We are excited to announce that Aparna Raval, PhD, SVP of Translational Research, will attend the upcoming #ASH24 meeting. If you are interested in learning more about our company and our GenoPredicta and Immunopredicta platforms for multiple myeloma and other hematological malignancies, please reach out to schedule a meeting. We are looking forward to connecting with you! To learn more about our precision medicine solutions, visit our website at https://lnkd.in/ejKDK3Ss. #ASH2024 #TranslationalResearch #Hematology Email: info@predictabiosciences.com
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🚀 In-Depth from EHA 2024! Explore the latest insights from the EHA 2024 with Prof Dr Nathalie Meuleman from the Institut Jules Bordet in Brussels. In our new video, Prof Meuleman summarises the outcomes of the BENEFIT trial, which evaluates the impact of extending bortezomib use in combination with isatuximab, lenalidomide and dexamethasone (IsaRd) for newly diagnosed transplant-ineligible multiple myeloma (NDMM TI) patients. For all EHA 2024 videos, find the link in the comments! 👇 #MediMix #EHA2024 #Hematology #MultipleMyeloma #Innovation #BENEFITtrial
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Understanding underlying molecular mechanisms of inherited retinal degenerations is crucial for developing therapies. Contribute your original research article for ARVO TVST journal's special issue on advances in cellular/molecular pathology of IRDs. Submit by Dec. 31. https://bit.ly/3YNw6T1 #ARVOjournals #OpenAccess #VisionResearch #ophthalmology
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#HighlyCitedPapers 📝 Pathology and Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease-Associated Hepatic Tumors — Takahashi, et al. In this paper, the authors aimed to outline the pathology and pathogenesis of MASLD-associated liver tumors. Full text is available 👇 https://lnkd.in/dJT5uJWe #medicine #health #research #science
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Piperlongumine is well-known for its function as a senolytic substance, along with well-documented bioactivities, such as anti-inflammatory, antioxidant, and anticancer effects and anti-diabetic, anti-obesity, and neuroprotective properties. In this paper the cell viability was measured with the Celloger Mini Plus. #cellculture #livecellimaging #cellviability
Congratulations to the collaborative teams led by Prof. Do-Yeon Kim and Prof. Wanil Kim on their recent research investigating the effects of the piperlongumine’s senolytic activity on the skin. The team discovered that piperlongumine increases the expression of genes essential for skin barrier function and ceramide synthesis, as well as to influence the secretion of cytokines and aging markers in epidermal keratinocytes. These findings suggest that piperlongumine may positively impact the physiological activity of epidermal keratinocytes and improve skin health by regulating significant skin-related genes. In this study, to assess the survival of human keratinocytes in response to piperlongumine treatment, a live cell imaging technique was used to track the dynamic changes in cell viability. HaCaT cells and primary human keratinocytes were incubated with piperlongumine at various concentration, and images were taken at 3-hour intervals for 42 hours using an automated live-cell imaging system, Celloger® Mini Plus. We appreciate Celloger® being part of the research. To read the full article: https://lnkd.in/gGUJ6bbX More information about Celloger® Mini Plus: https://lnkd.in/g8CTm7hW #livecellimaging #Celloger #CellogerMiniPlus #Curiosis #piperlongumine #keratinocyte #cellviability
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Join our Co-founder and CEO, Alvin Luk, and Sr. Director of Business Development, Xixi Zhu, at #BIO2024 organized by Biotechnology Innovation Organization from June 3-6 in San Diego, where we’ll showcase our #CNS (#ALS , #Alzheimer, #MECP2 Duplication Syndrome ), #neuromuscular (#DMD ), and ophthalmology (#RPE65 #inheritedblindness , #LCA, #maculardegeneration ) pipeline and our proprietary #CRISPR -based HG-PRECISE platform discovering #novel CRISPR #nucleases. We’re excited to connect with you and discuss how we can shape the future of genomic medicine together. Don’t forget to #schedule a one-on-one partnering session with Xixi Zhu in advance to discuss potential #partnerships or #collaborations. #genetherapy #geneediting #genomeediting #Alzhiemer #AlzheimersResearch #Dementia #MECP2Dup #AmyotrophicLateralSclerosis #neuroscience #partnering #collaboration #opportunities #businessdevelopment #biotechnology #pharmacueticals #crossboarder #medicine #innovation
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Medical Laboratory Scientist (Specialized in Cytopathology and Histopathology) Internal Quality Auditor and consultant ISO 15189:2012,2022, ISO 19011:2012 Laboratory Management
DML Histopathogy- Macoscopic image of nephroblastoma (Wilms’s tumour) showing chemotherapy induced changes occupying 50% of the mass(necrotic tissue). Tumour is focally surrounded by a fibrous (pseudo)capsule which is infiltrated by viable tumour, which does not reach the outer surface or perenal fat. Viable tumour infiltrates the soft tissue of the renal sinus, but free of resection margin. Sample grossed, processed and reported in 3 working days. #Pathologyyoucantrust #DML #Histology #Renalbiopsy #Kidney #Labwork #pathology #servingcommunity # pathology
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Organoids are 3D in vitro culture systems derived from self-organizing #stemcells. They can recapitulate the in vivo architecture, functionality, and genetic signature of original tissues. Thus, organoid technology has been rapidly applied to understanding #stemcellbiology, organogenesis, and various human pathologies. The recent development of human patient-derived organoids has enabled disease modeling with precision, highlighting their great potential in #biomedical applications, translational medicine, and #personalizedtherapy. Read More: https://lnkd.in/g5ZiZGdG
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🌟 Attending #ECP2024? Don't miss the Computational Pathology Symposium this morning in Spadolini 2! At 9:00, Leslie Tessier, PhD Candidate from the Computational Pathology Group at Radboudumc, is presenting the findings from a clinical performance study of Aiosyn Mitosis Breast. This study, conducted with 28 pathologists from 9 countries, highlights significant improvements in efficiency and consistency when using Aiosyn Mitosis Breast for mitosis counting. Stop by booth #89 for a live demo of Aiosyn Mitosis Breast and explore our advanced precision pathology solutions. #digitalpathology #computationalpathology #innovationinhealthcare
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🩸 Shaping the Future of Multiple Myeloma Care Through Real-World Evidence 🩸 Clinical trials capture only a portion of patients with multiple myeloma, with older, comorbid patients particularly underrepresented. With the approval of many new, effective substances, numerous questions remain about treatment sequences. These issues can only be addressed through high-quality, prospective real-world evidence. I am therefore very excited about the #ASH2024 poster session on the following abstract: „Second interim analysis from IONA-MM, an ongoing, non-interventional, multinational, observational study of RRMM“ (#2411e). #WeAreBiotech #Iwork4Amgen #ASH2024 #Hematology
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Bringing novel therapies to cancer patients as a Project Team Leader for Oncology at Genentech
3wSorry that I'm not going to ASH this year! Catch you another time