Sacha Lynch’s Post

It's an ambitious target: Recommendation 4 "By 2027, high-income countries should commit to only prescribing #antibiotics (with a few defined exceptions) when need is confirmed by a diagnostic test. Low- and middle-income countries should achieve this by 2030." Perhaps what we need is a graphic that illustrates diagnostic product-market fit alongside cost and context i.e. primary care vs secondary? How many diagnostics will integrate with the current clinical workflows and what level of data linkage and interoperability is needed to be able to monitor and evaluate success? Ara Darzi Alison Holmes Pathology Technology Australia

The first World Innovation Summit for Health (WISH) report on antimicrobial resistance (AMR) in over a decade reflects on global progress in tackling AMR since, considers opportunities for action, and makes policy recommendations to build on the United Nations Political Declaration of the High-Level Meeting on Antimicrobial Resistance. The Fleming Initiative will have a strong presence at the World Innovation Summit for Health (WISH) next week, where 'Tackling Antimicrobial Resistance: How to Keep Antibiotics Working for the Next Century' will be presented. As the report's sixth recommendation highlights, we have four years before the centenary of the discovery of penicillin (2028) to accelerate progress on tackling AMR. Let's keep antibiotics working for the next 100 years! The report was co-authored by: 🔵 Lord Ara Darzi, Executive Chair of the Fleming Initiative 🔵 Dame Sally Davies, UK Special Envoy on Antimicrobial Resistance 🔵 Peter Howitt, Managing Director of the Centre for Health Policy (Institute of Global Health Innovation) 🔵 Anant Pratap Singh, Medical Biosciences Student (Imperial College London) Read the report ⤵️ https://lnkd.in/eSaSaDwp

The first World Innovation Summit for Health (WISH) report on antimicrobial resistance (AMR) in over a decade reflects on global progress in tackling AMR since, considers opportunities for action, and makes policy recommendations to build on the United Nations Political Declaration of the High-Level Meeting on Antimicrobial Resistance. The Fleming Initiative will have a strong presence at the World Innovation Summit for Health (WISH) next week, where 'Tackling Antimicrobial Resistance: How to Keep Antibiotics Working for the Next Century' will be presented. As the report's sixth recommendation highlights, we have four years before the centenary of the discovery of penicillin (2028) to accelerate progress on tackling AMR. Let's keep antibiotics working for the next 100 years! The report was co-authored by: 🔵 Lord Ara Darzi, Executive Chair of the Fleming Initiative 🔵 Dame Sally Davies, UK Special Envoy on Antimicrobial Resistance 🔵 Peter Howitt, Managing Director of the Centre for Health Policy (Institute of Global Health Innovation) 🔵 Anant Pratap Singh, Medical Biosciences Student (Imperial College London) Read the report ⤵️ https://lnkd.in/eSaSaDwp

A really insightful (and terrifying) report on the state of AMR tracking. To me, two things really stood out: 1. The need for more public awareness (of course, mostly among those working in health care, but I do think general awareness is important) 2. The need to fund more research on finding more antimicrobials (and this is where the public awareness and pressure on the politicians would come in!) See what I did there? Even if you don't read the full paper, you already know a bit more from just reading this post. But seriously, read it, this is important.

