Rakesh Jain, MD, MPH’s Post

View profile for Rakesh Jain, MD, MPH, graphic

Physician - Psychiatry

Wow!! Congrats David and Sanjay. You two are the brightest stars in the galaxy of psychiatric thought leaders. Well done! Ketamine and esketamine (Spravato) are both hugely innovative and often life saving medications. A full chapter such as this in the major text book on psychopharmacology is a very positive development.

View profile for David Mathai, MD, graphic

Medical Director, Psychiatry & Psychedelic Research, Sattva Medicine

Our new chapter on #ketamine and #esketamine is out! It's hard to believe that 7 years have passed since Sanjay and I published the previous version in the APA Textbook of Psychopharmacology, 5th edition. So much has changed in that time and, while we've done our best to capture how this clinical literature has evolved, there are also certainly areas we will have missed. This is ultimately a testament to the amount of inquiry and innovation happening in the ketamine, #dissociative therapy, and related #psychedelic therapy space. Here we review information on the history and discovery of ketamine, preclinical and clinical pharmacology, pharmacokinetic parameters, mechanism of action, indications and efficacy, side effects and toxicology, and drug-drug interactions. Other chapters follow the same format, each examining the drug classes that form the basis of modern psychopharmacological treatment. This textbook is a resource for clinicians at all levels of expertise. For those interested, copies of the 6th edition can be purchased at the following link: https://lnkd.in/es55w6uz

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Will Ratliff

RN, Paramedic, Co-Founder, Part-Owner, Director of Operations -> Transcend Health Solutions

7mo

I am always pumped to see anything written up about Ketamine, but I do think we should stop lumping Racemic Ketamine and Esketamine together. They are not the same.

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David Mathai, MD

Medical Director, Psychiatry & Psychedelic Research, Sattva Medicine

8mo

Thank you Rakesh!

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