast/cyanobacteria hybrids offer a new platform for biosynthesis under photosynthetic conditions. 🔆🍻 These findings could advance sustainable production of chemicals and provide insights into evolutionary processes such as organelle adaptation, endosymbiosis, and genome minimization. What do you think? 👍🏻 and 🔄 the knowledge :) Follow me for more! Dr. Hamed Altaweel

CARBON CAPTURE CONTD.... BIOENGINEERING SOLUTIONS FOR LONG TERM CO2 STORAGE Biotechnology advances carbon capture technologies by offering innovative solutions for making use of microorganisms and genetic engineering techniques to enhance carbon isolation. Some key aspects are: • Engineered Microbes: By engineering microorganisms, researchers can enhance their ability to capture and convert carbon dioxide into valuable products or store it more efficiently. • Carbon-neutral Biomaterials: can replace fossil fuel- derived products. For example, researchers are exploring the use of genetically modified microorganisms to produce bio-based plastics, chemicals and construction materials. • Synthetic Biology: researchers can create synthetic pathways that efficiently capture and convert carbon dioxide by combining genetic components from different organisms. • Genetic Engineering of Crops: by modifying genes involved in photosynthesis, carbon fixation, or root development, scientists aim to create crops that capture and store more carbon in their biomass and soil. 🙏🌍🙏

"Biotechnology Innovations: Towards Sustainable Health and a Secure Future" - ## Introduction: The Importance of Biotechnology in the Modern Era Biotechnology is one of the fundamental pillars supporting progress in many fields, from healthcare to agriculture and environmental protection. With the increase in chronic disease rates and environmental challenges, it has become essential to rely on innovative scientific solutions to ensure a healthy and sustainable future. Recent statistics indicate that the global biotechnology market may reach $727.1 billion by 2025, reflecting a growing trend in this field. The qualitative leaps in areas such as genomics, the development of biological drugs, and agricultural technologies illustrate the shift towards using technology to address contemporary challenges. In this context, the article seeks to explore the key innovations in biotechnology and how they can contribute to improving quality of life and achieving environmental sustainability.## Innovations in Healthcare Amid the rapid medical innovations, biotechnology is a cornerstone in the development of new treatments and drugs that target diseases more precisely. Techniques such as gene editing are among the most prominent advancements, utilizing tools like CRISPR to modify genes associated with genetic diseases. This allows for the correction of genetic defects before symptoms appear, contributing to a reduction in the incidence of both rare and common diseases. Moreover, biotechnology enables the development of immunotherapies, such as enhanced therapy, which works to bolster the immune system’s ability to combat cancer. By using genetically modified antibodies, scientists can improve the body’s response to tumors in ways that were previously unimaginable. This has transformed the landscape of cancer treatment, providing hope to many patients. ## Agricultural Applications of Biotechnology Biotechnology also significantly contributes to improving agricultural productivity by developing pest- and disease-resistant crops. By utilizing modern technologies such as genetic engineering, it is possible to create plant varieties that can withstand harsh climatic conditions and require less water and other agricultural resources. This positively affects food security amid a growing population and climate change. Additionally, biotechnology can be used to produce biostimulants that enhance plant growth and increase their ability to absorb nutrients. Thanks to these innovations, it is possible to reduce reliance on harmful chemicals, contributing to the health of the environment and biodiversity. ## Environmental Protection Biotechnology plays a pivotal role in environmental protection strategies by developing innovative solutions to address environmental problems. For example, genetically modified microbes are used to clean soil and water from toxic pollutants, aiding in the restoration of damaged ecosystems. This field is known as environmental ...

This month HALRIC reached a milestone with a total of 39 approved pilot projects, which has taken us more than halfway towards the goal of reaching 75 cross-border collaborations by 2026🎯🎉 Today we feature a pilot project, which contributes to optimizing time-resolved crystallography techniques at MAX IV Laboratory. The results could enhance our understanding of LPMO enzymes and lead to industrial applications in biofuels and new strategies for combating pathogens. The collaboration also builds on the Department of Chemistry, University of Copenhagen - UCPH's extensive knowledge and crystallographic studies of Lytic polysaccharide monooxygenases (LPMOs). The LPMO enzymes have a characteristic copper site being able to degrade recalcitrant polysaccharides, as well as additional implications in microbial pathogenesis of humans and important crop plants. Single crystal structure studies of microbial LPMOs at cryo-temperatures have been instrumental in elucidating their structure-function relationship, and have been the basis for mutagenesis, protein engineering and computational chemistry aimed at understanding the details of the reaction. Serial crystallography emerges as a promising technique to capture the dynamic process of LPMOs’ action in a time-resolved manner, as it can be carried out at room temperature, potentially providing a deeper understanding of their catalytic mechanism at the molecular level. This knowledge could lead to optimized industrial applications and innovative strategies in pathogen control. In order to use serial crystallography for a time-resolved study, the reaction must be triggered in a controlled manner, and the triggering mechanism is a specific focus of this pilot project collaboration between Leila Lo Leggio, Mohannad Aloula, Yusuf Theibich, Zhiyu Huang, Jie Nan, Monika Bjelcic. If this has inspired you to become a partner in a HALRIC pilot project, the next call for proposals ends on 28 November and you can find further info here: https://lnkd.in/dZANC__8

Great example of research on #LPMO enzymes, important for potential industrial applications in biofuels and for combating pathogens. #maxiv #ucph #HALRIC #crystallography #xrays #physics #biology #research

