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CD spectroscopy is a powerful tool for studying the secondary structure of proteins, it provides valuable insights into their conformational changes, stability, and interactions.  With our instrumentation and expertise, we offer precise and reliable analysis tailored to meet your specific needs. Whether you're developing new biologics or assessing formulation stability, our CD spectroscopy services can provide the critical data you need to drive your biopharmaceutical research forward. 𝗦𝗲𝗿𝘃𝗶𝗰𝗲𝘀 𝘄𝗲 𝗢𝗳𝗳𝗲𝗿: •Protein Secondary Structure Analysis: Determine protein structural elements.  •Conformational Changes: Monitor protein conformational alterations.  •Protein Stability Assessment: Evaluate stability under different conditions.  •Comparative Analysis: Compare structural properties of proteins.  •Quality Control: Ensure consistency and integrity of products.  •Thermal & Chemical Stability: Assess stability parameters.  Biophysical Characterization: Offer insights into biomolecule structure. Connect with us to discuss how our CD services can propel your research or biopharmaceutical development to new heights! . Write to projects@zellebiotech.com to know more about how Zelle Research & Analytical services can help you overcome such challenges . #ProteinStability #proteinstructure #CDAnalysis #Biopharmaceuticals #AnalyticalServices #ScienceInnovation #protein #monitoring #circulardichoism #regulatoryrequirement #analysis #connections #services #analyticalchemistry #lab #molecules #stabilitystudies #research #zellebiotech #ZRAS 

Interesting read in BioProcess International as AGC Biologics sought a path to single use in downstream processing, demonstrating Protein A membrane chromatography coupled to membrane polishing was able to achieve: ·     10x higher productivity than resin ·     effective impurity removal ·     ability to supply drug-substance manufacturing capability https://lnkd.in/eMcRU-VZ #GoreProteinCapture #antibodypurification #membranechromatography

📢 Revolutionary Guidelines Transform Biologics Screening Process! 🧪 U.S. researchers set new guidelines for 96-well plate chromatography experiments. 🔬 Developed by the University of Virginia, these standards aim to enhance consistency and quality in biologics screening. 📈 The goal is to help companies achieve reliable results across departments, aiding comparison in the industry. 💻 A supportive software package is released for experimental design, applicable to various protein-based products. #BioprocessUpdates #BiologicsScreening #PlateBasedBiologics #Chromatography #ResearchInnovation #UVA #QualityStandards #LifeSciences #ProteinResearch #LaboratoryTech #ExperimentalDesign #Biotech #ResearchCommunity #ConsistentResults #ScientificGuidelines #Biopharmaceuticals ▷ Read the full article here: 📎 https://lnkd.in/dpbsnE8V

The PyroGene® rFC Assay is the evolution of the traditional LAL test. Combining 21st century technology with the horseshoe crab’s endotoxin-sensitive Factor C protein, Lonza developed an equivalent, reliable and sustainable endotoxin detection method. This research paper 👇 from Korea provides more information on reliability and validation of the rFC assay and how it can be applicable in the biopharmaceutical industry. Want to learn more about rFC? Article: 👉 https://lnkd.in/eAarQdCn Product page: 👉 https://lnkd.in/dyAP48M #rFC #endotoxin

𝗘𝗻𝗵𝗮𝗻𝗰𝗶𝗻𝗴 𝗔𝗻𝘁𝗶𝗯𝗼𝗱𝘆 𝗣𝘂𝗿𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗘𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝘆 𝘄𝗶𝘁𝗵 𝗣𝗿𝗲𝗰𝗶𝘀𝗶𝗼𝗻 𝗮𝗻𝗱 𝗥𝗲𝗹𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗗𝗼𝘄𝗻𝗹𝗼𝗮𝗱 𝗣𝗗𝗙 𝗦𝗮𝗺𝗽𝗹𝗲 𝗖𝗼𝗽𝘆: https://bit.ly/3ziciy2 The global protein A resin market in terms of revenue was estimated to be worth $1.2 billion in 2022 and is poised to reach $2.1 billion by 2028, growing at a CAGR of 9.8% from 2022 to 2028 The new research study consists of an industry trend analysis of the market. A specialized type of chromatographic medium used extensively in the biopharmaceutical industry for the purification of antibodies, particularly monoclonal antibodies (mAbs). The resin is composed of a solid support matrix (often agarose or synthetic polymers) to which Protein A, a bacterial protein that binds specifically to the Fc region of antibodies, is immobilized. This affinity binding allows for the selective capture and subsequent purification of antibodies from complex mixtures, making Protein A chromatography a highly efficient and reliable method in downstream processing. 𝗕𝘆 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 Research Pharmaceuticals 𝗕𝘆 𝗰𝗼𝗺𝗽𝗮𝗻𝘆 Merck Tosoh Bioscience, Inc. GE HealthCare Biogen Thermo Fisher Scientific #ProteinA #Chromatography #AntibodyPurification #Biopharmaceuticals #MonoclonalAntibodies #AffinityChromatography #Biotech #DownstreamProcessing #PurificationTechnology #Bioprocessing #TosohBioscience #GEHealthcare #ThermoFisherScientific #RA #researchallied Research Allied

