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World Iron Deficiency Day, raises awareness about iron deficiency and its impact on health. Iron is crucial for oxygen transport and its deficiency can lead to anemia, fatigue and impaired immunity. Biochemical tests play a key role in diagnosing iron deficiency, including serum ferritin, transferrin saturation and total iron-binding capacity (TIBC), which assess iron storage and availability. Additionally, iron deficiency may exacerbate heart conditions by reducing oxygen delivery to cardiac tissues, potentially leading to heart failure or ischemia. (https://lnkd.in/ehwjuy87) #IronDeficiency #anemia #hemoglobin #health #diagnosis #healthy #immunity #deficiency #medical #student #biomedical #bioengineer #engineer #engineering #india #rms #analytica #dmlt #technician #medicare #certifications #Standard #Devices #heart #ecg #oxygen #job #career #hiring #opportunity #delhi #chennai #kolkata

The timing of Creatine Kinase-MB (CK-MB) and myoglobin testing is essential for accurately diagnosing and monitoring acute myocardial infarction (AMI) or heart attack. CK-MB levels begin to rise 3 - 6 hours after myocardial injury, peak within 12 - 24 hours and return to normal baseline after 2 - 3 days. In contrast, myoglobin is the earliest marker, rising within 1 - 4 hours, peaking at 6 - 9 hours and normalizing within 24 hours. Sequential testing of these biomarkers, especially in the first 24 hours, is critical for early detection and assessing the progression of cardiac damage. While myoglobin helps identify early injury, CK-MB provides greater specificity for cardiac muscle damage. Combining these tests with troponin ensures a comprehensive evaluation of myocardial injury. #trivia #facts #tips #biomedical #cardiac #heart #heartattack #healthy #health #test #student #medical #medicare #rms #analytica #biochemistry #dmlt #technician #technical #engineer #engineering #quality #india #manufacturer #oem #odm #pune #mumbai #delhi #chennai #bangalore #safe #care #patient #career #job #hiring #lab #hospital #doctor

Looking for thoughts on which direction your laboratory medicine/pathology qualifications and career may take? Here's a list: ✅Clinical laboratories ✅Clinical trials ✅ Research laboratories ✅ Entrepreneurship ✅ Academia ✅ Biotechnology companies ✅ Sales and marketing There's plenty of options and opportunities. Find the right information and network. Let's connect and hear more . . . #drbonolomashishi #virologist #savethenation #knowledgeispower #pathologist

OPTICAL BIOSENSORS[TECHNOLOGY] Optical biosensors are analytical tools that use a biorecognition element and optical sensing technology. They are known for being highly sensitive, reliable, and robust Optical biosensors offer great advantages over conventional analytical techniques because they enable the direct, real-time and label-free detection of many biological and chemical substances.  Optical biosensors have many applications, including: ·        Biomedical research Optical biosensors are used to detect and distinguish biomarkers in samples, such as viruses, bacteria, proteins, cells, and cancer. They can also provide real-time information on binding affinity and kinetics, which is useful for drug discovery.  ·        Environmental monitoring Optical biosensors can detect pesticides, pharmaceuticals, microorganisms, toxins, and heavy metals in water samples. ·        Food safety Optical biosensors can detect pathogens, pesticide and drug residues, heavy metals, and other toxic substances in food. ·        Home-testing Some optical biosensors are commercialized as test strips for home-testing, such as home pregnancy tests. #upsc #notes #pune #notes #india #mains #success #bygrayps #topper #motivation #result #student #rajyaseva #telengana #delhi

#neurologicaldisorders #taurine #therapy #neuroprotection Emergence of taurine as a therapeutic agent for neurological disorders https://lnkd.in/gSkvFWSF Central University of Haryana, Mahendergarh Sharda University Lovely Professional University Uttaranchal University National University of Malaysia (UKM) Taurine is a sulfur-containing, semi-essential amino acid that occurs naturally in the body. It alternates between inflammation and oxidative stress-mediated injury in various disease models. As part of its limiting functions, taurine also modulates endoplasmic reticulum stress, Ca2+ homeostasis, and neuronal activity at the molecular level. Taurine effectively protects against a number of neurological disorders, including stroke, epilepsy, cerebral ischemia, memory dysfunction, and spinal cord injury. Although various therapies are available, effective management of these disorders remains a global challenge. Approximately 30 million people are affected worldwide. The design of taurine formation could lead to potential drugs/supplements for the health maintenance and treatment of central nervous system disorders. The general neuroprotective effects of taurine and the various possible underlying mechanisms are discussed in this review. This article is a good resource for understanding the general effects of taurine on various diseases. Given the strong evidence for the neuropharmacological efficacy of taurine in various experimental paradigms, it is concluded that this molecule should be considered and further investigated as a potential candidate for neurotherapeutics, with emphasis on mechanism and clinical studies to determine efficacy.