Exploring the Colorful World of Biotechnology: The Color code of Biotechnology Biotechnology is an exciting and diverse field that uses living organisms to create innovative solutions for various industries. To help you understand the different areas within biotechnology, scientists have categorized it into distinct "colors." Let's explore these vibrant sectors: 1. 🌿 Green Biotechnology Agriculture & Environment Green biotechnology focuses on improving agriculture. This includes genetically modified crops, biofertilizers, and biopesticides to enhance crop yields and reduce environmental impact. 2. 🧬 Red Biotechnology Healthcare & Medicine Red biotechnology is dedicated to medical advancements. It involves developing new drugs, vaccines, and therapies, including gene therapy and stem cell treatments. 3. 🌊 Blue Biotechnology Marine & Aquatic Applications Blue biotechnology utilizes marine organisms to create products like pharmaceuticals, enzymes, and biofuels. It plays a crucial role in discovering new drugs and sustainable ocean resources. 4. ⚗️ White Biotechnology Industrial Processes White biotechnology applies biological methods to industrial processes. It uses enzymes and microorganisms to produce chemicals, materials, and bioenergy sustainably. 5. 🟣 Purple Biotechnology Bioinformatics & Nanotechnology Purple biotechnology combines bioinformatics and nanotechnology. It involves using computational tools to analyze biological data and developing nanoscale devices for diagnostics and treatments. 6.🧪 Yellow Biotechnology Food Production & Nutrition Yellow biotechnology focuses on improving food safety and nutrition. It includes developing functional foods with added health benefits and dietary supplements. 7.🚀 Grey Biotechnology Environmental Applications Grey biotechnology is all about environmental protection. It includes bioremediation, using microorganisms to clean up pollution, and sustainable waste management practices. 8. 🟡 Gold Biotechnology Bioinformatics & Computational Biology Gold biotechnology, also known as bioinformatics, involves the use of computational tools to manage and analyze biological data. It is essential for advancements in genomics, proteomics, and understanding complex biological systems. 9. ⚫ Black Biotechnology Bioterrorism & Biosecurity Black biotechnology deals with bioterrorism and biosecurity. It involves the study and prevention of the misuse of biological research and technology for harmful purposes. Learn More About Biotech! Curious to learn more about these colorful branches of biotechnology? Head over to our YouTube channel for in-depth videos and stay updated with the latest innovations and trends in the field. Don't miss out on our engaging and educational content! 🔗 Watch Now on YouTube https://lnkd.in/gqRrDNc8 #Biotechnology #GreenBiotech #RedBiotech #BlueBiotech #WhiteBiotech #PurpleBiotech #YellowBiotech #GreyBiotech #drjyotibala #STEM #Innovation

Alcaligenes Genus Overview: Alcaligenes is a genus of Gram-negative, aerobic bacteria commonly found in water and soil environments. Medical Relevance: Some species, like Alcaligenes faecalis, can be opportunistic pathogens, particularly in immunocompromised individuals. Industrial Applications: These bacteria are used in biotechnology for the production of enzymes and bioremediation of pollutants. Unique Characteristics: Alcaligenes species are known for their ability to thrive in alkaline environments and can degrade a variety of organic compounds. Antibiotic Resistance: They exhibit resistance to many common antibiotics, making infections challenging to treat.

Cyclodextrins a "super molecules" Cyclodextrins are cyclic oligosaccharides composed of glucose units linked by α-1,4-glycosidic bonds. Their structure forms a toroidal or doughnut-shaped molecule with: Hydrophobic interior: This allows them to encapsulate non-polar molecules. Hydrophilic exterior: This makes them soluble in water. The most common types are: α-Cyclodextrin: Six glucose units. β-Cyclodextrin: Seven glucose units. γ-Cyclodextrin: Eight glucose units. Why It's a "Super Molecule" Encapsulation Capability: Cyclodextrins can form inclusion complexes by trapping guest molecules in their hydrophobic cavity. This property is used for stabilizing, solubilizing, and protecting various compounds. Environmental Friendliness: They are biodegradable, non-toxic, and derived from starch, making them an eco-friendly option in various industries. Versatility in Applications: Pharmaceuticals: Enhance drug solubility, stability, and bioavailability. Food Industry: Mask unpleasant tastes or odors and stabilize flavors. Cosmetics: Stabilize active ingredients and improve delivery. Environmental Science: Remove organic pollutants from water through encapsulation. Chemical Modifications: Cyclodextrins can be chemically modified (e.g., methylation, hydroxypropylation) to tailor their properties for specific applications. Self-Assembly: Cyclodextrins can act as building blocks for supramolecular assemblies, enabling the creation of nanomaterials, sensors, and drug delivery systems. Scientific and Industrial Impact Cyclodextrins exemplify the principles of supramolecular chemistry, where molecular recognition and host-guest interactions are key. Their use has revolutionized several fields, demonstrating the power of molecular engineering. If you'd like to explore specific applications or dive deeper into their chemistry, contact to CarboHyde

Synthetic biology (SynBio) is reshaping the future—merging biotechnology, molecular biology, engineering, biophysics, and much more, to tackle global challenges like climate change, health, and food security. Curious how these transformative technologies are making an impact today? 🔗 Dive into this thought-provoking conversation featuring Dr. Orly Savion , PhD, CEO of Alagene Ltd., and Alon Turkaspa, Climate & Agrifood Tech Lead at Startup Nation Central 👉https://okt.to/LOVJZi Israel’s unique innovation ecosystem is strengthened by a bold entrepreneurial spirit, cross-disciplinary collaboration, and solid academia-industry ties, and this is driving SynBio breakthroughs that deliver actionable solutions across sectors. Neta Agmon, Hylabs, Dotan Buchsweiler, Ilanit Burnstein, Yahalom, Aviv Bresler, Tamir Tuller iGEM Competition Phytolon Imagindairy Aleph Farms EcoPhage BiomX Inc Scala Bio MNDL Bio CollPlant