SK pharmteco’s Post

Understanding the Critical Utility of Diluents in your Immunoassay:   Due to the variability within patient samples, different blocking strategies are needed to dilute samples to achieve maximum assay performance. For immunodiagnostic assays, a false positive or false negative result can lead to a misdiagnosis of a disease or condition and improper treatment decisions. Clinicians and patients depend on the in vitro diagnostics (IVD) industry to develop high quality assays that deliver accurate results consistently.   Surmodics IVD’s MatrixGuard™ Diluent and Assay Diluent (Protein-Free) are the gold standard for reducing false positives in your assay. These formulations provide two options to use when different methods are needed to block matrix interferences, while maintaining the clinical utility of the assay.   Visit the link below to learn more about the importance diluents have in building accurate and reliable immunoassays below and contact us below to request free samples of our diluents today.   https://lnkd.in/dkwhXS5h   https://lnkd.in/gwH7Ptk   SURMODICS, MATRXGUARD and the SURMODICS logo are trademarks of Surmodics, Inc. and/or its affiliates.   #diluents #immunoassay #elisa #diganostics #ivd #biotechnology

A successful contamination control strategy (CCS) is essential for cGMP compliance in CGT manufacturing. Our poster explores how G-Rex Bioreactors and Heracell Vios Incubators can empower you to establish a robust CCS and achieve superior production outcomes. Download it today: https://lnkd.in/eNhqhjix #celltherapy #genetherapy #CGT

🚀 Unlocking the Potential of PSC-derived therapies with Thermostable FGF-2 TOP® in cGMP Grade 🧫 💡 Why FGF-2 TOP® (Thermostability Optimized)? This groundbreaking recombinant protein is redefining #pluripotentstemcell culture by combining exceptional performance with cost efficiency. Developed by Core Biogenesis in collaboration with Nucleus Biologics to meet GMP-compliant quality attributes, this product brings several Key Benefits: ✔️ Supports Pluripotency: Maintains high-quality iPSC cultures with robust expression of pluripotency markers, even under various media feeding regimes and concentrations. ✔️ Enables Cost Reduction: Achieve equivalent results with every-other-day (EOD) feeding compared to daily supplementation with traditional FGF-2, reducing media costs without compromising quality. ✔️ Scales with Ease: Its thermostable nature ensures stability and consistency, making it ideal for large-scale manufacturing processes. ✔️ GMP Integration: Start integrating GMP-grade materials early in discovery and manufacturing to streamline the pathway toward cell therapies. 🫴 Explore the benefits of FGF-2 TOP® in your cell manufacturing process requesting your product offer here: https://lnkd.in/eXTG3S8h #celltherapy #pluripotentstemcells #rawmaterials #costreduction #patientaccess

The StabilCoat® Immunoassay Stabilizer from Surmodics IVD, Inc. now features a Bioz Badge on its product page! This provides instant access to valuable scientific literature and citation metrics, enhancing product validation and credibility directly on the page. Check it out! #Bioz #CitationData #ScientificResearch #ProductValidation #Surmodics

Canton Biologics' DTEasy (Difficult to Express) platform is distinguished by its efficacy and versatility. We provide a comprehensive range of vectors meticulously engineered to address varying levels of expression difficulty. 📌 In one instance, regarding tissue plasminogen activator (t-PA): Challenges we faced: 1) the non-covalent complex formed between t-PA and its inhibitor exhibited a loosely structured nature, facilitating separation; 2) the traditional purification process for t-PA generally requires three to four steps to achieve purity exceeding 90%. Solutions: We developed a dual expression vector that co-expresses t-PA in conjunction with its inhibitor, complemented by an efficient one-step chromatographic purification process. Results: The final purified yield of t-PA reached an impressive 361.5 mg/L, surpassing current technological benchmarks by more than threefold. 📈 📩 Contact us: BD@cantonbio.com #BiotechInnovation #DTEasyPlatform #ProteinExpression 

Exciting advancements in bioprocessing! Discover how Repligen's #ProStream and #HyStream tangential flow filtration cassettes are enhancing efficiency and reliability in antibody-drug conjugate (ADC) production. These cutting-edge technologies offer superior performance, ensuring high-quality outcomes in complex ADC processes. Let's embrace innovation in biomanufacturing! #Bioprocessing #Innovation #ADC #Repligen

🧬 Just in! Discover how Biozen™ dSEC-7 analyzes and controls EGFP IVT mRNA aggregates, optimizing mRNA vaccine and drug production. Achieve high resolution and sensitivity with SEC, ensuring product quality and efficacy. 🌟 Download it here: https://bit.ly/4dEQJpY Want to dive into the full discussion and explanation? Check out our webinar: https://bit.ly/3U5emkx #mRNA #Chromatography #Biotech #VaccineDevelopment

𝙔𝙤𝙪 𝙣𝙚𝙚𝙙 𝙞𝙣𝙛𝙤𝙧𝙢𝙖𝙩𝙞𝙤𝙣 𝙩𝙤 𝙢𝙖𝙠𝙚 𝙙𝙚𝙘𝙞𝙨𝙞𝙤𝙣𝙨. PTMs, such as deamidation, glycation and sialylation, can affect a protein's charge. It is important to understand a protein’s charge profile and how to control it before upstream process development. Learn how Johnson & Johnson was able to use icIEF-UV/MS to get the information they needed faster than ever before. Listen to their story here 👇 #mAb #icIEF #ProcessDevelopment #Biopharma

This paper reviews recent advancements in using nanoliposomes (NLPs) for treating fungal infections, highlighting their effectiveness, advantages over conventional therapies, and safety concerns. It covers encapsulated antifungal agents and strategies for site-specific targeting in oral, parenteral, and transdermal applications. You can check it out here: https://lnkd.in/g39-vVQh #Nanotechnology #DrugDelivery #Biomedical #Pharmaceuticals #Biotechnology #Innovation #Healthcare #Research #Biocompatibility #MedicalScience