𝗣𝗲𝗿𝗶𝘁𝗼𝗻𝗲𝗮𝗹 𝗗𝗶𝗮𝗹𝘆𝘀𝗶𝘀 𝗠𝗮𝗿𝗸𝗲𝘁 𝟮𝟬𝟮𝟱-𝟮𝟬𝟯𝟭. 𝗚𝗹𝗼𝗯𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗥𝗲𝗽𝗼𝗿𝘁 𝗥𝗲𝗾𝘂𝗲𝘀𝘁 𝗳𝗼𝗿 𝗥𝗲𝗽𝗼𝗿𝘁 𝗦𝗮𝗺𝗽𝗹𝗲 𝗼𝗿 𝗥𝗲𝗽𝗼𝗿𝘁 𝗖𝘂𝘀𝘁𝗼𝗺𝗶𝘇𝗮𝘁𝗶𝗼𝗻: https://lnkd.in/dp3XzPcK This report provides a detailed and comprehensive analysis of the global Peritoneal Dialysis market, offering both quantitative and qualitative insights across various dimensions, including manufacturers, regions, countries, types, and applications. Given the dynamic nature of the market, the report examines competition, supply and demand trends, and key factors influencing market changes across multiple regions. It includes company profiles, product examples, and market share estimates for leading players in 2024. The market is segmented by type and application, with growth forecasts and consumption estimates for 2019-2031. These insights can assist businesses in identifying and targeting niche markets to expand their operations. 𝗔𝗱𝗱𝗶𝘁𝗶𝗼𝗻𝗮𝗹 𝗽𝗼𝗶𝗻𝘁𝘀: *Detailed regional and country-specific analysis of market trends. *Competitive landscape with key players’ strategies. *Projected market growth from 2019 to 2031. *Key drivers and challenges shaping the market's future. *In-depth examination of types and applications contributing to market expansion. *Insights into emerging market opportunities and risks. *𝗕𝘆 𝗧𝘆𝗽𝗲: Peritoneal Dialysis Machine, Peritoneal Dialysis Solution, Other *𝗕𝘆 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻: Hospital, Dialysis Center, Home *𝗕𝘆 𝗥𝗲𝗴𝗶𝗼𝗻: North America, Europe, Asia-Pacific, South America, Middle East & Africa *𝗕𝘆 𝗞𝗲𝘆 𝗣𝗹𝗮𝘆𝗲𝗿𝘀: Baxter International Inc., Fresenius Medical Care, Terumo Neuro, Huaren Pharmaceutial Co., Ltd, China Resources Double－Crane Pharmaceutical Co., Ltd., Chengdu Qingshan Industrial Co., Ltd., Shandong Weigao Group Medical Polymer Co.,Limited., NewSol, Fuzhou Dongze Medical Device Co., Ltd., Morestep Path Labs, VR Medical #PeritonealDialysis #DialysisTreatment #KidneyFailure #ChronicKidneyDisease #EndStageRenalDisease #DialysisSolutions #HomeDialysis #KidneyHealth #PDTechnology #PeritonealDialysisKit #DialysisMachine #DialysisTherapy #PDTraining #PeritonealDialysisSolutions #DialysisCare #KidneyCare #MedicalDevices #ChronicKidneyCare #KidneyTransplantAlternatives #DialysisMarket

#hematology ■ simple explanation on how the machine works and other important hints to be followed 👌 used to count and characterize blood cells, including red blood cells, white blood cells, and platelets. It can provide information about the cell counts, size and shape, this helps to diagnose various blood disorders and conditions. This can be achieved in the following steps; 1. sample preparation, the sample is diluted and mixed with reagents. 2. aspiration, the prepared sample is aspirated into the analyzer through a sample probe and capillary tube. 3. analysis, blood sample passes through various set of steps so as to analyse different aspects of blood. steps of analysis; •cell counting •cell sizing and differentiation •hemoglobin measurement •platelet analysis 4. data analysis, processes the data collected to obtain complete blood count. 5. result reporting, the result is displayed on the screen. #reagents •diluent which dilutes blood •lyse which breaks down red blood cells to release hemoglobin •detergent cleaner which is used to clean the system ■ Here are some important hints regarding hematology analyzer machines: 1. Calibration: Ensure regular calibration to maintain accuracy in cell counts and parameters. 2. Quality Control: Implement quality control measures to verify accuracy and precision. 3. Maintenance: Follow manufacturer guidelines for routine maintenance to keep the analyzer in a good condition. 4. Sample Preparation: Properly prepare blood samples according to the analyzer's requirements for accurate results. 5. Data Interpretation: Understand how to interpret the data generated by the analyzer as it will help you to make decisions. 6. Troubleshooting: make sure you know common issues and troubleshooting procedures to address any technical problems. 7. Safety: Adhere to safety protocols when handling samples and operating the analyzer to prevent accidents or contamination.

Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences A new method for analyzing urinary free cortisol (UFC) by liquid chromatography-tandem mass spectrometry (LC-MS/MS) is proposed. The method involves diluting the urine sample and mixing it with a methanol/water solution, then analyzing it directly using LC-MS/MS. The method is validated with good precision, recovery, and a wide linear range. It is recommended to not use preservatives for urine storage. The study confirms the potential of this LC-MS/MS assay for routine clinical testing.

Scientific Pricing of Medical Tests: A Detailed Example of Kidney Function Test Pricing Pricing medical tests requires a scientific methodology that balances the provision of high-quality services with financial sustainability. Let's explore this through the example of pricing a kidney function test, which typically measures serum creatinine and blood urea nitrogen (BUN), two key indicators of renal health. Key Factors in Pricing a Kidney Function Test: 1. Direct operational cost: Chemical reagents: The cost of reagents required to measure creatinine and urea levels. For this example, assume the cost of reagents per patient is $5. Equipment depreciation and maintenance: the analytical instruments used and the cost of their maintenance and depreciation. If the analyzer processes 1,000 tests monthly and the maintenance cost is $500 per month, the cost per test for equipment usage is $0.50. -Utilities and resources: Costs associated with electricity and water consumption in the laboratory, estimated at $0.20 per test. 2. Human Resources: Labor costs: the wages of the technicians and specialists performing the test. Assume the cost of labor for each test is $2. 3. General and administrative overheads: rent and insurance: If monthly rent and insurance costs are $2,000 and the laboratory conducts 4,000 tests per month, the share of these costs allocated to the kidney function test would be $0.50 per test. 4. Demand and Volume: Larger test volumes enable cost reduction per test, as fixed costs are spread across more procedures. Higher demand for the test can lower the overall test cost due to economies of scale. A Detailed Example of Kidney Function Test Pricing: Assume the laboratory conducts 1,000 kidney function tests monthly, with costs as follows: Reagents: $5.00 Equipment depreciation and maintenance: $0.50 Utilities: $0.20 Labor costs: $2.00 General overheads: $0.50 The total cost per test is $8.20. Now, adding a profit margin based on market standards and operational requirements, let’s assume a profit margin of 30%. The final price to the patient would be: $8.20 × 1.30 = $10.66. The Importance of Scientific Pricing Scientific pricing helps to ensure the sustainability of the laboratory and its capacity to consistently deliver high-quality services. Offer fair pricing that aligns with the quality provided and market competition. Promote transparency, which is crucial for laboratories aiming to build long-term trust with patients. #ScientificPricing #MedicalTests #KidneyFunctionTest #QualityAndCost #LaboratoryManagement #Healthcare

1/2. Title:“Management of Troponin Levels: A Biochemical Approach Using Organic and Inorganic Physical Chemistry and Probiotics” Inorganic Physical Chemistry: The Role of Pharmaceuticals in Troponin Management: Pharmaceutical interventions play a vital role in managing elevated troponin levels, particularly through the use of medications that regulate blood pressure, cholesterol, and inflammation. Medications such as beta-blockers, ACE inhibitors, and statins reduce the cardiac workload and prevent further damage, effectively lowering troponin levels. Mechanisms: • Beta-blockers and Calcium Channel Blockers: These medications reduce the heart’s workload by controlling heart rate and blood pressure, indirectly reducing troponin release during episodes of cardiac stress. • Statins: Statins lower cholesterol levels and reduce inflammation in the blood vessels, both of which can reduce cardiac stress and troponin levels. • Anti-inflammatory Drugs: By reducing systemic inflammation, these medications help prevent further cardiac injury, reducing the need for the release of troponin as a stress marker. Magnetic Resonance Forces and Conductivity in Managing Troponin Levels: The conductivity of natural elements within the body, particularly through the influence of magnetic resonance fields, plays an important role in cellular function and cardiac health. In the context of troponin management, magnetic resonance forces influence how energy and signals are transmitted within cells, particularly those in the heart muscle. These fields affect ion channels and the movement of key elements like calcium, which are essential for maintaining proper cardiac rhythm and muscle contraction. Mechanisms: • Magnetic Conductivity of Natural Elements: Elements like iron and magnesium are essential for maintaining magnetic field resonance within the heart. These elements interact with the body’s magnetic fields to regulate ion exchange, thereby ensuring stable heart function and reducing the risk of elevated troponin release. • Electromagnetic Influence on Cardiac Cells: The body’s intrinsic electromagnetic fields help to regulate the electrical activity of cardiac cells. Disruptions in these fields, such as those caused by electrolyte imbalances or oxidative stress, can increase troponin levels due to stress on the heart. Courtesy to Dr.Holly Butt Cardiologist,Auckland City Hospital,NewZealand Courtesy to Priya Waller Media and Communications Experts UK 🇬🇧