Biopharmaceutical Process Analytical Technology Market worth $2.6 billion by 2029 Download PDF Brochure@ https://lnkd.in/dZD2PAzs The report "Biopharmaceutical Process Analytical Technology Market by Technology (LC, GC, MS, qPCR, NGS, NMR, Raman, IR Spectroscopy), Product (Analyzer, Sensor, Software), Application (Vaccine, Biologics, CGT), and End User - Global Forecast to 2029", is projected to reach USD 2.6 billion by 2029 from USD 1.2 billion in 2024, at a CAGR of 16.0% during the forecast period. The global embrace of #Process #AnalyticalTechnologies (PAT) is propelled by heightened research investment from #biopharmaceutical firms, rigorous regulatory criteria for drug safety, improvements in #drugquality, and technological advancements. Companies Profiled in This Report: Waters Corporation Thermo Fisher Scientific Danaher Corporation Agilent Technologies SHIMADZU CORPORATION Bruker Emerson ABB PerkinElmer Mettler-Toledo International, Inc ZEISS Group

Biopharmaceutical Process Analytical Technology Market worth $2.6 billion by 2029 📚 𝐃𝐨𝐧'𝐭 𝐦𝐢𝐬𝐬 𝐨𝐮𝐭! 𝐆𝐫𝐚𝐛 𝐒𝐚𝐦𝐩𝐥𝐞 𝐂𝐨𝐩𝐲 𝐨𝐟 𝐑𝐞𝐩𝐨𝐫𝐭:- https://lnkd.in/dbWch476 Biopharmaceutical Process Analytical Technology market in terms of revenue was estimated to be worth $1.2 billion in 2024 and is poised to reach $2.6 billion by 2029, growing at a CAGR of 16.0% from 2024 to 2029 The report "Biopharmaceutical Process Analytical Technology Market by Technology (LC, GC, MS, qPCR, NGS, NMR, Raman, IR Spectroscopy), Product (Analyzer, Sensor, Software), Application (Vaccine, Biologics, CGT), and End User - Global Forecast to 2029" 𝐓𝐡𝐞 𝐜𝐨𝐦𝐩𝐚𝐧𝐢𝐞𝐬 𝐭𝐡𝐚𝐭 𝐚𝐫𝐞 𝐨𝐩𝐞𝐫𝐚𝐭𝐢𝐧𝐠 𝐢𝐧 𝐭𝐡𝐢𝐬 𝐦𝐚𝐫𝐤𝐞𝐭 𝐠𝐥𝐨𝐛𝐚𝐥𝐥𝐲 Thermo Fisher Scientific, Danaher Corporation, Agilent Technologies, SHIMADZU CORPORATION , Waters Corporation , Bruker , Emerson, Abbott , PerkinElmer, Mettler-Toledo International, Inc, and Carl Zeiss do Brasil Ltda.

Advancing Biosimilar Development: Precision Meets Innovation In biosimilar development, ensuring product quality requires analytical methods that are as rigorous as they are versatile. Our recent work, published in Analytical Biochemistry, highlights a breakthrough: the validation of an LC-HRMS peptide mapping method using NISTmab as a model. Key Highlights: ✅ Achieved unmatched accuracy and precision in identifying critical quality attributes (CQAs). ✅ Demonstrated robustness across varied conditions, ensuring reliability. ✅ Validated a platform that supports multi-product biosimilar development. This method is a step forward in streamlining therapeutic protein analysis, offering the biopharmaceutical industry a cost-effective and scalable solution. How do you see analytical innovations shaping the future of biosimilar development? I’d love to hear your insights! #Biosimilars #Innovation #AnalyticalMethods #BiopharmaLeadership

Join this webinar to hear how A-TEEM spectroscopy bridges the gaps in sensitivity and selectivity left by other analytical tools. #biopharma #mAB #proteins #cellmedia #proteintherapeutics

Small Molecules vs Biologics in Pharma 💊🧬 Small Molecules ⚗️ - Small molecules are simple chemical compounds with low molecular mass. Due to their small size, they can easily penetrate cells and reach intracellular targets, and can often be administered orally and topically. - Advantages : *Easier production and quality control. *Can often be administered orally and topically. *Affordable generics are widely available. - Disadvantages: *Less specific, with risks of off-target effects. *More likely to have drug-drug interactions. Biologics 💉 - Biologics are much larger and more complex molecules, derived from living organisms (peptides, enzymes, antibodies ...). However, they often must be administered via injection or infusion and require more complex production processes. Advantages: *High specificity, reducing the risk of off-target effects. *Effective for difficult to treat diseases. Disadvantages: *Higher production costs. *Increased risk of immune reactions. *Stricter storage conditions required. If you’d like to learn more about these two approaches, feel free to comment and share this post ! 👇 📩 #Chemistry #Pharma #Biologics #SmallMolecules #Innovation #DrugDevelopment