🌍💊 Tackling the #Silent #Pandemic: Antimicrobial Resistance (#AMR) We were very interested to follow the crucial debate on #AMR at the #PoliticoHealthcare Summit 2024. The session comes in the middle of the #World #AMR #Awareness #Week and underscored the urgent need for global action to address AMR, a crisis predicted to cause 40 million deaths in the coming years. 🗝 Key takeaways: 1️⃣ AMR Targets Are Not Being Met: While progress is evident, regions like Europe must accelerate national action plans and boost innovation in diagnostics and treatments. 2️⃣ Patient-Centric Policies: Patient organizations are vital in shaping effective policies and raising awareness. 3️⃣ Global Investment Required: From new drugs and clean water to prevention and healthcare workforce stewardship, sustained funding is essential to reduce the future costs of AMR. 4️⃣ Innovative Financial Models: Countries exploring subscription models and public-private partnerships are paving the way for a sustainable approach to combating AMR. 5️⃣ Pan-European Coordination: A united EU response, with a focus on 2025 as a year of action—not transition—is critical to keeping AMR on the political agenda. The urgency of the AMR crisis cannot be overstated, and we applaud the collaborative efforts highlighted during this summit. Let’s ensure that 2025 and beyond see tangible progress in addressing this global health threat. #AMR #HealthAwareness #Antibiotics #GlobalHealth #Prevention #AMR #PatientVoices #HealthcareInnovation #EAAD #AntimicrobialResistance #KeepAntibioticsWorking #AMRPatientGroup #PatientsFirst #EUHealthcare #WAAW2024 European Centre for Disease Prevention and Control (ECDC) DG SANTE European Commission European Patients' Forum Anca Toma Health First Europe European Medicines Agency World Health Organization (WHO) Active Citizenship Network AMR Patient Alliance Antibiotic Research UK AVEC France European Forum for Primary Care (EFPC) European Lung Foundation Fondazione The Bridge International Alliance of Patients' Organizations (IAPO) NGO Karkinaki Awareness for Childhood and Adolescent Cancer Health Consultancy Network (Malta) Patients for Patient Safety Foundation PELVIC PAIN SUPPORT NETWORK Associazione Respiriamo Insieme The AMR Narrative The Patients Association UNIAMO Federazione Italiana Malattie Rare CZEPAR - Česká platforma antibiotické rezistence

The invisible threat: How climate change, health factors and access to medical products are driving antimicrobial resistance (AMR). In a world where pandemics pose an ever-increasing threat, it is critical to understand and combat the full extent of AMR.   Last week, the Swiss Agency for Development and Cooperation participated at the AMR Conference in Basel, where strategies and the specific challenges the innovation ecosystem faces in bringing new antimicrobial treatments and diagnostics to the market were discussed.   The SDC was advocating for:   🔸 Ensuring access to essential antibiotics for people in low- and middle-income countries. 🔸 Promote sustainable, affordable and effective antibiotics. 🔸 Improve the systems and partnerships needed to distribute these antibiotics to those in need. 🔸 Continued commitment from policy makers, joint country efforts and cross-sectoral collaboration.   The aim is to ensure the effectiveness of these vital medicines for the wellbeing of future generations.  #powerofantibiotics Global Antibiotic R&D Partnership (GARDP) World Health Organization MedAccess BEAM Alliance

🎞️ Watch our webinar recording Last month, we held a webinar on "Promising Research Horizons: The TCIH’s Contribution to Tackling AMR in Europe", where we examined the role of Traditional and Complementary Integrative Healthcare (TCIH) in addressing antimicrobial resistance (AMR) within the One Health framework. Key takeaways: ▫️ TCIH as a solution to AMR: Highlights included TCIH's potential to reduce antibiotic overuse and promote preventive, holistic approaches to infection management. ▫️ One Health approach: Speakers emphasised TCIH's role in fostering cross-sectoral collaboration between human, animal, and environmental health, contributing to sustainable AMR solutions. ▫️ Global cooperation: Insights from international research projects underscored the need for worldwide collaboration in advancing TCIH research and application. ▫️ Future research priorities: Calls for increased investment and stronger policies to integrate TCIH into AMR strategies. From innovative field trials to microbiome-focused strategies, the discussions showed how TCIH can lead to impactful, evidence-based interventions. Watch the recording here: https://lnkd.in/e6xM22Xn This webinar is organised by EUROCAM in cooperation with Charité Competence Center for Traditional and Integrative Medicine (CCCTIM), Charité - Universitätsmedizin Berlin. #AMR #AntimicrobialResistance #TCHI #TraditionalComplementaryIntegrativeHealthcare #Webinar #OneHealth #Sustainable #EuropeHealth #RefocusingHealth

🌟World AMR Awareness Week | Resources🌟 The International Society of Antimicrobial Chemotherapy (ISAC) and the The Alliance for the Prudent Use of Antibiotics (APUA) Alliance for the Prudent Use of Antibiotics (APUA) are proud supporters of World AMR Awareness Week 2024 (WAAW). We have compiled a useful list of resources / events from organisations committed to combatting AMR which are happening across the world to mark WAAW including webinars, symposia and toolkits. https://lnkd.in/ekmPaNDS If your event is not on the list, email secretariat@isac.world for it to be added. There has never been a better time to raise awareness of this global public health issue. #worldamrawarenessweek #WAAW #WAAW2024 #Worldantimicrobialawarenessweek #bacteria #antimicrobialresistance #clinicalmicrobiology #antibioticresistance #publichealth #antibiotics #infectiousdiseases #antimicrobials #antimicrobial #healthcare #antimicrobialstewardship #onehealth #globalhealth

🌍✨ Closing World Antimicrobial Awareness Week: A Call to Action and Innovation ✨🌍 As we draw the curtain on World Antimicrobial Awareness Week, I am reminded that our fight against antimicrobial resistance (AMR) is not just a health challenge—it’s a global survival mission. 🚨 AMR claims the lives of 1.27 million people annually, disrupts economies, and threatens decades of medical progress. Yet, within this challenge lies an incredible opportunity for creativity, collaboration, and innovation. 🔬 Phage Therapy: Harnessing the power of bacteriophages to combat drug-resistant infections. 🌱 Sustainable Practices: Reducing misuse of antimicrobials in agriculture and healthcare. 🤝 Global Collaboration: Bridging gaps between researchers, policymakers, and communities to champion one health. As a researcher (and a bacteriophage enthusiast), I firmly believe that science, supported by innovation, can pave the way for a future free of superbugs. But we need everyone on board: Researchers: Push the boundaries of discovery. Healthcare professionals: Champion stewardship in every practice. Policymakers: Build frameworks that prioritize prevention. You: Spread awareness and demand action. This week may end, but our resolve must not. Let’s continue to innovate, advocate, and educate to secure a healthier future for generations to come. What role will YOU play in tackling AMR? Share your thoughts or initiatives below—let’s inspire each other to act! 💡💪 #WorldAntimicrobialAwarenessWeek #AMR #InnovationForHealth #PhageTherapy #GlobalHealth Amos Lucky Mhone Atif Khan African Youth Antimicrobial Resistance Alliance Task Force (AYARA-TF) Azam Haghighatfard Kuete Chanelle Phages IPR Phage Kenya Consortium Clare Chukwudebelu, PharmD, MPH Centre for Phage Research Leicester Phage Publishers Jesca Nakavuma Samuel Jefwa

The Joint Action JARDIN, launched on March 8, 2024, aims to integrate European Reference Networks (ERNs) into national health systems. The expected results from JARDIN, including recommendations, blueprints and reports from concrete pilot implementations are to stimulate the elaboration of improved national plans for rare diseases in EU Member States. The European Reference Networks (ERNs) are virtual networks involving healthcare providers across Europe. They aim to facilitate discussion on complex or rare diseases and conditions that require highly specialised treatment, and concentrated knowledge and resources. 24 ERNs are working on a range of thematic issues, including ERN-LUNG - European Reference Network for rare respiratory diseases, the European Reference Center for Rare Lung Diseases, which includes a core network on #pulmonaryhypertension. Five pulmonary hypertension patients/patient advocates sit on the ERN-LUNG Patient Advocacy Group, see list at this link: https://lnkd.in/dieSgfa9 Hall Skaara PHA Europe Natalia Maeva PHA Europe Gergely Meszaros JD, MSc Tüdőér Egylet Luc MATTHYSEN HTAP Belgique Pisana Ferrari Alliance for Pulmonary Hypertension https://lnkd.in/ddKJFJiT